scholarly journals Prevalence of Anti-HCV Antibody Among the General Population in Mainland China Between 1991 and 2015: A Systematic Review and Meta-analysis

2019 ◽  
Vol 6 (3) ◽  
Author(s):  
Yuhua Gao ◽  
Jun Yang ◽  
Feng Sun ◽  
Siyan Zhan ◽  
Zhongliao Fang ◽  
...  
Keyword(s):  
Systematic Review ◽  
General Population ◽  
Selection Criteria ◽  
Population Studies ◽  
Meta Analysis ◽  
Mainland China ◽  
Lower Prevalence ◽  
Prevalence Rates ◽  
General Population Studies ◽  
Hcv Antibody

Abstract Our study aims to estimate the burden of hepatitis C virus (HCV) infection among the general population in Mainland China. We searched 4 databases for studies of the prevalence of anti-HCV antibody among the general population. Studies that met the selection criteria were included in the meta-analysis. Ninety-four studies with 10729 929 individuals were finally included. Overall, the prevalence of anti-HCV antibody among the general population in Mainland China is 0.91% (95% confidence interval, 0.81%–1.03%). The prevalence rates of anti-HCV antibody were geographically different, with a range of 0.32%–6.51%, and the East and South of China had a relatively lower prevalence. The prevalence of anti-HCV antibody increased successively from 0.16% to 3.95% with advancing age. It was noteworthy that the prevalence of anti-HCV antibody decreased continuously from 2.09% to 0.45% during 1991–2010, whereas it increased to 0.58% during 2011–2015.

scholarly journals Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Gita Shafiee ◽  
Abbasali Keshtkar ◽  
Akbar Soltani ◽  
Zeinab Ahadi ◽  
Bagher Larijani ◽  
...  
Keyword(s):  
Systematic Review ◽  
General Population ◽  
Population Studies ◽  
Meta Analysis ◽  
General Population Studies ◽  
The World

scholarly journals The Prevalence of Olfactory Dysfunction in the General Population: A Systematic Review and Meta-analysis

2020 ◽  
pp. 194589242094625 ◽  
Author(s):  
Vincent M. Desiato ◽  
Dylan A. Levy ◽  
Young Jae Byun ◽  
Shaun A. Nguyen ◽  
Zachary M. Soler ◽  
...  
Keyword(s):  
Systematic Review ◽  
General Population ◽  
Meta Analysis ◽  
Olfactory Dysfunction ◽  
Prevalence Rates ◽  
Early Indicator ◽  
Testing Method ◽  
Objective Tests ◽  
Assessment Metrics ◽  
Older Subjects

Background Olfactory dysfunction (OD) is common and has been reported as an early indicator of COVID-19. However, the reported prevalence of OD in the general population varies widely depending upon the metric used to assess olfaction. Methodology/Principal: To perform a systematic review and meta-analysis of the prevalence of OD in the healthy general population, review the various assessment metrics used, and compare pooled OD prevalence rates. Results A total of 175,073 subjects were identified (mean age 63.5 years, range 18 to 101) with an overall OD prevalence of 22.2% (95% CI 14.8–30.6). OD prevalence was significantly greater using objective olfactory assessments, compared to subjective measures (28.8%, CI 20.3–38.2 versus 9.5%, CI 6.1–13.5, p < 0.001). The prevalence of OD was greater using expanded identification tests (>8 items) compared to brief test with ≤8 items (30.3%, CI 16.2–46.5 versus 21.2%, CI 12.3–31.8). Prevalence was higher in studies with a mean age greater than 55 years compared to those with a mean age of 55 years or less (34.5%, CI 23.4–46.5 versus 7.5%, CI 2.6–14.5, p < 0.001). Conclusions The reported prevalence of OD in the general population depends on the testing method and population age. OD prevalence was greater in studies using objective tests, expanded identification tests, and in those with older subjects.

scholarly journals Declining HIV incidence in sub-Saharan Africa: a systematic review and meta-analysis of empiric data

2020 ◽  
Author(s):  
Keya Joshi ◽  
Justin Lessler ◽  
Oluwasolape Olawore ◽  
Gideon Loevinsohn ◽  
Sophrena Bushey ◽  
...  
Keyword(s):  
Systematic Review ◽  
Population Studies ◽  
Meta Analysis ◽  
Central Africa ◽  
Sub Saharan Africa ◽  
Hiv Incidence ◽  
General Population Studies ◽  
Incidence Data ◽  
Sub Saharan ◽  
Over Time

ABSTRACTBackgroundUNAIDS models suggest HIV incidence is declining in sub-Saharan Africa; however, it is unclear whether modeled trends are supported by empirical evidence.MethodsWe conducted a systematic review and meta-analysis of adult HIV incidence data from sub-Saharan Africa by searching Embase, Scopus, PubMed, and OVID databases and technical reports published between January 1, 2010 and July 23, 2019. We included studies that directly measured incidence from blood samples. Incidence data were abstracted according to population risk group, geographic location, sex, intervention arm, and calendar period. Weighted regression models were used to assess incidence trends across general population studies by sex. We also identified studies reporting ≥3 incidence measurements since 2010 and assessed trends within them.Findings292 studies met inclusion criteria. Most studies were conducted in South Africa (n=102), Uganda (n=46), and Kenya (n=41); there were 27 countries with no published incidence data, most in western and central Africa. Across general population studies, average annual incidence declines since 2010 were 0.16/1000 person-years (95%CI:0.06-0.26;p=0.004) among men and 0.16/1000 person-years (95%CI: −0.01-0.33;p=0.060) among women in eastern Africa, and 0.25/1000 person-years (95%CI:0.17-034;p<0.0001) among men and 0.42/1000 person-years (95%CI:0.23-0.62;p=0.0002) among women in southern Africa. In 9/10 studies with multiple measurements, incidence declined over time. Incidence was typically higher in women than men (median ratio=1.45, IQR: 1.12-1.83) with increasing sex disparity over time.InterpretationEmpirical incidence data show the rate of new HIV infections is declining in eastern and southern Africa. However, recent incidence data are non-existent or very limited for many countries, particularly in western and central Africa.FundingNational Institute of Allergy and Infectious Diseases

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