scholarly journals Association between the body mass index and chronic kidney disease in men and women. A population-based study from Israel

2013 ◽  
Vol 28 (suppl 4) ◽  
pp. iv130-iv135 ◽  
Author(s):  
E. Cohen ◽  
A. Fraser ◽  
E. Goldberg ◽  
G. Milo ◽  
M. Garty ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yusaku Hashimoto ◽  
Takahiro Imaizumi ◽  
Sawako Kato ◽  
Yoshinari Yasuda ◽  
Takuji Ishimoto ◽  
...  

AbstractThe influence of body mass or metabolic capacity on the association between alcohol consumption and lower risks of developing chronic kidney disease (CKD) is not fully elucidated. We examined whether the body mass index (BMI) affects the association between drinking alcohol and CKD. We defined CKD as an estimated glomerular filtration rate decline < 60 mL/min/1.73 m2 and/or positive proteinuria (≥ 1+). Participants were 11,175 Japanese individuals aged 40–74 years without baseline CKD who underwent annual health checkups. Daily alcohol consumption at baseline was estimated using a questionnaire, and the participants were categorized as “infrequent (occasionally, rarely or never),” “light (< 20 g/day),” “moderate (20–39 g/day),” and “heavy (≥ 40 g/day).” Over a median 5-year observation period, 936 participants developed CKD. Compared with infrequent drinkers, light drinkers were associated with low CKD risks; adjusted hazard ratios (95% confidence intervals) were 0.81 (0.69–0.95). Stratified by BMI (kg/m2), moderate drinkers in the low (< 18.5), normal (18.5–24.9), and high (≥ 25.0) BMI groups had adjusted hazard ratios (95% confidence intervals) of 3.44 (1.60–7.42), 0.75 (0.58–0.98), and 0.63 (0.39–1.04), respectively. Taken together, the association between alcohol consumption and CKD incidence was not the same in all the individuals, and individual tolerance must be considered.


Cancer ◽  
2017 ◽  
Vol 123 (20) ◽  
pp. 4022-4030 ◽  
Author(s):  
Zohar Levi ◽  
Jeremy D. Kark ◽  
Lior H. Katz ◽  
Gilad Twig ◽  
Estela Derazne ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1511-P
Author(s):  
DAISUKE MATSUTANI ◽  
SOICHIRO MINATO ◽  
YUKI TSUJIMOTO ◽  
HIROSHI MAEGAWA ◽  
MASAYA SAKAMOTO

2021 ◽  
Author(s):  
Yusaku Hashimoto ◽  
Sawako Kato ◽  
Yoshinari Yasuda ◽  
Takuji Ishimoto ◽  
Hiroaki Kawashiri ◽  
...  

Abstract Although previous studies demonstrated that alcohol consumption is associated with low chronic kidney disease (CKD) risk, they did not consider individual body mass and metabolic capacity. We examined whether the body mass index (BMI) affects the association between drinking and CKD. We defined CKD as an estimated glomerular filtration rate decline < 60 mL/min/1.73 m2 and/or dipstick proteinuria (≥ 1+). Participants were 11,175 Japanese individuals aged 40–74 years without baseline CKD who underwent annual health checkups. Daily alcohol consumption was estimated from a questionnaire, and the participants were categorized as "infrequent drinkers," "light drinkers (< 20 g/day)," "moderate drinkers (20–40 g/day)," and "heavy drinkers (≥ 40 g/day)." Over a median 5-year observation period, 936 participants developed CKD. Cox proportional hazards models revealed that light drinkers had a significantly reduced risk of CKD compared with infrequent drinkers (P = 0.01). Stratified by BMI, the low BMI (< 18.5 kg/m2) group had an increased risk of CKD even in light drinkers, while the high BMI (≥ 25.0 kg/m2) group had a decreased risk of CKD regardless of alcohol consumption. Taken together, alcohol consumption did not reduce the CKD risk in all populations; individual tolerance must be considered.


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