scholarly journals Tool for estimating the probability of having COVID-19 with one or more negative RT-PCR results

Author(s):  
Alejandro Jara ◽  
Eduardo A Undurraga ◽  
Rafael Araos

Abstract Early case detection and isolation of infected individuals are critical to controlling COVID-19. RT-PCR is considered the gold standard for the diagnosis of SARS-CoV-2 infection, but false-negatives occur. We built a user-friendly online tool to estimate the probability of having COVID-19 with negative RT-PCR results and thus avoid preventable transmission.

2021 ◽  
Author(s):  
Alejandro Jara ◽  
Eduardo A. Undurraga ◽  
Rafael Araos

AbstractEarly case detection and isolation of infected individuals are critical to controlling COVID-19. RT-PCR is considered the diagnosis gold standard, but false-negatives occur. Based on previous work, we built a user-friendly online tool to estimate the probability of having COVID-19 with negative RT-PCR results and thus avoid preventable SARS-CoV-2 transmission.


2017 ◽  
Vol 22 (39) ◽  
Author(s):  
Clémentine Calba ◽  
Mathilde Guerbois-Galla ◽  
Florian Franke ◽  
Charles Jeannin ◽  
Michelle Auzet-Caillaud ◽  
...  

In August 2017, an autochthonous chikungunya case was reported in south-east France. By mid-September, eight additional autochthonous cases were found in the index case’s neighbourhood, where the chikungunya virus vector Aedes albopictus was observed. Genomic characterisation identified an East-Central South African (ECSA) lineage strain, probably from the Central African region and carrying an adaptive mutation facilitating transmission by Ae. albopictus. The event confirms we need early case detection and response to contain chikungunya in Europe.


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