scholarly journals Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient

2020 ◽  
Vol 7 (7) ◽  
Author(s):  
Caitlin A Trottier ◽  
Vimal V Jhaveri ◽  
Mary Jane Zimarowski ◽  
Barbra M Blair ◽  
Carolyn D Alonso

Abstract Superficial dermatophyte infections are common in the general population and are readily treated with topical antifungals. Deeper invasion is rare, and dissemination to visceral organs is extremely uncommon. We describe a 66-year-old renal transplant recipient who developed disseminated Trichophyton rubrum infection while undergoing treatment for acute humoral rejection. The infection presented as a facial rash with subsequent dissemination to the lungs and chest wall. All sites of infection improved with combination administration of oral posaconazole and terbinafine. In this work, we review the available literature regarding management of disseminated Trichophyton infection and discuss therapeutic interventions for disseminated dermatophytosis in immunosuppressed hosts.

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Yan Jun Li ◽  
Amila Rohan Siriwardana ◽  
James Lawrence Penn Symons ◽  
Gordon Francis O’Neill ◽  
Min Ru Qiu ◽  
...  

Leiomyomas are smooth muscle tumours that are rarely found in the kidney. There is one report of a leiomyoma in a kidney transplant in a paediatric recipient. Here, we report an adult renal transplant recipient who developed an Epstein-Barr virus-positive leiomyoma in his allograft 15 years after transplantation. The patient was converted to everolimus for posttransplant immunosuppression management and there was no sign of progression over a year.


2020 ◽  
Vol 8 ◽  
pp. 2050313X2095303
Author(s):  
Camille Pennou ◽  
Eileen Javidi ◽  
Julie Lecours ◽  
Annie Bélisle ◽  
Sandra Davar

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa–associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.


2021 ◽  
Author(s):  
Gang Fang ◽  
Ning-Chang Cheng ◽  
Li-Li Huang ◽  
Wei-Ping Xie ◽  
Chun-Mei Hu ◽  
...  

Abstract Background Along with the medical development, organ transplant patients increase dramatically. Since these transplant patients take immunosuppressants for a long term, their immune functions are in a suppressed state, prone to all kinds of opportunistic infections and cancer. However, it is rarely reported that the kidney transplant recipient (KTR) had pulmonary tuberculosis and lung cancer simultaneously. Case presentations: A 60-year-old male was admitted because of persistent lung shadow for two years without any obvious symptom eight years after renal transplant. T-SPOT test was positive but other etiological examinations for Mycobacterium tuberculosis were negative. Chest CT scan revealed two pulmonary lesions in the right upper and lower lobe. 18F-fluorodesoxyglucose positron-emission tomography (FDG-PET) CT found FDG intake increased in both pulmonary consolidation lesions. CT-guided percutaneous transthoracic needle biopsy revealed lung adenocarcinoma and tuberculosis. The video-assisted thoracoscopic surgery was operated to resect the malignancy lesions. The patient received specific anti-tuberculosis therapy and was discharged. At the follow-up of 6 months post drug withdrawal, the patient was recovered very well. Conclusion We for the first time reported co-existence of culture-negative pulmonary TB and lung adenocarcinoma in a KTR, which highlighted the clinical awareness of co-occurrence of TB and malignancy after renal transplant and emphasized the value of biopsy and 18F-FDG-PET in early diagnosis of TB and cancer.


2020 ◽  
pp. 1-3
Author(s):  
Nizar Attallah ◽  
Ammar Abdulbaki ◽  
Nizar Attallah ◽  
Rakesh Madhyastha ◽  
Sudeendra Gupta

Hormonal abnormalities that are associated with advanced kidney failure normally reverses after kidney transplantation. This usually helps to normalize menstrual cycles for female patients and helps improve fertility. Post-transplant gynaecological disorders are under-reported in general. We present a patient who developed endometriosis after second kidney transplant. She was treated with surgery followed by hormonal therapy. We discuss the pathophysiology of endometriosis and possible relation to the immune system.


2005 ◽  
Vol 6 (3) ◽  
pp. 127-133 ◽  
Author(s):  
Daniel Humberto Pozza ◽  
Livia Prates Soares ◽  
Löonilson Gaião de Melo ◽  
Antönio L.B. Pinheiro ◽  
Marilia Gerhardt de Oliveira

Abstract Salivary dysfunction may be due to systemic diseases and medications. The development of sialoliths is a multifactorial event in which disturbances in secretion, microliths, and bacteria may play a major role. A case of sialolith in the submandibular gland of a 58-year old woman, with a medical history of renal failure end kidney transplant, is reported. Citation Soares LP, Gaião de Melo L, Pozza DH, Pinheiro ALB, Gerhardt de Oliveira M. Submandibular Gland Sialolith in a Renal Transplant Recipient: A Case Report. J Contemp Dent Pract 2005 August;(6)3:127-133.


2020 ◽  
Vol 8 (01) ◽  
pp. 12-16 ◽  
Author(s):  
Mohammad Abuzeineh ◽  
Ahmad Ziadeh ◽  
Taba Kheradmand ◽  
Van Nguyen ◽  
Preethi Yerram

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