scholarly journals Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples

2015 ◽  
Vol 43 (19) ◽  
pp. 9327-9339 ◽  
Author(s):  
Sudheer Kumar Gara ◽  
Yonghong Wang ◽  
Dhaval Patel ◽  
Yi Liu-Chittenden ◽  
Meenu Jain ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Tissue Samples ◽  
Genomic Changes ◽  
Genome Wide Analysis ◽  
Genome Wide

scholarly journals Genome-wide analysis of enhancer RNA in gene regulation across 12 mouse tissues

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Jen-Hao Cheng ◽  
David Zhi-Chao Pan ◽  
Zing Tsung-Yeh Tsai ◽  
Huai-Kuang Tsai
Keyword(s):  
Gene Regulation ◽  
Genome Wide Analysis ◽  
Enhancer Rna ◽  
Genome Wide ◽  
Mouse Tissues

scholarly journals Genome-Wide Analysis Reveals Human-Mediated Introgression from Western Pigs to Indigenous Chinese Breeds

Genes ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 275
Author(s):  
Jue Wang ◽  
Chengkun Liu ◽  
Jie Chen ◽  
Ying Bai ◽  
Kejun Wang ◽  
...  
Keyword(s):  
Growth Rate ◽  
Snp Array ◽  
Glucose Absorption ◽  
Related Gene ◽  
Feed Conversion ◽  
Genomic Changes ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Show Evidence ◽  
Genomic Regions

Genetic variations introduced via introgression from Western to Chinese pigs have contributed to the performance of Chinese breeds in traits such as growth rate and feed conversion efficiency. However, little is known about the underlying genomic changes that occurred during introgression and the types of traits affected by introgression. To address these questions, 525 animals were characterized using an SNP array to detect genomic regions that had been introgressed from European to indigenous Chinese breeds. The functions of genes located in introgressed regions were also investigated. Our data show that five out of six indigenous Chinese breeds show evidence of introgression from Western pigs, and eight introgressed genome regions are shared by five of the Chinese breeds. A region located on chr13: 12.8–13.1 M was affected by both introgression and artificial selection, and this region contains the glucose absorption related gene, OXSM, and the sensory related gene, NGLY. The results provide a foundation for understanding introgression from Western to indigenous Chinese pigs.

scholarly journals Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Petr P. Laktionov ◽  
Daniil A. Maksimov ◽  
Stanislav E. Romanov ◽  
Polina A. Antoshina ◽  
Olga V. Posukh ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Regulation Mechanisms
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