scholarly journals Prevalence and risk factors of chronic kidney disease in the Thai adult population: Thai SEEK study

2009 ◽  
Vol 25 (5) ◽  
pp. 1567-1575 ◽  
Author(s):  
A. Ingsathit ◽  
A. Thakkinstian ◽  
A. Chaiprasert ◽  
P. Sangthawan ◽  
P. Gojaseni ◽  
...  
BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040444
Author(s):  
Jennifer Bragg-Gresham ◽  
JS Thakur ◽  
Gursimer Jeet ◽  
Sanjay Jain ◽  
Arnab Pal ◽  
...  

ObjectivesIndia is witnessing a disturbing growth in non-communicable diseases (NCDs), including chronic kidney disease (CKD). Recently, a WHO STEPS survey was conducted in the state of Punjab, India to collect data from the adult population on NCD risk factors. We sought to compare the prevalence of CKD and its risk factors between this large state in northern India and the USA.SettingSamples were drawn from both locations, Punjab, India and the USA, using multistage stratified sampling designs to collect data representative of the general population.ParticipantsData from 2002 participants in the Punjab survey (2014–2015) and 5057 in the USA (National Health and Nutrition Examination Survey (NHANES; 2013–2014), between the ages of 18–69 years were examined.Primary and secondary outcome measuresModified Poisson regression was employed to compare prevalence between the two samples for markers of CKD and its risk factors. All analyses used sampling weights.ResultsThe average age in the Punjab sample was significantly lower than the USA (38.3 vs 42.5 years, p<0.0001). While smoking and obesity were higher in the USA, hypertension was much more common in Punjab (48.2% vs 33.4%, p<0.0001). Significant differences were seen in the prevalence of CKD, with lower prevalence of eGFR <60 mL/min/1.73 m2 (2.0% vs 3.8%, p<0.0001), but markedly higher prevalence of albuminuria (46.7% vs 8.9%, p<0.0001) in Punjab. These differences could not be explained by traditional risk factors such as diabetes and hypertension.ConclusionsWe report a strikingly high prevalence of albuminuria in Punjab, India, compared with the USA. This requires further study and may have enormous public health implications for future burden of progressive CKD, end-stage kidney disease, morbidity, mortality and specifically for elevated risk or presence of cardiovascular disease in the northern state of Punjab, India.Funding came from the National Health Mission, Punjab, India, JST and the Centers for Disease Control and Prevention, Atlanta, Georgia, USA.


2020 ◽  
Vol 5 (1) ◽  
pp. e10-e10
Author(s):  
Zebunnesa Zeba ◽  
Kaniz Fatema ◽  
Ahmed Faisal Sumit ◽  
Rahelee Zinnat ◽  
Liaquat Ali

Introduction: Early identification of chronic kidney disease (CKD) provides valuable opportunities for effective interventions that reduce the risk of outcomes, particularly renal failure. Objectives: This study aimed to screen the Bangladeshi asymptomatic adult population for CKD to identify potential risk factors for its development. Patients and Methods: The screening program was carried out among the 400 subjects in the Thakurgaon district of Bangladesh to identify people with the risk of CKD. All the subjects were asymptomatic and previously been never diagnosed with kidney diseases. Demographic data were collected by a structured questionnaire. Urinary protein was tested by dipstick method, and serum creatinine was measured by an auto-analyzer. Estimated glomerular filtration rate (eGFR) was calculated by using standard formula. CKD was diagnosed and classified according to the National Kidney Foundation (NKF) Kidney Disease Outcomes Quality Initiative (K/DOQI) guidelines. Results: A total of 18.2% respondents were found to have likely CKD to whom 82% were in stage 1 and 18% were in stage 2. The majority of the likely CKD respondents (30.1%) were in age >60 years. The prevalence of proteinuria was significantly (P=0.0001) higher among previously documented CKD patients compared to the control group. Logistic analysis revealed that after adjustments, CKD showed a significant association with diabetes mellitus (ORs: 7.46, P=0.00), smoking (ORs: 2.36, P=0.02), obesity (ORs: 3.98, P=0.00) and hypertension (ORs: 1.16, P=0.66) compared to control. Conclusion: A substantial number of adults were found to be unaware of the existence of CKD hence, large-scale prevention programs should be undertaken to reduce the classical risk factors of these disorders.


2019 ◽  
Vol 8 ◽  
pp. e935
Author(s):  
Marzieh Bakhshayeshkaram ◽  
Jamshid Roozbeh ◽  
Sayed Taghi Heydari ◽  
Behnam Honarvar ◽  
Mohammad Hossein Dabbaghmanesh ◽  
...  

