scholarly journals Influence of TCDD and natural Ah receptor agonists on benzo[a]pyrene-DNA adduct formation in the Caco-2 human colon cell line

Mutagenesis ◽  
2007 ◽  
Vol 23 (1) ◽  
pp. 67-73 ◽  
Author(s):  
P. W. J. de Waard ◽  
T. M. C. M. de Kok ◽  
L. M. Maas ◽  
A. A. C. M. Peijnenburg ◽  
R. L. A. P. Hoogenboom ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Colon ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Ah Receptor ◽  
Receptor Agonists ◽  
Human Colon Cell Line ◽  
Colon Cell ◽  
Colon Cell Line

scholarly journals Determination of cell death induced by lovastatin on human colon cell line HT29 using comet assay

2011 ◽  
Vol 205 ◽  
pp. S116-S117
Author(s):  
M. Rezaei ◽  
H. Kalantari ◽  
M. HashemiTabar ◽  
M. Jafari ◽  
Z. Bahadori
Keyword(s):  
Cell Death ◽  
Comet Assay ◽  
Cell Line ◽  
Human Colon ◽  
Human Colon Cell Line ◽  
Colon Cell ◽  
Colon Cell Line

scholarly journals Arabinoxylan-Based Particles: In Vitro Antioxidant Capacity and Cytotoxicity on a Human Colon Cell Line

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 349 ◽  
Author(s):  
Mayra A. Mendez-Encinas ◽  
Elizabeth Carvajal-Millan ◽  
Agustín Rascón-Chu ◽  
Humberto Astiazarán-García ◽  
Dora E. Valencia-Rivera ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Cell Line ◽  
Human Colon ◽  
Colon Cells ◽  
Antioxidant Power ◽  
Human Colon Cell Line ◽  
Colon Cell ◽  
Colon Cell Line

Background and objectives: Arabinoxylans (AX) can gel and exhibit antioxidant capacity. Previous studies have demonstrated the potential application of AX microspheres as colon-targeted drug carriers. However, the cytotoxicity of AX gels has not been investigated so far. Therefore, the aim of the present study was to prepare AX-based particles (AXM) by coaxial electrospraying method and to investigate their antioxidant potential and cytotoxicity on human colon cells. Materials and Methods: The gelation of AX was studied by monitoring the storage (G′) and loss (G′′) moduli. The morphology of AXM was evaluated using optical and scanning electron microscopy (SEM). The in vitro antioxidant activity of AX before and after gelation was measured using the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods. In addition, the effect of AX and AXM on the proliferation of human colon cells (CCD 841 CoN) was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results: The final G′ and G′′ values for AX gels were 293 and 0.31 Pa, respectively. AXM presented spherical shape and rough surface with a three-dimensional and porous network. The swelling ratio and mesh size of AXM were 35 g water/g AX and 27 nm, respectively. Gelation decreased the antioxidant activity of AX by 61–64 %. AX and AXM did not affect proliferation or show any toxic effect on the normal human colon cell line CCD 841 CoN. Conclusion: The results indicate that AXM could be promising biocompatible materials with antioxidant activity.

scholarly journals Effect of Changweiqing on miR-30a/Beclin1 pathway in subcutaneous xenografts of human colon cell line HCT116/L-OHP in nude mice

2017 ◽  
Vol 25 (12) ◽  
pp. 1061
Author(s):  
Rui-Juan Zhang ◽  
Jian-Hua Xu ◽  
Jue Sun ◽  
Fang Liang ◽  
Yong Zhang ◽  
...  
Keyword(s):  
Cell Line ◽  
Nude Mice ◽  
Human Colon ◽  
Human Colon Cell Line ◽  
Colon Cell ◽  
Colon Cell Line

Effect of butyrate and fermentation products on epithelial integrity in a mucus-secreting human colon cell line

2018 ◽  
Vol 40 ◽  
pp. 9-17 ◽  
Author(s):  
Ditte Søvsø Gundelund Nielsen ◽  
Bent Borg Jensen ◽  
Peter Kappel Theil ◽  
Tina Skau Nielsen ◽  
Knud Erik Bach Knudsen ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Colon ◽  
Fermentation Products ◽  
Epithelial Integrity ◽  
Human Colon Cell Line ◽  
Colon Cell ◽  
Colon Cell Line
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