scholarly journals Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding

2008 ◽  
Vol 37 (2) ◽  
pp. 611-621 ◽  
Author(s):  
Özgül Persil Çetinkol ◽  
Nicholas V. Hud
Keyword(s):  
Molecular Recognition ◽  
Selective Binding ◽  
Alternative Method ◽  
Shape Selective ◽  
Small Ligands

Shape-Selective Binding of Geometrically-Constrainedbis-Distamycins to a DNA Duplex and a Model Okazaki Fragment of Identical Sequence

2000 ◽  
Vol 19 (8) ◽  
pp. 1365-1379 ◽  
Author(s):  
William H. Gmeiner ◽  
Wei Cui ◽  
Sanjay Sharma ◽  
Ana Maria Soto ◽  
Luis A. Marky ◽  
...  
Keyword(s):  
Dna Duplex ◽  
Selective Binding ◽  
Okazaki Fragment ◽  
Shape Selective

Molecular Recognition of Proteins: Sequence-Selective Binding of Aspartate Pairs in Helical Peptides

1995 ◽  
Vol 117 (3) ◽  
pp. 1143-1144 ◽  
Author(s):  
Jeffrey S. Albert ◽  
M. Scott Goodman ◽  
Andrew D. Hamilton
Keyword(s):  
Molecular Recognition ◽  
Helical Peptides ◽  
Selective Binding

Shape-selective binding of nitriles to the inorganic cavitand, V12O324−

1991 ◽  
Vol 29 (1-4) ◽  
pp. 97-104 ◽  
Author(s):  
W.G. Klemperer ◽  
T.A. Marquart ◽  
O.M. Yaghi
Keyword(s):  
Selective Binding ◽  
Shape Selective

Molecular recognition of carboxylates in the protein leucine zipper by a multivalent supramolecular ligand: residue-specific, sensitive and label-free probing by UV resonance Raman spectroscopy

2018 ◽  
Vol 20 (3) ◽  
pp. 1817-1820 ◽  
Author(s):  
B. Zakeri ◽  
S. Niebling ◽  
A. G. Martinéz ◽  
P. Sokkar ◽  
E. Sanchez-Garcia ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Molecular Recognition ◽  
Leucine Zipper ◽  
Resonance Raman Spectroscopy ◽  
Proof Of Concept ◽  
Label Free ◽  
Selective Binding ◽  
Concept Study ◽  
Uv Resonance Raman ◽  
Uv Resonance Raman Spectroscopy

Proof of concept study for using UVRR spectroscopy to monitor the selective binding of an artificial ligand to carboxylate residues of a protein.

No, Not That Way, the Other Way: Creating Active Sites in Self-Assembled Host Molecules

Synlett ◽  
2020 ◽  
Vol 31 (15) ◽  
pp. 1448-1463
Author(s):  
Richard J. Hooley
Keyword(s):  
Molecular Recognition ◽  
Self Assembly ◽  
Active Sites ◽  
Lessons Learned ◽  
Future Research ◽  
Binding Studies ◽  
Stereochemical Control ◽  
Shape Selective ◽  
Self Assembled ◽  
Catalyzed Reactions

This Account describes our efforts over the last decade to synthesize self-assembled metal–ligand cage complexes that display reactive functional groups on their interiors. This journey has taken us down a variety of research avenues, including studying the mechanism of reversible self-assembly, analyzing ligand self-sorting properties, post-assembly reactivity, molecular recognition, and binding studies, and finally reactivity and catalysis. Each of these individual topics are discussed here, as are the lessons learned along the way and the future research outlook. These self-assembled hosts are the closest mimics of enzymes to date, as they are capable of size- and shape-selective molecular recognition, substrate activation and turnover, as well as showing less common ‘biomimetic’ properties such as the ability to employ cofactors in reactivity, and alter the prevailing mechanism of the catalyzed reactions.1 Introduction2 Paddlewheels and Self-Sorting Behavior3 First-Row Transition-Metal-Mediated Assembly: Sorting and Stereochemical Control4 Post-Assembly Reactivity5 Molecular Recognition and Catalysis6 Conclusions and Outlook

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