scholarly journals Association of serum albumin levels with kidney function decline and incident chronic kidney disease in elders

2017 ◽  
Vol 33 (6) ◽  
pp. 986-992 ◽  
Author(s):  
Joshua Lang ◽  
Ronit Katz ◽  
Joachim H Ix ◽  
Orlando M Gutierrez ◽  
Carmen A Peralta ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Albumin ◽  
Kidney Function ◽  
Incident Chronic Kidney Disease ◽  
Kidney Function Decline

scholarly journals Metabolites associate with kidney function decline and incident chronic kidney disease in the general population

2013 ◽  
Vol 28 (8) ◽  
pp. 2131-2138 ◽  
Author(s):  
Oemer-Necmi Goek ◽  
Cornelia Prehn ◽  
Peggy Sekula ◽  
Werner Römisch-Margl ◽  
Angela Döring ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
General Population ◽  
Kidney Function ◽  
Incident Chronic Kidney Disease ◽  
Kidney Function Decline

scholarly journals Incident chronic kidney disease and the rate of kidney function decline in individuals with hypertension

2009 ◽  
Vol 25 (3) ◽  
pp. 801-807 ◽  
Author(s):  
R. Hanratty ◽  
M. Chonchol ◽  
L. Miriam Dickinson ◽  
B. L. Beaty ◽  
R. O. Estacio ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Function ◽  
Incident Chronic Kidney Disease ◽  
Kidney Function Decline

scholarly journals Kidney function and symptom development over time in elderly patients with advanced chronic kidney disease: results of the EQUAL cohort study

2020 ◽  
Author(s):  
Cynthia J Janmaat ◽  
Merel van Diepen ◽  
Yvette Meuleman ◽  
Nicholas C Chesnaye ◽  
Christiane Drechsler ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Cohort Study ◽  
Kidney Disease ◽  
Kidney Function ◽  
Symptom Severity ◽  
Clinical Decision Making ◽  
Symptom Development ◽  
Symptom Index ◽  
The Mean ◽  
Kidney Function Decline

Abstract Background Initiation of renal replacement therapy often results from a combination of kidney function deterioration and symptoms related to chronic kidney disease (CKD) progression. We investigated the association between kidney function decline and symptom development in patients with advanced CKD. Methods In the European Quality study on treatment in advanced CKD (EQUAL study), a European prospective cohort study, patients with advanced CKD aged ≥65 years and a kidney function that dropped <20 mL/min/1.73 m2 were followed for 1 year. Linear mixed-effects models were used to assess the association between kidney function decline and symptom development. The sum score for symptom number ranged from 0 to 33 and for overall symptom severity from 0 to 165, using the Dialysis Symptom Index. Results At least one kidney function estimate with symptom number or overall symptom severity was available for 1109 and 1019 patients, respectively. The mean (95% confidence interval) annual kidney function decline was 1.70 (1.32; 2.08) mL/min/1.73 m2. The mean overall increase in symptom number and severity was 0.73 (0.28; 1.19) and 2.93 (1.34; 4.52) per year, respectively. A cross-sectional association between the level of kidney function and symptoms was lacking. Furthermore, kidney function at cohort entry was not associated with symptom development. However, each mL/min/1.73 m2 of annual kidney function decline was associated with an extra annual increase of 0.23 (0.07; 0.39) in the number of symptoms and 0.87 (0.35; 1.40) in overall symptom severity. Conclusions A faster kidney function decline was associated with a steeper increase in both symptom number and severity. Considering the modest association, our results seem to suggest that repeated thorough assessment of symptom development during outpatient clinic visits, in addition to the monitoring of kidney function decline, is important for clinical decision-making.

scholarly journals Optimism is associated with chronic kidney disease and rapid kidney function decline among African Americans in the Jackson Heart Study

