scholarly journals Diagnostic Lumbar Puncture Among Children With Facial Palsy in a Lyme Disease Endemic Area

Author(s):  
Niloufar Paydar-Darian ◽  
Amir A. Kimia ◽  
Paul M. Lantos ◽  
Andrew M. Fine ◽  
Caroline D. Gordon ◽  
...  
Healthcare ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 59 ◽  
Author(s):  
John D. Scott ◽  
Emily L. Pascoe ◽  
Muhammad S. Sajid ◽  
Janet E. Foley

This study provides a novel method of documenting established populations of bird-feeding ticks. Single populations of the blacklegged tick, Ixodes scapularis, and the rabbit tick, Haemaphysalis leporispalustris, were revealed in southwestern Québec, Canada. Blacklegged tick nymphs and, similarly, larval and nymphal rabbit ticks were tested for the Lyme disease bacterium, Borrelia burgdorferi sensu lato (Bbsl), using PCR and the flagellin (flaB) gene, and 14 (42%) of 33 of blacklegged tick nymphs tested were positive. In contrast, larval and nymphal H. leporsipalustris ticks were negative for Bbsl. The occurrence of Bbsl in I. scapularis nymphs brings to light the presence of a Lyme disease endemic area at this songbird nesting locality. Because our findings denote that this area is a Lyme disease endemic area, and I. scapularis is a human-biting tick, local residents and outdoor workers must take preventive measures to avoid tick bites. Furthermore, local healthcare practitioners must include Lyme disease in their differential diagnosis.


1990 ◽  
Vol 19 (4) ◽  
pp. 1061-1065 ◽  
Author(s):  
CHENGXU AI ◽  
RENJIE HU ◽  
KERWIN E. HYLAND ◽  
YUXIN WEN ◽  
YONGGUO ZHANG ◽  
...  

Blood ◽  
2000 ◽  
Vol 96 (10) ◽  
pp. 3381-3384 ◽  
Author(s):  
Amar Gajjar ◽  
Patricia L. Harrison ◽  
John T. Sandlund ◽  
Gaston K. Rivera ◽  
Raul C. Ribeiro ◽  
...  

Abstract The effect of traumatic lumbar puncture at the time of initial diagnostic workup on treatment outcome in children with newly diagnosed acute lymphoblastic leukemia (ALL) was investigated. The findings of the first 2 lumbar punctures performed on 546 patients with newly diagnosed ALL treated on 2 consecutive front-line studies (1984-1991) at St Jude Children's Research Hospital were retrospectively reviewed. Lumbar punctures were performed at the time of diagnosis and again for the instillation of first intrathecal chemotherapy. The event-free survival (EFS) experience for patients with 1 cerebrospinal fluid (CSF) sample contaminated with blast cells was worse than that for patients with no contaminated CSF samples (P = .026); that of patients with 2 consecutive contaminated CSF samples was particularly poor (5-year EFS = 46 ± 9%). In a Cox multiple regression analysis, the strongest prognostic indicator was 2 consecutive contaminated CSF samples, with a hazard ratio of 2.39 (95% confidence interval, 1.36-4.20). These data indicate that contamination of CSF with circulating leukemic blast cells during diagnostic lumbar puncture can adversely affect the treatment outcome of children with ALL and is an indication to intensify intrathecal therapy.


2020 ◽  
Vol 49 (5) ◽  
pp. 887-888
Author(s):  
Jean-Loup Méreaux ◽  
Benjamin Hébant ◽  
Nicolas Magne ◽  
Gérald Quesney ◽  
Romain Lefaucheur

Abstract Lyme disease is an infectious disease caused by the Borrelia burgdorferi spirochetes and other related species that are transmitted through an infected tick bite. We report the case of an older patient presenting with bilateral facial palsy due to Lyme disease. Multiple non-specific clinical signs preceded facial palsy with falls, fatigue and pain of both legs especially during the night. Our case illustrates the difficulty to diagnose this infectious disease, especially in older patients who have rare outdoor activities and a low risk of tick exposure.


Sign in / Sign up

Export Citation Format

Share Document