scholarly journals Nicotianamine and histidine/proline are, respectively, the most important copper chelators in xylem sap of Brassica carinata under conditions of copper deficiency and excess

2008 ◽  
Vol 60 (1) ◽  
pp. 269-277 ◽  
Author(s):  
B. Irtelli ◽  
W. A. Petrucci ◽  
F. Navari-Izzo
Keyword(s):  
Copper Deficiency ◽  
Xylem Sap ◽  
Brassica Carinata ◽  
Copper Chelators

Aortic lesions in copper deficiency: Modification by dietary carbohydrates

1986 ◽  
Vol 44 ◽  
pp. 358-359
Author(s):  
U. Bielenberg
Keyword(s):  
Copper Deficiency ◽  
Male Rats ◽  
Dietary Carbohydrates ◽  
Dietary Copper ◽  
Serum Ceruloplasmin ◽  
Hepatic Copper ◽  
Dietary Treatments ◽  
Feeding Diets ◽  
Ceruloplasmin Activity ◽  
Simple Carbohydrate

Copper deficiency can cause cardiovascular lesions in experimental animals. Previous experiments have shown that the biochemical and itDrphologic lesions induced by deprivation of dietary copper can be suppressed by feeding diets containing starch or can be magnified by a high sucrose diet. In a recent study it was found that the more severe signs of copper deficiency in rats fed sucrose as compared to starch were due to the fructose moiety of sucrose. Although fructose as compared to starch markedly enhanced the symptoms of copper deficiency, the possibility that an effect of dietary carbohydrates due to the nature of the simple carbohydrate (fructose vs glucose) cannot be excluded. The present study was designed to determine if the severity of copper deficiency in rats fed sucrose as compared to starch is due to the glucose as well as the fructose moiety of sucrose. This portion of the study assessed the morphologic changes in aortas of seventy weanling male rats who were fed, for 9 weeks, copper deficient or copper supplemented diets containing either 62% starch, fructose or glucose. The starch-fed copper supplemented group served as the most normal controls. Rats were sacrificed after 9 weeks of dietary treatments. Copper deficiency was verified by reduced serum ceruloplasmin activity and serum and hepatic copper concentration.

Abstract #337: A Rare Case of Copper Deficiency and Celiac Disease

2006 ◽  
Vol 12 ◽  
pp. 96-97
Author(s):  
Mihaela Cosma ◽  
Daniel L. Hurley
Keyword(s):  
Celiac Disease ◽  
Rare Case ◽  
Copper Deficiency

Fuels and Coproducts from Brassica Carinata Oil

2020 ◽  
Author(s):  
Jocelyn Goodwin ◽  
Ed M Coppola
Keyword(s):  
Brassica Carinata

scholarly journals Synthesis of DOTA-pyridine chelates for 64Cu coordination and radiolabeling of αMSH peptide

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Hua Yang ◽  
Feng Gao ◽  
Brooke McNeil ◽  
Chengcheng Zhang ◽  
Zheliang Yuan ◽  
...  
Keyword(s):  
Full Potential ◽  
In Vivo Evaluation ◽  
Melanocortin 1 Receptor ◽  
Melanocyte Stimulating Hormone ◽  
Endogenous Copper ◽  
Coordination Ability ◽  
Copper Chelators ◽  
Cu Complexes ◽  
High Binding Affinity

Abstract Background 64Cu is one of the few radioisotopes that can be used for both imaging and therapy, enabling theranostics with identical chemical composition. Development of stable chelators is essential to harness the potential of this isotope, challenged by the presence of endogenous copper chelators. Pyridyl type chelators show good coordination ability with copper, prompting the present study of a series of chelates DOTA-xPy (x = 1–4) that sequentially substitute carboxyl moieties with pyridyl moieties on a DOTA backbone. Results We found that the presence of pyridyl groups significantly increases 64Cu labeling conversion yield, with DOTA-2Py, −3Py and -4Py quantitatively complexing 64Cu at room temperature within 5 min (1 × 10− 4 M). [64Cu]Cu-DOTA-xPy (x = 2–4) exhibited good stability in human serum up to 24 h. When challenged with 1000 eq. of NOTA, no transmetallation was observed for all three 64Cu complexes. DOTA-xPy (x = 1–3) were conjugated to a cyclized α-melanocyte-stimulating hormone (αMSH) peptide by using one of the pendant carboxyl groups as a bifunctional handle. [64Cu]Cu-DOTA-xPy-αMSH retained good serum stability (> 96% in 24 h) and showed high binding affinity (Ki = 2.1–3.7 nM) towards the melanocortin 1 receptor. Conclusion DOTA-xPy (x = 1–3) are promising chelators for 64Cu. Further in vivo evaluation is necessary to assess the full potential of these chelators as a tool to enable further theranostic radiopharmaceutical development.

