scholarly journals Holliday junction resolvase in Schizosaccharomyces pombe has identical endonuclease activity to the CCE1 homologue YDC2

1998 ◽  
Vol 26 (2) ◽  
pp. 594-601 ◽  
Author(s):  
M. Oram ◽  
A. Keeley ◽  
I. Tsaneva
2012 ◽  
Vol 151 (3) ◽  
pp. 317-327 ◽  
Author(s):  
Y. Yang ◽  
S. Ishino ◽  
T. Yamagami ◽  
T. Kumamaru ◽  
H. Satoh ◽  
...  

Genetics ◽  
1996 ◽  
Vol 144 (1) ◽  
pp. 27-41 ◽  
Author(s):  
Larry A Gilbertson ◽  
Franklin W Stahl

Abstract We tested predictions of the double-strand break repair (DSBR) model for meiotic recombination by examining the segregation patterns of small palindromic insertions, which frequently escape mismatch repair when in heteroduplex DNA. The palindromes flanked a well characterized DSB site at the ARC4 locus. The “canonical” DSBR model, in which only 5′ ends are degraded and resolution of the four-stranded intermediate is by Holliday junction resolvase, predicts that hDNA will frequently occur on both participating chromatids in a single event. Tetrads reflecting this configuration of hDNA were rare. In addition, a class of tetrads not predicted by the canonical DSBR model was identified. This class represented events that produced hDNA in a “trans” configuration, on opposite strands of the same duplex on the two sides of the DSB site. Whereas most classes of convertant tetrads had typical frequencies of associated crossovers, tetrads with trans hDNA were parental for flanking markers. Modified versions of the DSBR model, including one that uses a topoisomerase to resolve the canonical DSBR intermediate, are supported by these data.


Cell ◽  
2001 ◽  
Vol 107 (4) ◽  
pp. 537-548 ◽  
Author(s):  
Michael N. Boddy ◽  
Pierre-Henri L. Gaillard ◽  
W.Hayes McDonald ◽  
Paul Shanahan ◽  
John R. Yates ◽  
...  

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