scholarly journals Hemophagocytic Lymphohistiocytosis Secondary to Human Immunodeficiency Virus-Associated Histoplasmosis

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Anthony A. Castelli ◽  
David G. Rosenthal ◽  
Rachel Bender Ignacio ◽  
Helen Y. Chu
Keyword(s):  
Escherichia Coli ◽  
Human Immunodeficiency Virus ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Mycobacterium Avium Complex ◽  
Multiorgan Failure ◽  
Rapid Diagnosis ◽  
Disseminated Histoplasmosis ◽  
Immunodeficiency Virus ◽  
Underlying Disorder ◽  
Immunocompromised Hosts

Abstract Hemophagocytic lymphohistiocytosis (HLH) in immunocompromised hosts is a fulminant syndrome of immune activation with high rates of mortality that may be triggered by infections or immunodeficiency. Rapid diagnosis and treatment of the underlying disorder is necessary to prevent progression to multiorgan failure and death. We report a case of HLH in a patient with human immunodeficiency virus, disseminated histoplasmosis, Mycobacterium avium complex, and Escherichia coli bacteremia. We discuss management of acutely ill patients with HLH and treatment of the underlying infection versus initiation of HLH-specific chemotherapy.

HEp-2 Cell-Adherent Escherichia coli in Patients with Human Immunodeficiency Virus-Associated Diarrhea

1995 ◽  
Vol 171 (6) ◽  
pp. 1636-1639 ◽  
Author(s):  
J. J. Mathewson ◽  
Z. D. Jiang ◽  
A. Zumla ◽  
C. Chintu ◽  
N. Luo ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Human Immunodeficiency Virus ◽  
Immunodeficiency Virus

scholarly journals Membrane Relocation but Not Tight Binding of Human Immunodeficiency Virus Type 1 Gag Particles Myristoylated in Escherichia coli

Virology ◽  
2001 ◽  
Vol 283 (2) ◽  
pp. 343-352 ◽  
Author(s):  
Yuko Morikawa ◽  
Ayako Kinoshita ◽  
Toshiyuki Goto ◽  
Hiroshi Tomoda ◽  
Kouichi Sano
Keyword(s):  
Escherichia Coli ◽  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Tight Binding ◽  
Immunodeficiency Virus

scholarly journals Acute Suppurative Thyroiditis Secondary to Escherichia coli Infection

2021 ◽  
Author(s):  
Nida Siddiqui ◽  
Nikola Deletic ◽  
Frederick Raal ◽  
Farzahna Mohamed
Keyword(s):  
Escherichia Coli ◽  
Suppurative Thyroiditis ◽  
Delay In Diagnosis ◽  
E Coli ◽  
High Clinical Suspicion ◽  
Immunodeficiency Virus ◽  
Escherichia Coli Infection ◽  
Acute Suppurative Thyroiditis ◽  
Gram Negative Organisms ◽  
Immunocompromised Hosts

Infections of the thyroid gland are rare. Its innate resistance to infections can be attributed to its unique anatomical features and rich blood supply. High clinical suspicion is required as a delay in diagnosis can lead to significant morbidity and mortality. Major pathogens include the Gram-positive Staphylococcus aureus and Streptococcus species; however, Gram-negative organisms have been found especially in immunocompromised hosts. We present a rare case of acute suppurative thyroiditis (AST) secondary to Escherichia coli (E. coli) infection in a woman known to be infected with human immunodeficiency virus (HIV).

scholarly journals Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Histoplasmosis in Rheumatologic Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yael Kusne ◽  
Michael Christiansen ◽  
Christopher Conley ◽  
Juan Gea-Banacloche ◽  
Ayan Sen
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Pediatric Patients ◽  
Histoplasma Capsulatum ◽  
Hematologic Malignancies ◽  
Rapid Diagnosis ◽  
Rheumatologic Disease ◽  
Disseminated Histoplasmosis ◽  
Serious Infections ◽  
Time To Diagnosis ◽  
Prompt Diagnosis

Background. Hemophagocytic lymphohistiocytosis (HLH) was originally described in pediatric patients presenting with fever, hepatosplenomegaly, and blood cell abnormalities. Later, HLH was recognized to occur in adults, often associated with hematologic malignancies or serious infections. Conclusion. Patients presenting with HLH are critically ill, and rapid diagnosis is key. In adults, the search for the trigger must begin promptly as time to diagnosis effects survival. The underlying trigger in our patients was Histoplasma capsulatum infection, which is rare in the southwestern United States. Prompt diagnosis led to recovery in one patient, while the other did not survive.

Immunocompromised Hosts and Microorganism-Specific Syndromes

2016 ◽  
pp. 475-490
Author(s):  
Pritish K. Tosh ◽  
M. Rizwan Sohail
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex ◽  
Occupational Exposure ◽  
Male Circumcision ◽  
Hiv Transmission ◽  
Sexual Transmission ◽  
Intravenous Drug ◽  
Immunodeficiency Virus ◽  
Immunocompromised Hosts ◽  
Intravenous Drug Injection

Human immunodeficiency virus (HIV) is transmitted sexually, perinatally, through parenteral inoculation (eg, intravenous drug injection, occupational exposure), through blood products, and, less commonly, through donated organs or semen. Sexual transmission is the most common means of infection. Conditions that may increase the risk of sexually acquiring HIV infection include traumatic intercourse (ie, receptive anal), ulcerative genital infections (including syphilis, herpes simplex, and chancroid), and lack of male circumcision. The proper use of latex condoms substantially reduces the risk of HIV transmission.

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