scholarly journals Nucleotide-dependent interactions between a fork junction-RNA polymerase complex and an AAA+ transcriptional activator protein

2004 ◽  
Vol 32 (15) ◽  
pp. 4596-4608 ◽  
Author(s):  
W. V. Cannon
Keyword(s):  
Rna Polymerase ◽  
Transcriptional Activator ◽  
Polymerase Complex ◽  
Activator Protein ◽  
Transcriptional Activator Protein

scholarly journals Location, structure, and function of the target of a transcriptional activator protein.

1994 ◽  
Vol 8 (24) ◽  
pp. 3058-3067 ◽  
Author(s):  
H Tang ◽  
K Severinov ◽  
A Goldfarb ◽  
D Fenyo ◽  
B Chait ◽  
...  
Keyword(s):  
Transcriptional Activator ◽  
Structure And Function ◽  
Activator Protein ◽  
Transcriptional Activator Protein ◽  
And Function

scholarly journals Proline-independent binding of PUT3 transcriptional activator protein detected by footprinting in vivo.

1991 ◽  
Vol 11 (1) ◽  
pp. 564-567 ◽  
Author(s):  
J D Axelrod ◽  
J Majors ◽  
M C Brandriss
Keyword(s):  
Gene Product ◽  
Transcriptional Activator ◽  
Activator Protein ◽  
Transcriptional Activator Protein ◽  
Proline Utilization ◽  
Genes Encoding ◽  
Utilization Pathway

The PUT3 gene product is a transcriptional activator required for expression of the enzymes of the proline utilization pathway. Using two methods of footprinting in vivo, we have determined that PUT3 protein is poised at the promoters of the genes encoding these enzymes and that proline-mediated induction modulates the activity of constitutively bound PUT3.

scholarly journals The Hypersensitive Response to Tomato leaf curl New Delhi virus Nuclear Shuttle Protein Is Inhibited by Transcriptional Activator Protein

2007 ◽  
Vol 20 (12) ◽  
pp. 1581-1588 ◽  
Author(s):  
Mazhar Hussain ◽  
Shahid Mansoor ◽  
Shazia Iram ◽  
Yusuf Zafar ◽  
Rob W. Briddon
Keyword(s):  
Cell Death ◽  
Hypersensitive Response ◽  
Transcriptional Activator ◽  
Tomato Leaf ◽  
New Delhi ◽  
Nuclear Shuttle Protein ◽  
Activator Protein ◽  
Transcriptional Activator Protein ◽  
Tomato Leaf Curl ◽  
Leaf Curl

The hypersensitive response (HR) is a common feature of plant disease resistance reactions and a type of programmed cell death (PCD). Many pathogens are able to modulate pathways involved in cell death. In contrast to animal viruses, inhibitors of PCD activity have not been identified for plant-infecting viruses. Previously, we have reported that the nuclear shuttle protein (NSP) of Tomato leaf curl New Delhi virus (ToLCNDV) induces an HR in Nicotiana tabacum and Lycopersicon esculentum plants when expressed under the control of the Cauliflower mosaic virus 35S promoter. However, HR is not evident in plants infected with ToLCNDV, suggesting that the virus encodes a factor (or factors) that counters this response. Analysis of all ToLCNDV-encoded genes pinpointed the transcriptional activator protein (TrAP) as the factor mediating the anti-HR effect. Deletion mutagenesis showed the central region of TrAP, containing a zinc finger domain and nuclear localization signal, to be important in inhibiting the HR. These results demonstrate that TrAP counters HR-induced cell death, the first such activity identified for a plant-infecting virus.

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