scholarly journals Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56 419 completely sequenced and manually annotated full-length cDNAs

2006 ◽  
Vol 34 (14) ◽  
pp. 3917-3928 ◽  
Author(s):  
Jun-ichi Takeda ◽  
Yutaka Suzuki ◽  
Mitsuteru Nakao ◽  
Roberto A. Barrero ◽  
Kanako O. Koyanagi ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Large Scale ◽  
Human Gene ◽  
Full Length ◽  
Splicing Variants ◽  
Gene Transcripts ◽  
Identification And Characterization

scholarly journals Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Peanut

Genes ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 536 ◽  
Author(s):  
Xiaobo Zhao ◽  
Liming Gan ◽  
Caixia Yan ◽  
Chunjuan Li ◽  
Quanxi Sun ◽  
...  
Keyword(s):  
Large Scale ◽  
Target Genes ◽  
Sequencing Data ◽  
Regulatory Processes ◽  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization ◽  
Lower Expression ◽  
Weighted Correlation

Long non-coding RNAs (lncRNAs) are involved in various regulatory processes although they do not encode protein. Presently, there is little information regarding the identification of lncRNAs in peanut (Arachis hypogaea Linn.). In this study, 50,873 lncRNAs of peanut were identified from large-scale published RNA sequencing data that belonged to 124 samples involving 15 different tissues. The average lengths of lncRNA and mRNA were 4335 bp and 954 bp, respectively. Compared to the mRNAs, the lncRNAs were shorter, with fewer exons and lower expression levels. The 4713 co-expression lncRNAs (expressed in all samples) were used to construct co-expression networks by using the weighted correlation network analysis (WGCNA). LncRNAs correlating with the growth and development of different peanut tissues were obtained, and target genes for 386 hub lncRNAs of all lncRNAs co-expressions were predicted. Taken together, these findings can provide a comprehensive identification of lncRNAs in peanut.

Large-scale identification and characterization of phenolic compounds and their marker–trait association in wheat

Euphytica ◽  
2020 ◽  
Vol 216 (8) ◽  
Author(s):  
Monica Sharma ◽  
Mohammed Saba Rahim ◽  
Pankaj Kumar ◽  
Ankita Mishra ◽  
Himanshu Sharma ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Large Scale ◽  
Trait Association ◽  
Identification And Characterization

scholarly journals Identification and Characterization of the Murine and Human Gene Encoding the Tuberoinfundibular Peptide of 39 Residues

Endocrinology ◽  
2002 ◽  
Vol 143 (3) ◽  
pp. 1047-1057 ◽  
Author(s):  
Markus R. John ◽  
Maya Arai ◽  
David A. Rubin ◽  
Kenneth B. Jonsson ◽  
Harald Jüppner
Keyword(s):  
Human Gene ◽  
Gene Encoding ◽  
Tuberoinfundibular Peptide ◽  
Identification And Characterization

Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28

Gene ◽  
2003 ◽  
Vol 314 ◽  
pp. 113-120 ◽  
Author(s):  
G. Vazza ◽  
S. Picelli ◽  
A. Bozzato ◽  
M.L. Mostacciuolo
Keyword(s):  
Gene Mapping ◽  
Human Gene ◽  
Human Gene Mapping ◽  
Identification And Characterization

Cloning and characterization of an alternative splicing transcript of the gene coding for human cytidine deaminase

2007 ◽  
Vol 85 (1) ◽  
pp. 96-102 ◽  
Author(s):  
Bianca Cristina Garcia Lisboa ◽  
Tamara da Rocha Machado ◽  
Daniel Carvalho Pimenta ◽  
Sang Won Han
Keyword(s):  
Alternative Splicing ◽  
Dna Sequences ◽  
Genomic Sequence ◽  
Cytidine Deaminase ◽  
Alternative Form ◽  
Nih3t3 Cells ◽  
Reading Frame ◽  
Gene Coding ◽  
Identification And Characterization

Human cytidine deaminase (HCD) catalyzes the deamination of cytidine or deoxycytidine to uridine or deoxyuridine, respectively. The genomic sequence of HCD is formed by 31 kb with 4 exons and several alternative splicing signals, but an alternative form of HCD has yet to be reported. Here we describe the cloning and characterization of a small form of HCD, HSCD, and it is likely to be a product of alternative splicing of HCD. The alignment of DNA sequences shows that the HSCD matches HCD in 2 parts, except for a deletion of 170 bp. Based on the HCD genome organization, exons 1 and 4 should be joined and all sequences of introns and exons 2 and 3 should be deleted by splicing. This alternative splicing shifted the translation of the reading frame from the point of splicing. The estimated molecular mass is 9.8 kDa, and this value was confirmed by Western blot and mass spectroscopy after expressing the gene fused with glutathionine-S-transferase in the pGEX vector. The deletion and shift of the reading frame caused a loss of HCD activity, which was confirmed by enzyme assay and also with NIH3T3 cells modified to express HSCD and challenged against cytosine arabinoside. In this work we describe the identification and characterization of HSCD, which is the product of alternative splicing of the HCD gene.

Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1

1998 ◽  
Vol 82 (3-4) ◽  
pp. 147-152 ◽  
Author(s):  
M. Kimura ◽  
Y. Matsuda ◽  
T. Yoshioka ◽  
N. Sumi ◽  
Y. Okano
Keyword(s):  
Human Gene ◽  
Identification And Characterization

scholarly journals Identification and characterization of growing large-scale en-echelon fractures in a salt mine

2013 ◽  
Vol 196 (2) ◽  
pp. 1092-1105 ◽  
Author(s):  
Samira Maghsoudi ◽  
Sebastian Hainzl ◽  
Simone Cesca ◽  
Torsten Dahm ◽  
Diethelm Kaiser
Keyword(s):  
Large Scale ◽  
Salt Mine ◽  
Identification And Characterization
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