Letter: The Paramedian Supracerebellar-Transtentorial Selective Amygdalohippocampectomy for Mediobasal Temporal Epilepsy

2018 ◽  
Vol 15 (3) ◽  
pp. E33-E33 ◽  
Author(s):  
Atilla Erdem
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Bastian David ◽  
Jasmine Eberle ◽  
Daniel Delev ◽  
Jennifer Gaubatz ◽  
Conrad C. Prillwitz ◽  
...  

AbstractSelective amygdalohippocampectomy is an effective treatment for patients with therapy-refractory temporal lobe epilepsy but may cause visual field defect (VFD). Here, we aimed to describe tissue-specific pre- and postoperative imaging correlates of the VFD severity using whole-brain analyses from voxel- to network-level. Twenty-eight patients with temporal lobe epilepsy underwent pre- and postoperative MRI (T1-MPRAGE and Diffusion Tensor Imaging) as well as kinetic perimetry according to Goldmann standard. We probed for whole-brain gray matter (GM) and white matter (WM) correlates of VFD using voxel-based morphometry and tract-based spatial statistics, respectively. We furthermore reconstructed individual structural connectomes and conducted local and global network analyses. Two clusters in the bihemispheric middle temporal gyri indicated a postsurgical GM volume decrease with increasing VFD severity (FWE-corrected p < 0.05). A single WM cluster showed a fractional anisotropy decrease with increasing severity of VFD in the ipsilesional optic radiation (FWE-corrected p < 0.05). Furthermore, patients with (vs. without) VFD showed a higher number of postoperative local connectivity changes. Neither in the GM, WM, nor in network metrics we found preoperative correlates of VFD severity. Still, in an explorative analysis, an artificial neural network meta-classifier could predict the occurrence of VFD based on presurgical connectomes above chance level.


Epilepsia ◽  
2016 ◽  
Vol 57 (11) ◽  
pp. 1789-1797 ◽  
Author(s):  
Thomas Sauvigny ◽  
Katja Brückner ◽  
Lasse Dührsen ◽  
Oliver Heese ◽  
Manfred Westphal ◽  
...  

2016 ◽  
Vol 30 (4) ◽  
pp. 272-278 ◽  
Author(s):  
Antoine Verger ◽  
Yalcin Yagdigul ◽  
Axel Van Der Gucht ◽  
Sylvain Poussier ◽  
Eric Guedj ◽  
...  

2017 ◽  
Vol 100 ◽  
pp. 665-674 ◽  
Author(s):  
Enrico Ghizoni ◽  
Roger Neves Matias ◽  
Stefan Lieber ◽  
Brunno Machado de Campos ◽  
Clarissa Lin Yasuda ◽  
...  

2007 ◽  
Vol 73 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Shigeo Ito ◽  
Tetsuya Suhara ◽  
Hiroshi Ito ◽  
Fumihiko Yasuno ◽  
Tetsuya Ichimiya ◽  
...  

2015 ◽  
Vol 86 (11) ◽  
pp. e4.155-e4
Author(s):  
Ray Wynford-Thomas ◽  
Rob Powell

Just as ‘no man is an island’, despite its misleading name, the insula is not an island. Sitting deeply within the cerebrum, the insular cortex and its connections play an important role in both normal brain function and seizure generation. Stimulating specific areas of the insula can produce somatosensory, viscerosensory, somatomotor and visceroautonomic symptoms, as well as effects on speech processing and pain. Insular onset seizures are rare, but may mimic both temporal and extra-temporal epilepsy and if not recognised, may lead to failure of epilepsy surgery. We therefore highlight the semiology of insular epilepsy by discussing three cases with different auras. Insular onset seizures can broadly be divided into three main types both anatomically and according to seizure semiology:1. Seizures originating in the antero-inferior insula present with laryngeal constriction, along with visceral and gustatory auras (similar to those originating in medial temporal structures).2. Antero-superior onset seizures can have a silent onset, but tend to propagate rapidly to motor areas causing focal motor or hypermotor seizures.3. Seizures originating in the posterior insula present with contralateral sensory symptoms.


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