scholarly journals A Comprehensive, High-Resolution Map of a Gene’s Fitness Landscape

2016 ◽  
Vol 33 (5) ◽  
pp. 1378-1378 ◽  
Author(s):  
Elad Firnberg ◽  
Jason W. Labonte ◽  
Jeffrey J. Gray ◽  
Marc Ostermeier
Keyword(s):  
High Resolution ◽  
Fitness Landscape ◽  
High Resolution Map ◽  
Resolution Map

scholarly journals A Comprehensive, High-Resolution Map of a Gene’s Fitness Landscape

2014 ◽  
Vol 31 (6) ◽  
pp. 1581-1592 ◽  
Author(s):  
Elad Firnberg ◽  
Jason W. Labonte ◽  
Jeffrey J. Gray ◽  
Marc Ostermeier
Keyword(s):  
High Resolution ◽  
Fitness Landscape ◽  
High Resolution Map ◽  
Resolution Map

Tomato chromosome 6: a high resolution map of the long arm and construction of a composite integrated marker-order map

1996 ◽  
Vol 92 (8) ◽  
pp. 1065-1072 ◽  
Author(s):  
M. F. van Wordragen ◽  
R. L. Weide ◽  
E. Coppoolse ◽  
P. Zabel ◽  
M. Koornneef
Keyword(s):  
High Resolution ◽  
Marker Order ◽  
Chromosome 6 ◽  
Tomato Chromosome ◽  
High Resolution Map ◽  
Resolution Map

scholarly journals A high-resolution map of bacteriophage ϕX174 transcription

Virology ◽  
2020 ◽  
Vol 547 ◽  
pp. 47-56 ◽  
Author(s):  
Dominic Y. Logel ◽  
Paul R. Jaschke
Keyword(s):  
High Resolution ◽  
High Resolution Map ◽  
Resolution Map

A high-resolution map of the chromosomal region surrounding the nude gene

Genomics ◽  
1995 ◽  
Vol 26 (2) ◽  
pp. 308-317 ◽  
Author(s):  
C.C. Blackburn ◽  
J. Griffith ◽  
G. Morahan
Keyword(s):  
High Resolution ◽  
Chromosomal Region ◽  
High Resolution Map ◽  
Resolution Map

scholarly journals A New High-Resolution Map of World Mountains and an Online Tool for Visualizing and Comparing Characterizations of Global Mountain Distributions

2018 ◽  
Vol 38 (3) ◽  
pp. 240-249 ◽  
Author(s):  
Roger Sayre ◽  
Charlie Frye ◽  
Deniz Karagulle ◽  
Jürg Krauer ◽  
Sean Breyer ◽  
...  
Keyword(s):  
High Resolution ◽  
Online Tool ◽  
High Resolution Map ◽  
Resolution Map

scholarly journals The architecture of SARS-CoV-2 transcriptome

2020 ◽  
Author(s):  
Dongwan Kim ◽  
Joo-Yeon Lee ◽  
Jeong-Sun Yang ◽  
Jun Won Kim ◽  
V. Narry Kim ◽  
...  
Keyword(s):  
High Resolution ◽  
Rna Sequencing ◽  
Rna Modification ◽  
List Type ◽  
Rna Modifications ◽  
Subgenomic Rnas ◽  
Frequent Motif ◽  
High Resolution Map ◽  
Functional Investigation ◽  
Resolution Map

AbstractSARS-CoV-2 is a betacoronavirus that is responsible for the COVID-19 pandemic. The genome of SARS-CoV-2 was reported recently, but its transcriptomic architecture is unknown. Utilizing two complementary sequencing techniques, we here present a high-resolution map of the SARS-CoV-2 transcriptome and epitranscriptome. DNA nanoball sequencing shows that the transcriptome is highly complex owing to numerous recombination events, both canonical and noncanonical. In addition to the genomic RNA and subgenomic RNAs common in all coronaviruses, SARS-CoV-2 produces a large number of transcripts encoding unknown ORFs with fusion, deletion, and/or frameshift. Using nanopore direct RNA sequencing, we further find at least 41 RNA modification sites on viral transcripts, with the most frequent motif being AAGAA. Modified RNAs have shorter poly(A) tails than unmodified RNAs, suggesting a link between the internal modification and the 3′ tail. Functional investigation of the unknown ORFs and RNA modifications discovered in this study will open new directions to our understanding of the life cycle and pathogenicity of SARS-CoV-2.HighlightsWe provide a high-resolution map of SARS-CoV-2 transcriptome and epitranscriptome using nanopore direct RNA sequencing and DNA nanoball sequencing.The transcriptome is highly complex owing to numerous recombination events, both canonical and noncanonical.In addition to the genomic and subgenomic RNAs common in all coronaviruses, SARS-CoV-2 produces transcripts encoding unknown ORFs.We discover at least 41 potential RNA modification sites with an AAGAA motif.

scholarly journals Fragmentary structure in the L1551 molecular outflow

1991 ◽  
Vol 147 ◽  
pp. 480-481
Author(s):  
Nicholas D. Parker ◽  
Glenn J. White
Keyword(s):  
High Resolution ◽  
Thin Shell ◽  
Low Velocity ◽  
Fragmentary Structure ◽  
Molecular Outflow ◽  
High Resolution Map ◽  
Ambient Gas ◽  
Resolution Map

We have obtained a high resolution map of the 12CO J=3—2 emission in the vicinity of HH102 in the L1551 molecular outflow. The data reveal the presence of several bright clumps within the thin shell of low-velocity blue-shifted outflowing gas. There is evidence for further fragmentation in the clumps, as signified by the high derived excitation temperatures and low beam-filling factors. The region of peculiarly energetic activity associated with HH102 coincides with the projected location of impact of a radio jet from IRS5 with the dense ambient gas surrounding the outflow cavity.

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