scholarly journals Publisher Correction: Origin and hydrodynamics of xylem sap in tree stems, and relationship to root uptake of soil water

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yasunori Mahara ◽  
Tomoko Ohta ◽  
Jyunichi Ohshima ◽  
Kazuya Iizuka
Keyword(s):  
Soil Water ◽  
Xylem Sap ◽  
Root Uptake

scholarly journals Pancytopenia in a child with cystic fibrosis and severe copper deficiency: Insight from bone marrow evaluation

2021 ◽  
Author(s):  
Maggie D. Seblani ◽  
Susanna A. McColley ◽  
Shunyou Gong ◽  
Lee M. Bass ◽  
Sherif M. Badawy
Keyword(s):  
Cystic Fibrosis ◽  
Bone Marrow ◽  
Copper Deficiency ◽  
Bone Marrow Evaluation

scholarly journals Interactive Effects of Nitrogen and Sulfur Nutrition on Growth, Development, and Physiology of Brassica carinata A. Braun and Brassica napus L.

2021 ◽  
Vol 13 (13) ◽  
pp. 7355
Author(s):  
Shivendra Kumar ◽  
Ramdeo Seepaul ◽  
Ian M. Small ◽  
Sheeja George ◽  
George Kelly O’Brien ◽  
...  
Keyword(s):  
Electron Transport ◽  
Leaf Area ◽  
Photosynthetic Pigments ◽  
Net Photosynthesis ◽  
Brassica Carinata ◽  
Internode Length ◽  
Erucic Acid Content ◽  
Total Biomass ◽  
Node Number ◽  
S 100

Brassica carinata (carinata) has emerged as a potential biofuel source due to its high erucic acid content, making it desirable for various industrial applications. Nitrogen (N) and sulfur (S) are required as primary sources of nutrition for growth and development in different oilseed crops and their utilization is interdependent. The purpose of the study was to analyze the interactive effect of N and S nutrition on the growth and other physiological activities of carinata and B. napus (napus). Four treatments, i.e., optimum NS (+N+S, 100% N and 100% S); N limited (−N+S, 0% N, 100% S); S limited (+N−S, 100% N, 0% S), and NS limited (−N−S, 0% N and 0% S) of N and S in full-strength Hoagland solution were imposed in the current study. Effect of different NS treatments was observed on vegetative traits such as number of primary and secondary branches, total leaf area, total biomass production and allocation, and physiological traits such as production of photosynthetic pigments, net photosynthesis, electron transport, and other aspects for both carinata and napus. The traits of stem elongation, number of nodes, node addition rate, internode length, number of primary and secondary branches were 60%, 36%, 50%, 35%, 56%, and 83% lower, respectively, in napus in comparison to carinata. Different NS treatments also positively influenced the production of photosynthetic pigments such as chlorophyll (Chl) a and b and carotenoids in carinata and napus. The concentration of Chla was 11% higher in napus in comparison to carinata. The rate of net photosynthesis, electron transport, and fluorescence was 12%, 8%, and 5% higher based on overall value, respectively, in napus compared to carinata. On the other hand, the overall value for stomatal conductance decreased by 5% in napus when compared to carinata. Different growth-related traits such as vegetative (plant height, node number, internode length, leaf area, number of primary and secondary branches), reproductive (pod number, pod length, seeds per pod), and photosynthetic capacity in oilseed brassicas are correlated with the final seed and oil yield and chemical composition which are of economic importance for the adoption of the crop. Thus, the analysis of these traits will help to determine the effect of NS interaction on crop productivity of carinata and napus.

A case of Menkes syndrome with pyloric stenosis: An effect of copper deficiency on NOS1?

1999 ◽  
Vol 22 (2) ◽  
pp. 197-198 ◽  
Author(s):  
S. Cunningham ◽  
P. M. Crofton ◽  
T. G. Marshall ◽  
D. R. Fitzpatrick
Keyword(s):  
Pyloric Stenosis ◽  
Copper Deficiency ◽  
Effect Of Copper
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