scholarly journals A case report: a patient with IgA nephropathy and coeliac disease. Complete clinical remission following gluten-free diet

2009 ◽  
Vol 2 (2) ◽  
pp. 161-163
Author(s):  
N. Koivuviita ◽  
R. Tertti ◽  
M. Heiro ◽  
K. Metsarinne
Keyword(s):  
Case Report ◽  
Coeliac Disease ◽  
Iga Nephropathy ◽  
Clinical Remission ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Complete Clinical Remission

scholarly journals MODERN RESOURCES OF CELIAC DISEASE TREATMENT EFFECTIVENESS IMPROVEMENT

2020 ◽  
Vol 16 (3) ◽  
pp. 33-38
Author(s):  
O.Yu. Gubska ◽  
Yu.V. Chichula ◽  
A.K. Sizenko ◽  
L.M. Kupchik
Keyword(s):  
Small Intestine ◽  
Celiac Disease ◽  
Clinical Remission ◽  
Clinical Symptoms ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Breath Tests ◽  
Complete Clinical Remission ◽  
Comprehensive Examination ◽  
Hydrogen Breath Tests

Relevance. Although monotherapy with a gluten-free diet (BGD) for celiac disease is highly effective, it does not in all cases achieve complete remission of the disease. Therefore, an additional comprehensive examination of patients for the purpose of prescribing reasonable therapy is relevant. Objective: to study the causes of the persistence of clinical symptoms in patients with celiac disease who are on a gluten-free diet for 6 months. Materials and methods. Patients with celiac disease (n = 41) who were on a gluten-free diet (GFD) for 6 months were studied. The average age is 35.42 ± 0.45 years. Group 1 (n = 17) – patients who subjectively noted a positive dynamics of treatment and with a significant improvement in general condition, but without complete clinical remission. Group 2 (n = 24) – patients with unsatisfactory treatment results, no clinical effect from treatment, or weak positive dynamics on the background of GFD. The study included two stages: 1) assessment of patients' compliance and their diet (through the analysis of food diaries) in order to identify disorders of a gluten-free diet as the main cause of the persistence of clinical symptoms; 2) identification of other causes of the persistence of symptoms: exocrine pancreas insufficiency (EPI), lactase deficiency (LD) and the syndrome of increase bacterial growth (SIBR). A C13 triglyceride breath test (IRIS analyzer) was performed to diagnose EPI. To diagnose LD and SIBR in the small intestine, hydrogen breath tests (Micro H2-meter analyzer) were used – a test with lactose and D-xylose, respectively. Also, the titer of antibodies to tissue transglutaminase (TTG) to deaminated gliadin peptides (DPG) was determined in all patients, and their DPG/TTG ratio was calculated. Results. The main reason for the ineffectiveness of treatment is a violation of a gluten-free diet, found in 63.4% of subjects (incompletely formed mushy stool, polyfaeces, steatorrhea; recurrent abdominal pain, bloating, flatulence). Revision of food intake and elimination of sources of latent gluten from the diet of patients with celiac disease allowed to achieve complete serological remission (normalization of titers specific for celiac disease antibodies) in all patients, but complete clinical remission was achieved in only 34.6%. Therefore, it is concluded that there are other causes of incomplete remission of celiac disease associated with concomitant diseases of the digestive tract. Using carbon and hydrogen breath tests, it was found that, in addition to diet, the reasons for the lack of complete remission in patients with celiac disease are EPI (19%), SIBR in the small intestine (16%), LD (47%) and a combination of EPI with SIBR. Conclusion. The inclusion of respiratory tests (C13-triglyceride, hydrogen with lactose, and D-xylose) in a comprehensive examination of patients with celiac disease can significantly improve treatment outcomes and reduce the duration of clinical remission.

scholarly journals Adding Water to the Mill: Olmesartan-Induced Collagenous Sprue—A Case Report and Brief Literature Review