2020 ◽  
Vol 139 ◽  
pp. 110267
Author(s):  
LáShauntá M. Glover ◽  
Crystal Butler-Williams ◽  
Loretta Cain-Shields ◽  
Allana T. Forde ◽  
Tanjala S. Purnell ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
African Americans ◽  
Kidney Disease ◽  
Kidney Function ◽  
Jackson Heart Study ◽  
Heart Study ◽  
Kidney Function Decline

scholarly journals Serum Uric Acid Levels and Incident Chronic Kidney Disease in Patients With Type 2 Diabetes and Preserved Kidney Function

Diabetes Care ◽  
2011 ◽  
Vol 35 (1) ◽  
pp. 99-104 ◽  
Author(s):  
G. Zoppini ◽  
G. Targher ◽  
M. Chonchol ◽  
V. Ortalda ◽  
C. Abaterusso ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Uric Acid ◽  
Kidney Disease ◽  
Serum Uric Acid ◽  
Kidney Function ◽  
Incident Chronic Kidney Disease

scholarly journals Lifetime Cocaine and Opiate Use and Chronic Kidney Disease

2016 ◽  
Vol 44 (6) ◽  
pp. 447-453 ◽  
Author(s):  
Tessa Novick ◽  
Yang Liu ◽  
Anika Alvanzo ◽  
Alan B. Zonderman ◽  
Michele K. Evans ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Function ◽  
Healthy Aging ◽  
Illicit Drugs ◽  
Community Dwelling ◽  
Rapid Decline ◽  
Cocaine Use ◽  
Opiate Use ◽  
Kidney Function Decline

Background: More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association of lifetime opiate and cocaine use with reduced kidney function, albuminuria and rapid kidney function decline among urban-dwelling adults. Methods: Our prospective cohort included 2,286 Healthy Aging in Neighborhoods of Diversity across the Life Span study participants who were community-dwelling adults residing in Baltimore, MD. The predictive variables were lifetime opiate and cocaine use, defined as use of opiates or crack/cocaine ≥5 times. Outcomes included prevalent reduced estimated glomerular filtration rate (eGFR; <60 ml/min/1.73 m2 by Chronic Kidney Disease (CKD)-Epidemiology Collaboration), albuminuria (albumin-to-creatinine ratio >30 mg/g, n = 1,652) and rapid kidney function decline (>3 ml/min/1.73 m2 per year over a median of 4.7 years, n = 1,660). Results: Participants' mean age was 48 years, 15% reported opiate use, and 22% reported cocaine use. A total of 115 (5.0%) participants had reduced eGFR, 190 (11.5%) had albuminuria and 230 (13.8%) experienced rapid decline in kidney function. In adjusted logistic regression analyses, both substances were associated with greater odds of reduced eGFR (OR 2.71, 95% CI 1.50-4.89 for opiates; OR 1.40, 95% CI 0.87-2.24 for cocaine). Both substances were associated with greater odds of albuminuria (OR 1.20, 95% CI 0.83-1.73 for opiates; OR 1.80, 95% CI 1.29-2.51 for cocaine). Neither substance was associated with the rapid decline of kidney function. Conclusions: Lifetime opiate and cocaine use was associated with prevalent reduced eGFR and albuminuria, yet not with rapid kidney function decline. The use of opiate and cocaine may be an important risk factor for CKD in urban populations.

scholarly journals Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study

2018 ◽  
Vol 71 (5) ◽  
pp. 648-656 ◽  
Author(s):  
Elaine Ku ◽  
Joel D. Kopple ◽  
Charles E. McCulloch ◽  
Bradley A. Warady ◽  
Susan L. Furth ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Weight Loss ◽  
Cohort Study ◽  
Kidney Disease ◽  
Kidney Function ◽  
Kidney Function Decline

scholarly journals Gambaran kadar albumin serum pada pasien penyakit ginjal kronik stadium 5 non dialisis

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Tiffany D. Putri ◽  
Arthur E. Mongan ◽  
Maya F. Memah
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Albumin ◽  
Kidney Function ◽  
Kidney Failure ◽  
Albumin Level ◽  
Cross Sectional ◽  
Probability Sampling ◽  
Low Level ◽  
Normal Albumin

