scholarly journals Unmelanized Plumage Patterns in Old World Leaf Warblers Do Not Correspond to Sequence Variation at the Melanocortin-1 Receptor Locus (MC1R)

2003 ◽  
Vol 20 (10) ◽  
pp. 1675-1681 ◽  
Author(s):  
E. A. MacDougall-Shackleton
2016 ◽  
Vol 29 (4) ◽  
pp. 777-789 ◽  
Author(s):  
K. Supriya ◽  
M. Rowe ◽  
T. Laskemoen ◽  
D. Mohan ◽  
T. D. Price ◽  
...  

2014 ◽  
Vol 51 (3) ◽  
pp. 270-274 ◽  
Author(s):  
Jing Huang ◽  
Bing Zhou ◽  
Da-Qian He ◽  
Shi-Yi Chen ◽  
Qing Zhu ◽  
...  

Nature ◽  
1992 ◽  
Vol 355 (6363) ◽  
pp. 817-821 ◽  
Author(s):  
Adam D. Rich man ◽  
Trevor Price

Evolution ◽  
1997 ◽  
Vol 51 (2) ◽  
pp. 552-561 ◽  
Author(s):  
Trevor D. Price ◽  
Andreas J. Helbig ◽  
Adam D. Richman
Keyword(s):  

Evolution ◽  
1997 ◽  
Vol 51 (2) ◽  
pp. 552 ◽  
Author(s):  
Trevor D. Price ◽  
Andreas J. Helbig ◽  
Adam D. Richman
Keyword(s):  

Genetics ◽  
2001 ◽  
Vol 158 (3) ◽  
pp. 1253-1268 ◽  
Author(s):  
Kateryna D Makova ◽  
Michele Ramsay ◽  
Trefor Jenkins ◽  
Wen-Hsiung Li

AbstractAn ∼6.6-kb region located upstream from the melanocortin 1 receptor (MC1R) gene and containing its promoter was sequenced in 54 humans (18 Africans, 18 Asians, and 18 Europeans) and in one chimpanzee, gorilla, and orangutan. Seventy-six polymorphic sites were found among the human sequences and the average nucleotide diversity (π) was 0.141%, one of the highest among all studies of nuclear sequence variation in humans. Opposite to the pattern observed in the MC1R coding region, in the present region π is highest in Africans (0.136%) compared to Asians (0.116%) and Europeans (0.122%). The distributions of π, θ, and Fu and Li's F-statistic are nonuniform along the sequence and among continents. The pattern of genetic variation is consistent with a population expansion in Africans. We also suggest a possible phase of population size reduction in non-Africans and purifying selection acting in the middle subregion and parts of the 5′ subregion in Africans. We hypothesize diversifying selection acting on some sites in the 5′ and 3′ subregions or in the MC1R coding region in Asians and Europeans, though we cannot reject the possibility of relaxation of functional constraints in the MC1R gene in Asians and Europeans. The mutation rate in the sequenced region is 1.65 × 10—9 per site per year. The age of the most recent common ancestor for this region is similar to that for the other long noncoding regions studied to date, providing evidence for ancient gene genealogies. Our population screening and phylogenetic footprinting suggest potentially important sites for the MC1R promoter function.


2010 ◽  
Vol 365 (1547) ◽  
pp. 1749-1762 ◽  
Author(s):  
Trevor D. Price

Many continental sister species are allopatric or parapatric, ecologically similar and long separated, of the order of millions of years. Sympatric, ecologically differentiated, species, are often even older. This raises the question of whether build-up of sympatric diversity generally follows a slow process of divergence in allopatry, initially without much ecological change. I review patterns of speciation among birds belonging to the continental Eurasian Old World leaf warblers ( Phylloscopus and Seicercus ). I consider speciation to be a three-stage process (range expansions, barriers to gene flow, reproductive isolation) and ask how ecological factors at each stage have contributed to speciation, both among allopatric/parapatric sister species and among those lineages that eventually led to currently sympatric species. I suggest that time is probably the critical factor that leads to reproductive isolation between sympatric species and that a strong connection between ecological divergence and reproductive isolation remains to be established. Besides reproductive isolation, ecological factors can affect range expansions (e.g. habitat tracking) and the formation of barriers (e.g. treeless areas are effective barriers for warblers). Ecological factors may often limit speciation on continents because range expansions are difficult in ‘ecologically full’ environments.


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