HIV and Aging: Multimorbidity in Older People Living with HIV in One Non-Urban Southeastern Ryan White HIV/AIDS Program Clinic
Abstract Background Age-related chronic conditions are becoming more concerning for people living with HIV (PLWH). We aimed to identify characteristics associated with multimorbidity and evaluate for association between multimorbidity and HIV outcomes. Methods Cohorts included PLWH aged 45-89 with >1 medical visit at one Ryan White HIV/AIDS Program (RWHAP) Southeastern HIV clinic in 2006 (Cohort 1) or 2016 (Cohort 2). Multimorbidity was defined as >2 chronic diseases. We used multivariable logistic regression to assess for associations between characteristics and multimorbidity and between multimorbidity and HIV outcomes. Results Multimorbidity increased from Cohort 1 (n=149) to Cohort 2 (n=323) (18.8% vs 29.7%, p<0.001). Private insurance was associated with less multimorbidity than Medicare (Cohort 1: adjusted Odds Ratio [aOR] 0.15, 95% Confidence Interval [CI] 0.02-0.63; Cohort 2: aOR 0.53, 95% CI 0.27-1.00). In Cohort 2, multimorbidity was associated with female gender (aOR 2.57, 95% CI 1.22-5.58). In Cohort 1, Black participants were less likely to be engaged in care compared to non-Black participants (aOR 0.72, 95% CI 0.61-0.87) Cohort 2, participants with rural residences were more likely to be engaged in care compared to those with urban residences (aOR 1.23, 95% CI 1.10-1.38). Multimorbidity was not associated with differences in HIV outcomes. Conclusions While PLWH have access to RWHAP HIV care, PLWH with private insurance had lower rates of multimorbidity, which may reflect better access to preventative non-HIV care. In 2016, multimorbidity was higher for women. The RWHAP and RWHAP Part D could invest in addressing these disparities related to insurance and gender.