Abstract: Chronic kidney disease is a pathophysiology process with diverse etiology, causing a progressive decline on kidney function, and in most cases ends with kidney failure (stage 5). The low level of albumin serum is an important predictor of the morbidity and mortality, as a low albumin level is indicating the weak immunity and vitality in kidney failure patients. This is caused by an increase on inflammation and deficiency of protein intake. The low level of albumin serum is also a major indicator which can be used to show a person’s kidney function. Hypoalbuminemia occurred if blood albumin level is less than 3,5 g/dL. Research objective: To find out the description of albumin serum level on non-dialysis chronic kidney disease patients. Research method: Cross sectional descriptive, to obtain the data of albumin serum on non-dialysis chronic kidney disease patients carried out on December 2015 – January 2016 at two hospitals, which are RSUP. Prof. Dr. R. D. Kandou Manado and Rumah Sakit Advent Manado. The research sample were the blood sample from 35 people suffering a stage five non dialysis chronic kidney disease, which determined by consecutive sampling from non-probability sampling model. Result: According to the laboratory result, from the 35 patients diagnosed with a stage five non dialysis chronic kidney disease, 16 patients are having a decrease on albumin serum (45.7%), and 19 patients are having a normal albumin level (54.4%). None of the samples are having an increase on albumin level. Conclusion: From the research it can be concluded that there are more patients with normal albumin level which is 29 people (54.5%) compared to the patients with hypoalbuminemia which is 16 people (45.7%), with male having a higher tendency of prevalence compared to female on each category of albumin serum checkup.Keywords: albumin serum, stage five chronic kidney disease, non-dialysis.Abstrak: Penyakit ginjal kronik adalah suatu proses patofisiologi dengan etiologi yang beragam, mengakibatkan penurunan fungsi ginjal yang progresif, dan pada umumnya berakhir dengan gagal ginjal (stadium 5). Kadar serum albumin rendah merupakan prediktor penting dari mordibitas dan mortalitas karena rendahnya serum albumin pada pasien gagal ginjal menggambarkan rendahnya ketahanan dan daya hidup pasien gagal ginjal terminal. Hal ini disebabkan adanya peningkatan inflamasi dan kekurangan asupan protein pada penderita. Rendahnya serum albumin juga salah satu penanda penting yang dapat digunakan untuk menunjukan fungsi ginjal dari seseorang. Dikatakan hipoalbuminemia jika kadar albumin darah kurang dari 3,5 g/dL. Tujuan Penelitian: untuk mengetahui gambaran kadar albumin serum pada pasien penyakit ginjal kronik stadium 5 non dialisis. Metode Penelitan: deskriptif cross sectional, untuk mendapatkan data tentang kadar albumin serum pada pasien penyakit ginjal kronik stadium 5 non dialisis yang dilakukan sejak Desember 2015-Januari 2016 di dua rumah sakit yaitu RSUP. Prof. Dr. R. D. Kandou Manado dan Rumah Sakit Advent Manado. Sampel penelitian adalah sampel darah dari 35 orang yang menderita penyakit ginjal kronik stadium 5 non dialisis ditentukan dengan cara non-probability sampling jenis consecutive. Hasil: Berdasarkan hasil pemeriksaan laboratorium yang dilakukan, terdapat 35 pasien yang terdiagnosis penyakit ginjal kronik stadium 5 non dialisis didapatkan bahwa 16 pasien mengalami penurunan kadar albumin serum (45.7%), 19 orang memiliki kadar albumin dalam batas normal (54.3%) dan tidak terdapat peningkatan kadar albumin sama sekali pada pasien yang dilakukan penelitian. Simpulan: Dari hasil penelitian dapat disimpulkan bahwa kadar albumin serum pada pasien dengan kadar albumin yang masih dalam batas normal yaitu sebanyak 19 orang (54.3%) lebih banyak dibandingkan dengan hipoalbuminemia yaitu sebanyak 16 orang (45.7%) dimana jenis kelamin laki-laki cenderung lebih tinggi prevalensinya dibandingkan dengan perempuan pada tiap kategori hasil pemeriksaan kadar albumin serum.Kata kunci: albumin serum, penyakit ginjal kronik stadium 5, non dialisis.

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