Background: Currently we face a significant increase in the new cases of end-stage renal disease in developing countries. Hence it seems vital to work on strategies and reduce its development and progression. Determining the related risk factors can provide insight into achieving these policy-making goals. Therefore, this study was conducted in order to identify risk factors associated with chronic kidney disease in Iranian adult population. Material and Methods: This cross-sectional study was performed in Shiraz, through a random cluster sampling in 819 including 340 male and 479 female adult participants. Body mass indexes, waist circumference, blood pressure and biochemical profile were assessed. We evaluated the prevalence of CKD according to glomerular filtration rate (GFR) as well as possible risk factors. GFR was calculated based on “Chronic Kidney Disease Epidemiology Collaboration” creatinine equation. Result:  Mean age of our participants were 43.0± 14.0 years, and 58.5% were female. Our results showed 16.6% of patients with GFR less than 60 mL/min per 1.73. The proportion of participants having hypertension, obesity, high waist circumference, diabetes mellitus and history of cardiovascular disease were 17.3%,19.3%, 35%,9.4% and 5.3 %, respectively. Multiple regression analysis indicated an independent correlation between age, sex, dyslipidemia, and hypertension with CKD. Conclusion: This study indicates that CKD is a substantial health burden in Iranian adult population. Additionally, the results of this study addressed the importance of integrated strategies that aimed to identify, prevent, and treat non-communicable diseases fueling the development of CKD. [GMJ. 2019;8:e935]


2019 ◽  
Vol 8 ◽  
pp. 935 ◽  
Author(s):  
Marzieh Bakhshayeshkaram ◽  
Jamshid Roozbeh ◽  
Sayed Taghi Heydari ◽  
Behnam Honarvar ◽  
Mohammad Hossein Dabbaghmanesh ◽  
...  

Background: Currently we face a significant increase in the new cases of end-stage renal disease in developing countries. Hence it seems vital to work on strategies and reduce its development and progression. Determining the related risk factors can provide insight into achieving these policy-making goals. Therefore, this study was conducted in order to identify risk factors associated with chronic kidney disease in Iranian adult population. Material and Methods: This cross-sectional study was performed in Shiraz, through a random cluster sampling in 819 including 340 male and 479 female adult participants. Body mass indexes, waist circumference, blood pressure and biochemical profile were assessed. We evaluated the prevalence of CKD according to glomerular filtration rate (GFR) as well as possible risk factors. GFR was calculated based on “Chronic Kidney Disease Epidemiology Collaboration” creatinine equation. Results:  Mean age of our participants were 43.0± 14.0 years, and 58.5% were female. Our results showed 16.6% of patients with GFR less than 60 mL/min per 1.73. The proportion of participants having hypertension, obesity, high waist circumference, diabetes mellitus and history of cardiovascular disease were 17.3%,19.3%, 35%,9.4% and 5.3 %, respectively. Multiple regression analysis indicated an independent correlation between age, sex, dyslipidemia, and hypertension with CKD. Conclusion: This study indicates that CKD is a substantial health burden in Iranian adult population. Additionally, the results of this study addressed the importance of integrated strategies that aimed to identify, prevent, and treat non-communicable diseases fueling the development of CKD. [GMJ. 2019;8:e935]


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wichai Aekplakorn ◽  
Suwat Chariyalertsak ◽  
Pattapong Kessomboon ◽  
Sawitri Assanangkornchai ◽  
Surasak Taneepanichskul ◽  
...  

AbstractThere are limited data on chronic kidney disease of unknown etiology (CKDu) from Southeast Asia. Initially described in working age men, a common approach to detect CKDu that includes all adults has recently been proposed. We determined the prevalence, and risk factors for CKDu using data from a cross-sectional, nationally representative survey of the adult population of Thailand. We used a proxy for CKDu as age < 70 with impaired kidney function (eGFR < 60) in the absence of diabetes and hypertension (CKDu1) and heavy proteinuria (CKDu2). Prevalence estimates were probability-weighted for the Thai population. The associations between risk factors and CKDu or elderly subjects with eGFR < 60 without traditional causes were assessed by multivariable logistic regression. Of 17,329 subjects, the prevalence were: eGFR < 60, 5.3%; CKDu1 0.78%; CKDu2, 0.75%. CKDu differed by 4.3-folds between regions. Women, farmers/laborers, older age, gout, painkillers, rural area, and stones were independent risk factors for CKDu. Women, age, rural, gout, painkillers were significant risk factors for both CKDu and elderly subjects. These data collected using standardized methodology showed that the prevalence of CKDu in Thailand was low overall, although some regions had higher risk. Unlike other countries, Thai women had a two-fold higher risk of CKDu.


2015 ◽  
Vol 34 (5) ◽  
pp. 874-880 ◽  
Author(s):  
Chih-I. Ho ◽  
Jau-Yuan Chen ◽  
Shou-Yen Chen ◽  
Yi-Wen Tsai ◽  
Yi-Ming Weng ◽  
...  

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