scholarly journals Effects of fermented Chinese herbal medicines on milk performance and immune function in late-lactation cows under heat stress conditions

Author(s):  
C H Shan ◽  
J J Guo ◽  
X S Sun ◽  
N Li ◽  
X Y Yang ◽  
...  
2020 ◽  
Author(s):  
Julien S. Baker ◽  
Zhaoxiang Bian ◽  
Wei Jia ◽  
Yike Guo ◽  
Yang Gao ◽  
...  

BACKGROUND Recent studies revealed that most discharged patients with COVID-19 suffered ongoing symptoms months later. Rehabilitation interventions can help address the consequences of COVID-19. These include medically, physically, cognitively and psychologically related problems. To our knowledge, no studies have investigated the effects of rehabilitation following discharge from hospital. OBJECTIVE The specific aims of this project are to investigate the effects of a 12-week exercise program on pulmonary fibrosis in recovering COVID-19 patients. A further aim will be to examine how Chinese herbal medicines, gut microbiome and its metabolites regulate immune function and possibly autoimmune deficiency in the rehabilitation process. METHODS In this triple-blinded, randomized, parallel groups, controlled clinical trial, we will recruit adult patients with COVID-19 who have been discharged from the hospital in Hong Kong and are suffering from impaired lung function and pulmonary function. A total of 172 eligible patients will be randomized into four equal groups: 1) cardiorespiratory exercise plus Chinese herbal medicines group, 2) cardiorespiratory exercise only group, 3) Chinese herbal medicines only group and 4) waiting list group (in which participants will receive Chinese herbal medicines after 24 weeks). These treatments will be administered for 12 weeks with a 12-week follow-up period. Primary outcomes include dyspnea, fatigue, lung function, pulmonary function, blood oxygen levels, immune function, blood coagulation, and related blood biochemistry. Measurements will be recorded prior to initiating the above treatments and repeated at the 13th and 25th weeks of the study. The primary analysis is aimed at comparing the outcomes between groups throughout the study period with alpha level of 0.05 (two-tailed). RESULTS The trial has not been recruiting patients. The proposed study will be completed in 24 months from 01 Jan 2021 to 31 Dec 2022. CONCLUSIONS NA CLINICALTRIAL ClinicalTrials.gov NCT04572360; https://clinicaltrials.gov/ct2/show/NCT04572360


Scientifica ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Parisa Shokryazdan ◽  
Mohammad Faseleh Jahromi ◽  
Salwani MD Saadand ◽  
Mahdi Ebrahimi ◽  
Zulkifli Idrus ◽  
...  

Heat stress negatively affects the productivity of chickens in commercial poultry farms in humid tropics. In this study, the concentrations and types of the antioxidant compounds of eight Chinese herbal medicines, which have previously demonstrated promising effects on suppressing heat stress as a mixture, were investigated using reversed-phase High Performance Liquid Chromatography, spectrophotometry, Liquid Chromatography Mass Spectrometry, and Gas-Liquid Chromatography. Our results provided the levels of phenolic compounds, total amounts of sugars, and total unsaturated fatty acids in the herbal extracts. Apart from the detection and quantification of the active ingredients of herbs that have the potential to mitigate heat stress in poultry, results of this study also provide useful data for developing an efficient and accurate formulation of the herbs’ mixtures in order to induce positive effects against heat stress in in vivo studies.


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