2016 ◽  
Vol 2016 ◽  
pp. 1-2 ◽  
Author(s):  
Claudine Desruisseaux ◽  
Michaël Bensoussan ◽  
Etienne Désilets ◽  
Hanh-Khiem Tran ◽  
Robert Arcand ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Clinical Remission ◽  
Poor Prognosis ◽  
Significant Proportion ◽  
Rare Condition ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Unique Case

Collagenous sprue (CS) is a distinct clinicopathological disorder histologically defined by a thickened subepithelial band (Freeman, 2011). It is a rare condition which has been recently observed in a significant proportion of sprue-like enteropathy associated with olmesartan, a novel entity described by Rubio-Tapia et al. in 2012. CS is historically associated with a poor prognosis (Marthey et al., 2014). However, histological and clinical improvements have been described in most studies with concomitant usage of corticosteroids and/or gluten-free diet (Marthey et al., 2014). We report a unique case of olmesartan-induced collagenous sprue in a 79-year-old man that showed complete histological and clinical remission with the sole withdrawal of the incriminating drug. The literature on this topic is briefly reviewed.

scholarly journals Cystic fibrosis and coeliac disease: a case report of an unusual association

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Leen Jamel Doya ◽  
Naya Talal Hassan ◽  
Narmin Hajo ◽  
Fareeda Wasfy Bijow ◽  
Alexander Ibrahim ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Case Report ◽  
Coeliac Disease ◽  
Failure To Thrive ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Intestinal Malabsorption ◽  
Unusual Association ◽  
Common Causes

ABSTRACT Coeliac disease (CD) and cystic fibrosis (CF) are well known as the most common causes of chronic intestinal malabsorption in childhood. The coexistence of coeliac disease with cystic fibrosis is uncommon. Here, we describe the case of cystic fibrosis in a patient diagnosed with coeliac disease who failed to respond clinically to a gluten-free diet and had persistent steatorrhea and failure to thrive.

scholarly journals Pernio as the clinical presentation of celiac disease: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2094044
Author(s):  
Alexandre Lemieux ◽  
Natasha Emily Sanchez Vivas ◽  
Julie Powell ◽  
Prévost Jantchou ◽  
Marie-Paule Morin
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Pharmacological Treatment ◽  
Clinical Remission ◽  
Clinical Presentation ◽  
Gastrointestinal Symptoms ◽  
Skin Lesions ◽  
Gluten Free Diet ◽  
Gluten Free

We present the case of a 12-year-old girl with severe pernio as the sole clinical presentation of celiac disease (CD), without associated gastrointestinal symptoms. Lesions greatly improved once a gluten free diet was initiated. At 5-year follow-up, she remains in clinical remission throughout the year with no pharmacological treatment, without skin lesions flare-up in the winter months.

scholarly journals A fatal outcome in a patient with coeliac disease who suspended a strict gluten-free diet: a case report

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110610
Author(s):  
Chong Lu ◽  
Xiao-Juan Zheng ◽  
Hong-Jun Hua ◽  
Qun-Ying Wang
Keyword(s):  
Case Report ◽  
Coeliac Disease ◽  
Fatal Outcome ◽  
Primary Treatment ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Immunological Reaction ◽  
Small Bowel Disease ◽  
Haemophagocytic Lymphohistiocytosis

Coeliac disease (CD) is an autoimmune small bowel disease that occurs in susceptible individuals that develop an immunological reaction to gluten. A strict gluten-free diet (GFD) is the primary treatment for CD. This case report describes a patient with CD recurrence due to a discontinuation of a strict GFD by the patient. After recurrence, the patient developed fever and pancytopaenia, and quickly died of haemophagocytic lymphohistiocytosis (HLH). To the best of our knowledge, this is the first description of a case of CD associated with HLH due to discontinued GFD, which may contribute to improving the awareness of the importance of maintaining a strict GFD and having regular follow-up examinations.

Micronutrient deficiencies in children with coeliac disease; a double-edged sword of both untreated disease and treatment with gluten-free diet

2021 ◽  
Author(s):  
Lorcan McGrogan ◽  
Mary Mackinder ◽  
Fiona Stefanowicz ◽  
Maria Aroutiounova ◽  
Anthony Catchpole ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Micronutrient Deficiencies
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