scholarly journals Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53

2007 ◽  
Vol 35 (6) ◽  
pp. 2093-2104 ◽  
Author(s):  
F. Vikhanskaya ◽  
M. K. Lee ◽  
M. Mazzoletti ◽  
M. Broggini ◽  
K. Sabapathy
Keyword(s):  
Gene Expression ◽  
Target Gene ◽  
Mutant P53 ◽  
Potential Mechanism ◽  
Gain Of Function ◽  
Target Gene Expression ◽  
P53 Target Gene ◽  
Expression Potential

MP60-14 THE VON HIPPEL LINDAU (VHL) TUMOR SUPPRESSOR INHIBITS P53 TARGET GENE EXPRESSION TO PROMOTE APOPTOSIS-RESISTANCE IN CANCER

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Adam Kinnaird ◽  
Peter Dromparis ◽  
Aristeidis Boukouris ◽  
Vikram Gurtu ◽  
Bruno Saleme ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Target Gene ◽  
Apoptosis Resistance ◽  
Von Hippel Lindau ◽  
Target Gene Expression ◽  
P53 Target Gene

scholarly journals Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression

Oncogene ◽  
2010 ◽  
Vol 29 (21) ◽  
pp. 3153-3162 ◽  
Author(s):  
P Li ◽  
D Wang ◽  
H Yao ◽  
P Doret ◽  
G Hao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Target Gene ◽  
Target Gene Expression ◽  
P53 Target Gene

2049-P: The Chd4 Helicase of the Nucleosome Remodeling and Deacetylase Complex Modulates Pdx1 Target Gene Expression In Vitro

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2049-P
Author(s):  
REBECCA K. DAVIDSON ◽  
NOLAN CASEY ◽  
JASON SPAETH
Keyword(s):  
Gene Expression ◽  
Target Gene ◽  
Nucleosome Remodeling ◽  
Target Gene Expression

scholarly journals On the way toward regulatable expression systems in acetic acid bacteria: target gene expression and use cases

2021 ◽  
Author(s):  
Philipp Moritz Fricke ◽  
Angelika Klemm ◽  
Michael Bott ◽  
Tino Polen
Keyword(s):  
Gene Expression ◽  
Acetic Acid ◽  
Literature Search ◽  
Target Gene ◽  
Target Genes ◽  
Recombinant Dna ◽  
Acetic Acid Bacteria ◽  
Homoserine Lactone ◽  
Expression Systems ◽  
Target Gene Expression

Abstract Acetic acid bacteria (AAB) are valuable biocatalysts for which there is growing interest in understanding their basics including physiology and biochemistry. This is accompanied by growing demands for metabolic engineering of AAB to take advantage of their properties and to improve their biomanufacturing efficiencies. Controlled expression of target genes is key to fundamental and applied microbiological research. In order to get an overview of expression systems and their applications in AAB, we carried out a comprehensive literature search using the Web of Science Core Collection database. The Acetobacteraceae family currently comprises 49 genera. We found overall 6097 publications related to one or more AAB genera since 1973, when the first successful recombinant DNA experiments in Escherichia coli have been published. The use of plasmids in AAB began in 1985 and till today was reported for only nine out of the 49 AAB genera currently described. We found at least five major expression plasmid lineages and a multitude of further expression plasmids, almost all enabling only constitutive target gene expression. Only recently, two regulatable expression systems became available for AAB, an N-acyl homoserine lactone (AHL)-inducible system for Komagataeibacter rhaeticus and an l-arabinose-inducible system for Gluconobacter oxydans. Thus, after 35 years of constitutive target gene expression in AAB, we now have the first regulatable expression systems for AAB in hand and further regulatable expression systems for AAB can be expected. Key points • Literature search revealed developments and usage of expression systems in AAB. • Only recently 2 regulatable plasmid systems became available for only 2 AAB genera. • Further regulatable expression systems for AAB are in sight.

Inhibition of prostate cancer growth by vitamin D: Regulation of target gene expression

2002 ◽  
Vol 88 (2) ◽  
pp. 363-371 ◽  
Author(s):  
Aruna V. Krishnan ◽  
Donna M. Peehl ◽  
David Feldman
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Vitamin D ◽  
Target Gene ◽  
Cancer Growth ◽  
Target Gene Expression
Sign in / Sign up

Export Citation Format

Share Document