scholarly journals The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes

2007 ◽  
Vol 36 (Database) ◽  
pp. D768-D772 ◽  
Author(s):  
J. Sprague ◽  
L. Bayraktaroglu ◽  
Y. Bradford ◽  
T. Conlin ◽  
N. Dunn ◽  
...  
Keyword(s):  
Model Organism ◽  
Information Network ◽  
Model Organism Database ◽  
Zebrafish Model

scholarly journals ZFIN, The zebrafish model organism database: Updates and new directions

genesis ◽  
2015 ◽  
Vol 53 (8) ◽  
pp. 498-509 ◽  
Author(s):  
Leyla Ruzicka ◽  
Yvonne M. Bradford ◽  
Ken Frazer ◽  
Douglas G. Howe ◽  
Holly Paddock ◽  
...  
Keyword(s):  
Model Organism ◽  
Model Organism Database ◽  
Zebrafish Model ◽  
Database Updates ◽  
New Directions

scholarly journals ZFIN, the Zebrafish Model Organism Database: increased support for mutants and transgenics

2012 ◽  
Vol 41 (D1) ◽  
pp. D854-D860 ◽  
Author(s):  
Douglas G. Howe ◽  
Yvonne M. Bradford ◽  
Tom Conlin ◽  
Anne E. Eagle ◽  
David Fashena ◽  
...  
Keyword(s):  
Model Organism ◽  
Model Organism Database ◽  
Zebrafish Model

scholarly journals The Zebrafish Model Organism Database: new support for human disease models, mutation details, gene expression phenotypes and searching

2016 ◽  
Vol 45 (D1) ◽  
pp. D758-D768 ◽  
Author(s):  
Douglas G. Howe ◽  
Yvonne M. Bradford ◽  
Anne Eagle ◽  
David Fashena ◽  
Ken Frazer ◽  
...  
Keyword(s):  
Gene Expression ◽  
Human Disease ◽  
Model Organism ◽  
Disease Models ◽  
Model Organism Database ◽  
Zebrafish Model

scholarly journals ZFIN: enhancements and updates to the zebrafish model organism database

2010 ◽  
Vol 39 (Database) ◽  
pp. D822-D829 ◽  
Author(s):  
Y. Bradford ◽  
T. Conlin ◽  
N. Dunn ◽  
D. Fashena ◽  
K. Frazer ◽  
...  
Keyword(s):  
Model Organism ◽  
Model Organism Database ◽  
Zebrafish Model

scholarly journals MaizeGDB update: new tools, data and interface for the maize model organism database

2015 ◽  
Vol 44 (D1) ◽  
pp. D1195-D1201 ◽  
Author(s):  
Carson M. Andorf ◽  
Ethalinda K. Cannon ◽  
John L. Portwood ◽  
Jack M. Gardiner ◽  
Lisa C. Harper ◽  
...  
Keyword(s):  
Model Organism ◽  
Model Organism Database

scholarly journals In Vitro and in Vivo Imaging of Nitroxyl with Copper Fluorescent Probe in Living Cells and Zebrafish

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2551 ◽  
Author(s):  
Sathyadevi Palanisamy ◽  
Yu-Liang Wang ◽  
Yu-Jen Chen ◽  
Chiao-Yun Chen ◽  
Fu-Te Tsai ◽  
...  
Keyword(s):  
Critical Role ◽  
Model Organism ◽  
Living Cells ◽  
Biological Species ◽  
Zebrafish Model ◽  
Physiological Processes ◽  
Collective Data ◽  
Angeli's Salt

Nitroxyl (HNO) plays a critical role in many physiological processes which includes vasorelaxation in heart failure, neuroregulation, and myocardial contractility. Powerful imaging tools are required to obtain information for understanding the mechanisms involved in these in vivo processes. In order to develop a rapid and high sensitive probe for HNO detection in living cells and the zebrafish model organism, 2-((2-(benzothiazole-2yl)benzylidene) amino)benzoic acid (AbTCA) as a ligand, and its corresponding copper(II) complex Cu(II)-AbTCA were synthesized. The reaction results of Cu(II)-AbTCA with Angeli’s salt showed that Cu(II)-AbTCA could detect HNO quantitatively in a range of 40–360 µM with a detection limit of 9.05 µM. Furthermore, Cu(II)-AbTCA is more selective towards HNO over other biological species including thiols, reactive nitrogen, and reactive oxygen species. Importantly, Cu(II)-AbTCA was successfully applied to detect HNO in living cells and zebrafish. The collective data reveals that Cu(II)-AbTCA could be used as a potential probe for HNO detection in living systems.

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