scholarly journals Association of a truncated cytochromecprocessed pseudogene with a similarly truncated member from a long interspersed repeat family of rat

1985 ◽  
Vol 13 (3) ◽  
pp. 763-775 ◽  
Author(s):  
Richard C. Scarpulla
Keyword(s):  
Repeat Family

scholarly journals Definition of the Mycobacterial SOS Box and Use To Identify LexA-Regulated Genes in Mycobacterium tuberculosis

2002 ◽  
Vol 184 (12) ◽  
pp. 3287-3295 ◽  
Author(s):  
Elaine O. Davis ◽  
Edith M. Dullaghan ◽  
Lucinda Rand
Keyword(s):  
Dna Damage ◽  
Mycobacterium Tuberculosis ◽  
Dna Polymerase ◽  
Expression Data ◽  
Repeat Family ◽  
New Genes ◽  
Lexa Binding ◽  
Definition Of ◽  
Inducible Genes ◽  
Single Mismatch

ABSTRACT The bases of the mycobacterial SOS box important for LexA binding were determined by replacing each base with every other and examining the effect on the induction of a reporter gene following DNA damage. This analysis revealed that the SOS box was longer than originally thought by 2 bp in each half of the palindromic site. A search of the Mycobacterium tuberculosis genome sequence with the new consensus, TCGAAC(N)4GTTCGA, identified 4 sites which were perfect matches and 12 sites with a single mismatch which were predicted to bind LexA. Genes which could potentially be regulated by these SOS boxes were ascertained from their positions relative to the sites. Examination of expression data for these genes following DNA damage identified 12 new genes which are most likely regulated by LexA as well as the known M. tuberculosis DNA damage-inducible genes recA, lexA, and ruvC. Of these 12 genes, only 2 have a predicted function: dnaE2, a component of DNA polymerase III, and linB, which is similar to 1,3,4,6-tetrachloro-1,4-cylcohexadiene hydrolase. Curiously, of the remaining 10 genes predicted to be LexA regulated, 7 are members of the M. tuberculosis 13E12 repeat family, which has some of the characteristics of mobile elements.

A Centromeric Tandem Repeat Family Originating From a Part of Ty3/gypsy-Retroelement in Wheat and Its Relatives

Genetics ◽  
2003 ◽  
Vol 164 (2) ◽  
pp. 665-672 ◽  
Author(s):  
Zhi-Jun Cheng ◽  
Minoru Murata
Keyword(s):  
In Situ Hybridization ◽  
Tandem Repeats ◽  
Diploid Species ◽  
Upstream Region ◽  
Aegilops Speltoides ◽  
Repeat Family ◽  
B Genome ◽  
Intervening Sequences ◽  
Wild Diploid Species

AbstractFrom a wild diploid species that is a relative of wheat, Aegilops speltoides, a 301-bp repeat containing 16 copies of a CAA microsatellite was isolated. Southern blot and fluorescence in situ hybridization revealed that ∼250 bp of the sequence is tandemly arrayed at the centromere regions of A- and B-genome chromosomes of common wheat and rye chromosomes. Although the DNA sequence of this 250-bp repeat showed no notable homology in the databases, the flanking or intervening sequences between the repeats showed high homologies (>82%) to two separate sequences of the gag gene and its upstream region in cereba, a Ty3/gypsy-like retroelement of Hordeum vulgare. Since the amino acid sequence deduced from the 250 bp with seven CAAs showed some similarity (∼53%) to that of the gag gene, we concluded that the 250-bp repeats had also originated from the cereba-like retroelements in diploid wheat such as Ae. speltoides and had formed tandem arrays, whereas the 300-bp repeats were dispersed as a part of cereba-like retroelements. This suggests that some tandem repeats localized at the centromeric regions of cereals and other plant species originated from parts of retrotransposons.

Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome

1985 ◽  
Vol 182 (4) ◽  
pp. 477-485 ◽  
Author(s):  
J. Wolfe ◽  
S.M. Darling ◽  
R.P. Erickson ◽  
I.W. Craig ◽  
V.J. Buckle ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Repeat Family ◽  
Centromeric Repeat ◽  
Isolation And Characterization ◽  
Human Y Chromosome

Analysis of the organisation and localisation of the FSHD-associated tandem array in primates: Implications for the origin and evolution of the 3.3 kb repeat family

Chromosoma ◽  
1996 ◽  
Vol 105 (3) ◽  
pp. 180-189 ◽  
Author(s):  
Lorraine N. Clark ◽  
Udo Koehler ◽  
David C. Ward ◽  
Johannes Wienberg ◽  
Jane E. Hewitt
Keyword(s):  
Tandem Array ◽  
Repeat Family ◽  
Origin And Evolution

Molecular characterization and distribution of a 145-bp tandem repeat family in the genus Populus

Genome ◽  
1999 ◽  
Vol 42 (5) ◽  
pp. 909-918 ◽  
Author(s):  
J. Rajagopal ◽  
S. Das ◽  
D.K. Khurana ◽  
P.S. Srivastava ◽  
M. Lakshmikumaran
Keyword(s):  
Molecular Characterization ◽  
Tandem Repeat ◽  
Repeat Family

The pericentromeric heterochromatin of the grass Zingeria biebersteiniana (2n = 4) is composed of Zbcen1-type tandem repeats that are intermingled with accumulated dispersedly organized sequences

Genome ◽  
2001 ◽  
Vol 44 (6) ◽  
pp. 955-961 ◽  
Author(s):  
Verity A Saunders ◽  
Andreas Houben
Keyword(s):  
In Situ Hybridization ◽  
Tandem Repeat ◽  
Tandem Repeats ◽  
Repetitive Sequences ◽  
Pericentromeric Region ◽  
Pericentromeric Heterochromatin ◽  
Repeat Family ◽  
Dna Reassociation ◽  
Copy Dna

DNA reassociation and hydroxyapatite chromatography were used to isolate high-copy DNA of the grass Zingeria biebersteiniana (2n = 4). In situ hybridization demonstrated that the DNA isolated was enriched for pericentromere-specific repetitive sequences. One abundant pericentromere-specific component is the differentially methylated tandem-repeat family Zbcen1. Other sequences isolated, Zb46 and Zb47A, are dispersed and display similarity to parts of the gypsy- and copia-like retrotransposable elements of other grasses. In situ hybridization with the copia-like sequence Zb47A resulted in dispersed labelling along the chromosome arms, with a significant signal accumulation in the pericentromeric region of all chromosomes. It is concluded that the pericentromeric heterochromatin of Z. biebersteiniana is composed of members of the Zbcen1 tandem repeat family and that these tandem arrays are intermingled with accumulated putative copia-like retrotransposon sequences. An observed Rabl interphase orientation suggests that the length of the chromosomes rather than the genome size is the determining factor of the Rabl phenomenon.Key Words: centromere, heterochromatin, tandemly repeated DNA, retrotransposon-like, DNA reassociation.

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