Concentration-Survival Time Relationship for Roaches Injected with Arsenicals

1945 ◽  
Vol 38 (6) ◽  
pp. 634-642 ◽  
Author(s):  
Sam C. Munson ◽  
J. Franklin Yeager
1948 ◽  
Vol 46 (3) ◽  
pp. 280-288 ◽  
Author(s):  
R. C. Jordan ◽  
S. E. Jacobs

1. The nature of the probit-log survival-time relationship in the disinfection of standard cultures of Bact. coli at 51° C. at pH values ranging from 2·8 to 8·8 has been studied.2. It is concluded that there is a very close approximation to a bilinear form in all cases, though there was evidence that a continuous curve concave upwards and to the left would provide a better fit.3. Probit limits, corresponding to the range of percentage mortality within which, having regard to the experimental error involved, an observation might lie, have been worked out. The range covered by these probit limits decreases as the percentage mortality rises.4. These limits have been used to decide whether a bilinear or a single straight line treatment should be applied to certain sets of data. It is suggested that they would often materially assist in deciding the range over which linearity may be assumed in any given case.


1947 ◽  
Vol 45 (2) ◽  
pp. 144-148 ◽  
Author(s):  
R. C. Jordan ◽  
S. E. Jacobs ◽  
H. E. F. Davies

1. A study has been made of the probit-log survival-time relationship in a number of experiments in which whole standard cultures of Bact. coli were subjected to heat at temperatures ranging from 47 to 55° C.2. It is concluded that the whole mortality up to 99·99 % could not be covered by a single straightline relationship since the graphs are curves concave upwards and to the left.3. Between 95 and 99·99 % mortality the relationship approximated closely to linearity.4. Several individual experiments showed ‘humps’ in their curves. These, although always occurring at the same stage in time in the disinfections, varied in their probit levels.5. By combining the data for all experiments, an idealized probit-log survival-time curve was obtained in which the changes of slope were less marked than in the curve representing the disinfection of similar cultures by phenol.The authors wish to express their gratitude to Messrs I.C.I. (Pharmaceuticals) Ltd. for their valuable financial assistance, which has enabled one of us (H. E. F. D.) to devote his full time to this work.


1966 ◽  
Vol 23 (2) ◽  
pp. 615-622 ◽  
Author(s):  
DONALD J. MUELLER ◽  
ADRIAN P. VAN MONDFRANS ◽  
ADRIAN CHAN ◽  
ROBERT M. W. TRAVERS

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