Field Captures of Wild Melon Fly (Diptera: Tephritidae) with an Improved Male Attractant, Raspberry Ketone Formate

2007 ◽  
Vol 100 (4) ◽  
pp. 1124-1128 ◽  
Author(s):  
Eric B. Jang ◽  
Victor Casana-Giner ◽  
James E. Oliver
Keyword(s):  
Melon Fly ◽  
Raspberry Ketone ◽  
Male Attractant

Syntheses and Behavioral Evaluations of Fluorinated and Silylated Analogs of Raspberry Ketone as Attractants for the Melon Fly, Bactrocera cucurbitae (Coquillett)

2003 ◽  
Vol 38 (1) ◽  
pp. 111-119 ◽  
Author(s):  
V. Casaña-Giner ◽  
J. E. Oliver ◽  
E. Jang ◽  
L. Carvalho
Keyword(s):  
Field Test ◽  
Trimethylsilyl Ether ◽  
Field Tests ◽  
Bactrocera Cucurbitae ◽  
Melon Fly ◽  
Fluorinated Analogs ◽  
Raspberry Ketone

Cuelure, the acetate of raspberry ketone, has for many years been the only practical lure for male melon flies, Bactrocera cucurbitae (Coquillett). Outdoor olfactometer and field tests of several new analogs of raspberry ketone were conducted in Hawaii. Of the newly synthesized compounds, only 4-(4-((trimethylsilanyl)oxy)phenyl)butan-2-one, the trimethylsilyl ether of raspberry ketone, was highly attractive for male melon flies, being statistically equivalent to cuelure in a 2-d field test. None of several fluorinated analogs of raspberry ketone were nearly as attractive as raspberry ketone itself. The recently reported attractant zingerone did not show significant attractiveness to either male or female melon flies.

Raspberry Ketone Formate as an Attractant for the Melon Fly (Diptera: Tephritidae)

2003 ◽  
Vol 38 (1) ◽  
pp. 120-126 ◽  
Author(s):  
Víctor Casaña-Giner ◽  
James E. Oliver ◽  
Eric B. Jang ◽  
Lori Carvalho ◽  
Ashot Khrimian ◽  
...  
Keyword(s):  
Related Compound ◽  
Field Tests ◽  
Bactrocera Cucurbitae ◽  
Melon Fly ◽  
Raspberry Ketone

Cuelure, the acetate of raspberry ketone, has been the standard melon fly (Bactrocera cucurbitae) attractant for at least 40 yrs. A closely related compound, raspberry ketone formate, is somewhat more volatile and has been found to be at least 1.7 times more attractive to both sterile and wild melon flies in field tests conducted in Hawaii, consistently outperforming cuelure for periods exceeding one month.

scholarly journals Genome-wide analysis of long non-coding RNAs in adult tissues of the melon fly, Zeugodacus cucurbitae (Coquillett)

BMC Genomics ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Wei-Jun Li ◽  
Yu-Jia Song ◽  
Hong-Liang Han ◽  
Hui-Qian Xu ◽  
Dong Wei ◽  
...  
Keyword(s):  
Melon Fly ◽  
Genome Wide Analysis ◽  
Adult Tissues ◽  
Genome Wide ◽  
Non Coding Rnas

scholarly journals An ADH toolbox for raspberry ketone production from natural resources via a biocatalytic cascade

2021 ◽  
Author(s):  
Aileen Becker ◽  
Dominique Böttcher ◽  
Werner Katzer ◽  
Karsten Siems ◽  
Lutz Müller-Kuhrt ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Genetically Modified Organisms ◽  
Optical Purity ◽  
High Yield ◽  
Alcohol Dehydrogenases ◽  
Flavor Compound ◽  
Raspberry Ketone ◽  
Cofactor Recycling ◽  
Cosmetic Industry ◽  
Key Points

