scholarly journals Long-term follow-up after rituximab for steroid-dependent idiopathic nephrotic syndrome

2011 ◽  
Vol 27 (5) ◽  
pp. 1910-1915 ◽  
Author(s):  
M. J. Kemper ◽  
J. Gellermann ◽  
S. Habbig ◽  
R. T. Krmar ◽  
K. Dittrich ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Idiopathic Nephrotic Syndrome ◽  
Steroid Dependent ◽  
Long Term Follow Up

scholarly journals LONG-TERM FOLLOW-UP STUDY OF IDIOPATHIC NEPHROTIC SYNDROME (INS) IN CHILDHOOD

1980 ◽  
Vol 14 (8) ◽  
pp. 1001-1001
Author(s):  
S Fujisawa ◽  
R Miyazaki ◽  
K Okuhara ◽  
F Suehiro ◽  
Y Watanabe ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Idiopathic Nephrotic Syndrome ◽  
Follow Up Study ◽  
Long Term Follow Up

Long-term follow-up after cyclophosphamide and cyclosporine-A therapy in steroid-dependent and -resistant nephrotic syndrome

2008 ◽  
Vol 23 (7) ◽  
pp. 1085-1092 ◽  
Author(s):  
Viktória Sümegi ◽  
Ibolya Haszon ◽  
Csaba Bereczki ◽  
Ferenc Papp ◽  
Sándor Túri
Keyword(s):  
Nephrotic Syndrome ◽  
Cyclosporine A ◽  
Steroid Dependent ◽  
Long Term Follow Up

Long-term follow-up after cyclophosphamide therapy in steroid-dependent nephrotic syndrome

2011 ◽  
Vol 26 (6) ◽  
pp. 915-920 ◽  
Author(s):  
Alberto Zagury ◽  
Anne Louise de Oliveira ◽  
Carlos Augusto Pinheiro de Moraes ◽  
Jose Augusto de Araujo Montalvão ◽  
Regina Helena Leite Lemos Novaes ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Cyclophosphamide Therapy ◽  
Steroid Dependent ◽  
Long Term Follow Up ◽  
Steroid Dependent Nephrotic Syndrome

scholarly journals Steroid-resistant idiopathic nephrotic syndrome in children: long-term follow-up and risk factors for end-stage renal disease

2013 ◽  
Vol 35 (3) ◽  
pp. 191-199 ◽  
Author(s):  
Alberto Zagury ◽  
Anne Louise de Oliveira ◽  
Jose Augusto Araujo Montalvão ◽  
Regina Helena Leite Novaes ◽  
Vinicius Martins de Sá ◽  
...  
Keyword(s):  
Risk Factors ◽  
Nephrotic Syndrome ◽  
End Stage Renal Disease ◽  
Idiopathic Nephrotic Syndrome ◽  
Steroid Resistant ◽  
Long Term Follow Up ◽  
Stage Renal Disease ◽  
End Stage

MO291RITUXIMAB IS EFFECTIVE AND SAFE IN ADULTS WITH STEROID-DEPENDENT NEPHROTIC SYNDROME: A LONG-TERM, SINGLE-CENTER EXPERIENCE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Gemma Patella ◽  
Alessandro Comi ◽  
Giuseppe Coppolino ◽  
Nicolino Comi ◽  
Giorgio Fuiano ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Case Series ◽  
Adult Patients ◽  
Single Center ◽  
Single Center Experience ◽  
Steroid Dependent ◽  
The Mean ◽  
Steroid Dependent Nephrotic Syndrome

Abstract Background and Aims Steroid-dependent nephrotic syndrome (SDNS) may require a prolonged multi-drug therapy with risk of drug toxicity and renal failure. Rituximab (RTX) treatment has been found to be helpful in reducing the steroid dosage and the need for immunosuppressants (ISs), but little data are currently available regarding very long-term outcomes in adults. We herein describe a long-term, single-center experience of RTX use in a large series of adults with SDNS. Method We studied 23 adult patients with SDNS (mean age 54.2±17.1 y; 65% male; BMI 28.5±4.7), mostly consequent to membranous (47.8%) or focal glomerulonephritis (30.2 %) who were eligible to start a RTX regimen. Before entering the RTX protocol, proteinuria and eGFR were 7.06±3.87 g/24h and 65.9±28.2 ml/min/1.73 m2, respectively; albumin and CD19/CD20 ratio were 2.9±0.9 g/L and 0.99±0.01 respectively; the mean number of ISs was 2.39±0.89 and the mean annual rate of relapses was 2.2±0.9. Results Patients were followed over a mean follow-up of 64 months (range: 12-144). After RTX (mean dose: 1202.1±372.4 mg) the rate of relapses was virtually nullified (p<0.001). eGFR remained roughly stable (62.1±19.8 ml/min/1.73 m2, p=NS), while proteinuria, albumin, CD19/CD20 and BMI all significantly improved (p ranging from 0.01 to 0.001). The mean number of additional ISs was also reduced (0.44±0.12; p<0.001) and RTX enabled discontinuation of steroids in 13/23 (56.5%) patients. No major adverse events related to therapy were recorded. Conclusion Findings from this large case-series with a remarkable very long follow-up reinforce the role of RTX as an efficient and safe weapon to improve outcomes in adult patients suffering from SDNS.

Long-Term Follow-Up of Leukocyte Adsorptive Apheresis (LAA) Treatment in Patients (PTS) with Moderately Active Steroid-Dependent Ulcerative Colitis (UC)

2005 ◽  
Vol 61 (5) ◽  
pp. AB259
Author(s):  
Robert Loefberg ◽  
Axel Dignass ◽  
Norbert Hittel ◽  
Alberto Malesci ◽  
Joachim Moessner ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Steroid Dependent ◽  
Adsorptive Apheresis ◽  
Long Term Follow Up

921 Long Term Follow-Up of a Cohort of Steroid-Dependent Crohn's Disease Patients Included in a Randomized Trial Evaluating Short Term Infliximab Combined with Azathioprine

2008 ◽  
Vol 134 (4) ◽  
pp. A-134 ◽  
Author(s):  
Laurent Costes ◽  
Jean-Frédéric Colombel ◽  
Jean-Yves Mary ◽  
Bernard Duclos ◽  
Michel Veyrac ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Randomized Trial ◽  
Short Term ◽  
Steroid Dependent ◽  
Long Term Follow Up

scholarly journals Adult–onset minimal change nephrotic syndrome: A long–term follow–up

1986 ◽  
Vol 29 (6) ◽  
pp. 1215-1223 ◽  
Author(s):  
Fernando Nolasco ◽  
J. Stewart Cameron ◽  
E.F. Heywood ◽  
Jackie Hicks ◽  
Chisholm Ogg ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Adult Onset ◽  
Long Term Follow Up
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