scholarly journals Predictors of Mortality in End-Stage Renal Disease Patients With Infective Endocarditis

2015 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Rachel Powell ◽  
James P. Steinberg ◽  
Jesse T. Jacob
Lupus ◽  
2011 ◽  
Vol 20 (12) ◽  
pp. 1329-1335 ◽  
Author(s):  
H Al Durahim ◽  
G Al Ghamdi ◽  
A Al Seraya ◽  
R Alkhiari ◽  
A Al Sayyari

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0156642 ◽  
Author(s):  
Ramon A. Tamayo Isla ◽  
Oluwatoyin I. Ameh ◽  
Darlington Mapiye ◽  
Charles R. Swanepoel ◽  
Aminu K. Bello ◽  
...  

Open Medicine ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. 346-353 ◽  
Author(s):  
Aleksandra Ignjatović ◽  
Tatjana Cvetković ◽  
Radmila Pavlović ◽  
Vidojko Đorđević ◽  
Zoran Milošević ◽  
...  

AbstractThere is a higher mortality between patients with end-stage renal disease than patients in the general population. These circumstances have led to a search for risk factors as predictors of mortality in dialysis patients. Amongst those, inhibitors of the nitric-oxide (NO) synthesis deserve special attention, since patients with end-stage renal disease are also characterized by accelerated atherosclerosis. Asymmetric-dimethylarginine (ADMA) and symmetric-dimethylarginine (SDMA), as well as C-reactive protein (CRP), have also been recognized as predictors of mortality in patients on dialysis. The aim of our study was to compare the prediction power of ADMA, SDMA and CRP for all-cause mortality in patients with end stage renal disease during the fourteen month follow-up. In total 162 patients on hemodialysis were included. ADMA and SDMA were measured by the high-performance liquid chromatography (HPLC); CRP was measured using immunonephelometric assays. During the 14-month period 28 patients (34.1%) died from all-cause mortality. Using univariate analysis, hazard ratios (HR) of the potential independent predictors of mortality in hemodialysis patients were ADMA (HR 1.39 (1.01–1.91) p=0.043) and CRP (HR 1.024 (1.009–1.1.040) p=0.001). Further, multivariate analysis (MVA), however, showed that ADMA is the only predictor of all-cause mortality (HR 1.76 (1.002–3.11) P=0.049), while SDMA failed to predict death in this population. Therefore, our data shows that ADMA is an independent and better marker of all-cause mortality compared with CRP.


2004 ◽  
Vol 164 (1) ◽  
pp. 71 ◽  
Author(s):  
Christian Spies ◽  
James R. Madison ◽  
Irwin J. Schatz

2017 ◽  
Vol 12 (11) ◽  
pp. 1814-1822 ◽  
Author(s):  
Mavish S. Chaudry ◽  
Nicholas Carlson ◽  
Gunnar H. Gislason ◽  
Anne-Lise Kamper ◽  
Marianne Rix ◽  
...  

2000 ◽  
Vol 35 (6) ◽  
pp. 1052-1060 ◽  
Author(s):  
Robert L. Benz ◽  
Mark R. Pressman ◽  
Edward T. Hovick ◽  
Donald D. Peterson

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Taksaon Angsutararux ◽  
Nasikarn Angkasekwinai

Abstract Background To investigate the cumulative incidence of and factors associated with mortality among patients with infective endocarditis (IE) at Thailand’s largest national tertiary referral center. Methods Medical charts of adult patients diagnosed with IE by Duke criteria at Siriraj Hospital during January 2005 to May 2015 were retrospectively reviewed. Results Of 380 patients, 66.3% had definite IE, and 81.3% had native valve IE (NVE). Cumulative IE incidence was 5.67/1000 admissions. The most common pathogens were viridans group streptococci (VGS) (39.7%), methicillin-sensitive Staphylococcus aureus (MSSA) (13.1%), and beta-hemolytic streptococci (11.5%) in NVE; and, MSSA (20.3%), VGS (20.3%), and Enterococcus spp. (16.9%) in prosthetic valve (PVE) or device-related IE (DRIE). Overall in-hospital mortality was 18.4%. Mortality was significantly higher in PVE/DRIE than in NVE (26.8% vs. 16.5%, p = 0.047). End-stage renal disease (ESRD) (aOR: 9.43, 95% CI: 2.36–37.70), diabetes mellitus (DM) (aOR: 2.81, 95% CI: 1.06–7.49), neurological complication (aOR: 14.16, 95% CI: 5.11–39.22), congestive heart failure (aOR: 4.32, 95% CI: 1.91–9.75), hospital-acquired infection (aOR: 3.78, 95% CI: 1.66–8.57), renal complication (aOR: 3.12, 95%CI: 1.32–7.37), and other complication during admission (aOR: 3.28, 95% CI: 1.41–7.61) were independently associated with mortality. Conclusions The incidence of IE, and the mortality rate among those diagnosed with IE are both increasing in Thailand – particularly among those with PVE or DRIE. End-stage renal disease, diabetes mellitus, and development of IE-related complications during admission were found to be independent predictors of mortality.


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