Abstract Raspberry ketone is a widely used flavor compound in food and cosmetic industry. Several processes for its biocatalytic production have already been described, but either with the use of genetically modified organisms (GMOs) or incomplete conversion of the variety of precursors that are available in nature. Such natural precursors are rhododendrol glycosides with different proportions of (R)- and (S)-rhododendrol depending on the origin. After hydrolysis of these rhododendrol glycosides, the formed rhododendrol enantiomers have to be oxidized to obtain the final product raspberry ketone. To be able to achieve a high conversion with different starting material, we assembled an alcohol dehydrogenase toolbox that can be accessed depending on the optical purity of the intermediate rhododendrol. This is demonstrated by converting racemic rhododendrol using a combination of (R)- and (S)-selective alcohol dehydrogenases together with a universal cofactor recycling system. Furthermore, we conducted a biocatalytic cascade reaction starting from naturally derived rhododendrol glycosides by the use of a glucosidase and an alcohol dehydrogenase to produce raspberry ketone in high yield. Key points • LB-ADH, LK-ADH and LS-ADH oxidize (R)-rhododendrol • RR-ADH and ADH1E oxidize (S)-rhododendrol • Raspberry ketone production via glucosidase and alcohol dehydrogenases from a toolbox Graphical abstract

scholarly journals Refactoring of a synthetic raspberry ketone pathway with EcoFlex

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Simon J. Moore ◽  
Yonek B. Hleba ◽  
Sarah Bischoff ◽  
David Bell ◽  
Karen M. Polizzi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Synthetic Biology ◽  
Combinatorial Libraries ◽  
Value Added ◽  
Microtiter Plate ◽  
Fine Tuning ◽  
Golden Gate ◽  
E Coli ◽  
Fine Chemical ◽  
Raspberry Ketone

Abstract Background  A key focus of synthetic biology is to develop microbial or cell-free based biobased routes to value-added chemicals such as fragrances. Originally, we developed the EcoFlex system, a Golden Gate toolkit, to study genes/pathways flexibly using Escherichia coli heterologous expression. In this current work, we sought to use EcoFlex to optimise a synthetic raspberry ketone biosynthetic pathway. Raspberry ketone is a high-value (~ £20,000 kg−1) fine chemical farmed from raspberry (Rubeus rubrum) fruit. Results  By applying a synthetic biology led design-build-test-learn cycle approach, we refactor the raspberry ketone pathway from a low level of productivity (0.2 mg/L), to achieve a 65-fold (12.9 mg/L) improvement in production. We perform this optimisation at the prototype level (using microtiter plate cultures) with E. coli DH10β, as a routine cloning host. The use of E. coli DH10β facilitates the Golden Gate cloning process for the screening of combinatorial libraries. In addition, we also newly establish a novel colour-based phenotypic screen to identify productive clones quickly from solid/liquid culture. Conclusions  Our findings provide a stable raspberry ketone pathway that relies upon a natural feedstock (L-tyrosine) and uses only constitutive promoters to control gene expression. In conclusion we demonstrate the capability of EcoFlex for fine-tuning a model fine chemical pathway and provide a range of newly characterised promoter tools gene expression in E. coli.

scholarly journals Suppression of cuelure attraction in male Queensland fruit flies provided raspberry ketone supplements as immature adults

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0184086 ◽  
Author(s):  
Humayra Akter ◽  
Saleh Adnan ◽  
Renata Morelli ◽  
Polychronis Rempoulakis ◽  
Phillip W. Taylor
Keyword(s):  
Fruit Flies ◽  
Raspberry Ketone

scholarly journals Suppression of male melon fly Dacus cucurbitae Coquillett (Diptera; Tephritidae) populations using cotton ropes infiltrated with a lure-toxicant.

1988 ◽  
Vol 32 (2) ◽  
pp. 126-128 ◽  
Author(s):  
Masahiro TANIGUCHI ◽  
Hiroaki NAKAMORI ◽  
Hiroyuki KAKINOHANA ◽  
Yoshio YOGI ◽  
Hiroshi ZUKEYAMA
Keyword(s):  
Melon Fly
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