scholarly journals Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1

2015 ◽  
Vol 43 (11) ◽  
pp. 5297-5306 ◽  
Author(s):  
J. Malina ◽  
P. Scott ◽  
V. Brabec
Keyword(s):  
Selective Recognition ◽  
Ap Endonuclease ◽  
Abasic Sites ◽  
Shape Selective ◽  
Ap Endonuclease 1

Efficient inhibition of human AP endonuclease 1 (APE1) via substrate masking by abasic site-binding macrocyclic ligands

2015 ◽  
Vol 51 (88) ◽  
pp. 15948-15951 ◽  
Author(s):  
Naoko Kotera ◽  
Florent Poyer ◽  
Anton Granzhan ◽  
Marie-Paule Teulade-Fichou
Keyword(s):  
Macrocyclic Ligands ◽  
Abasic Site ◽  
Ap Endonuclease ◽  
Abasic Sites ◽  
Ap Endonuclease 1 ◽  
Site Binding

Bis-naphthalene macrocycles bind to abasic sites in DNA, leading to efficient inhibition of their cleavage by human AP endonuclease 1 (APE1).

Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents

DNA Repair ◽  
2012 ◽  
Vol 11 (1) ◽  
pp. 53-64 ◽  
Author(s):  
Karen S. Charret ◽  
Cristina E. Requena ◽  
Víctor M. Castillo-Acosta ◽  
Luis M. Ruiz-Pérez ◽  
Dolores González-Pacanowska ◽  
...  
Keyword(s):  
Trypanosoma Brucei ◽  
Ap Endonuclease ◽  
Abasic Sites ◽  
Dna Damaging Agents ◽  
Ap Endonuclease 1

scholarly journals A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β

2010 ◽  
Vol 39 (8) ◽  
pp. 3156-3165 ◽  
Author(s):  
De-Sheng Pei ◽  
Xiao-Jie Yang ◽  
Wei Liu ◽  
Jeroen E. J. Guikema ◽  
Carol E. Schrader ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Ap Endonuclease ◽  
Regulatory Circuit ◽  
Ap Endonuclease 1 ◽  
Base Excision

Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells

2004 ◽  
Vol 127 (3) ◽  
pp. 845-858 ◽  
Author(s):  
Song-Ze Ding ◽  
Ann M. O’Hara ◽  
Tim L. Denning ◽  
Bernadette Dirden-Kramer ◽  
Randy C. Mifflin ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Epithelial Cells ◽  
Gastric Epithelial Cells ◽  
Ap Endonuclease ◽  
Ap Endonuclease 1

AP endonuclease 1 as a key enzyme in repair of apurinic/apyrimidinic sites

2016 ◽  
Vol 81 (9) ◽  
pp. 951-967 ◽  
Author(s):  
N. S. Dyrkheeva ◽  
N. A. Lebedeva ◽  
O. I. Lavrik
Keyword(s):  
Ap Endonuclease ◽  
Key Enzyme ◽  
Ap Endonuclease 1

Schizosaccharomyces pombe encodes a mutated AP endonuclease 1

DNA Repair ◽  
2011 ◽  
Vol 10 (3) ◽  
pp. 296-305 ◽  
Author(s):  
Jon K. Laerdahl ◽  
Hanne Korvald ◽  
Line Nilsen ◽  
Kristin Dahl-Michelsen ◽  
Torbjørn Rognes ◽  
...  
Keyword(s):  
Schizosaccharomyces Pombe ◽  
Ap Endonuclease ◽  
Ap Endonuclease 1

Erratum to “Novel role of tyrosine in catalysis by human AP endonuclease 1” [DNA Repair 3 (2004) 1447–1455]

DNA Repair ◽  
2005 ◽  
Vol 4 (4) ◽  
pp. 521-522
Author(s):  
Sophia T. Mundle ◽  
Michael H. Fattal ◽  
Luisa F. Melo ◽  
Jean D. Coriolan ◽  
N. Edel O’Regan ◽  
...  
Keyword(s):  
Dna Repair ◽  
Ap Endonuclease ◽  
Ap Endonuclease 1

scholarly journals Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis

1998 ◽  
Vol 77 (7) ◽  
pp. 1169-1173 ◽  
Author(s):  
S Kakolyris ◽  
L Kaklamanis ◽  
K Engels ◽  
SB Fox ◽  
M Taylor ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Protein Expression ◽  
Lymph Node Status ◽  
Ap Endonuclease ◽  
Node Status ◽  
Ap Endonuclease 1
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