scholarly journals Molecular characterization of carbapenem-resistant Escherichia coli and Acinetobacter baumannii in the Lao People’s Democratic Republic

2019 ◽  
Vol 74 (9) ◽  
pp. 2810-2821 ◽  
Author(s):  
Tomas-Paul Cusack ◽  
Vilayouth Phimolsarnnousith ◽  
Khuanta Duangmala ◽  
Phonelavanh Phoumin ◽  
Jane Turton ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Acinetobacter Baumannii ◽  
Molecular Characterization ◽  
Democratic Republic ◽  
Lao People’S Democratic Republic ◽  
Lao People's Democratic Republic ◽  
Carbapenem Resistant

scholarly journals Molecular characterization of Carbapenem resistant Escherichia coli recovered from a tertiary hospital in Lebanon

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203323 ◽  
Author(s):  
Christel Dagher ◽  
Tamara Salloum ◽  
Sahar Alousi ◽  
Harout Arabaghian ◽  
George F. Araj ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Molecular Characterization ◽  
Tertiary Hospital ◽  
Carbapenem Resistant

scholarly journals Molecular Characterization of Invasive Carbapenem-Resistant Acinetobacter baumannii from a Tertiary Care Hospital in South India

2016 ◽  
Vol 5 (3) ◽  
pp. 379-387 ◽  
Author(s):  
Saranya Vijayakumar ◽  
Radha Gopi ◽  
Priya Gunasekaran ◽  
Manjurekar Bharathy ◽  
Kamini Walia ◽  
...  
Keyword(s):  
Acinetobacter Baumannii ◽  
Molecular Characterization ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Carbapenem Resistant

scholarly journals Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates from Egyptian Patients

2020 ◽  
Author(s):  
Reem M Hassan ◽  
Sherifa T Salem ◽  
Saly Ismail Mostafa Hassan ◽  
Asmaa Hegab ◽  
Yasmine S Elkholy
Keyword(s):  
Acinetobacter Baumannii ◽  
Molecular Characterization ◽  
Antimicrobial Agents ◽  
Treatment Options ◽  
Carbapenem Resistance ◽  
Common Mechanism ◽  
Carbapenem Resistant ◽  
Egyptian Patients ◽  
Global Threat

Abstract Acinetobacter baumannii (A. baumannii) represents a global threat owing to its ability to resist most of the currently available antimicrobial agents. Moreover, emergence of carbapenem resistant A. baumannii (CR-AB) isolates limits the available treatment options. Enzymatic degradation by variety of ß-lactamases, have been identified as the most common mechanism of carbapenem resistance in A. baumannii. The alarming increase in the prevalence of CR-AB necessitates continuous screening and molecular characterization to appreciate the problem. The present study was performed to assess the prevalence and characterize carbapenemases among 206 CR-AB isolated from various clinical specimens collected from different intensive care units at Kasr Al-Aini Hospital. All isolates were confirmed to be A. baumannii by detection of the blaOXA-51-like gene. Molecular screening of 13 common Ambler class bla carbapenemases genes in addition to insertion sequence (IS-1) upstream OXA-23 was performed by using four sets of multiplex PCR, followed by identification using gene sequencing technology. Among the investigated genes, the prevalence of blaOXA-23, and blaOXA-58 were 77.7%, and 1.9%, respectively. The ISAba1 was detected in 10% of the blaOXA-23 positive isolates. The prevalence of metallo-β-lactamases (MBLs) studied; blaNDM-1, blaSPM, blaVIM, blaSIM-1 were 11.7%, 6.3%, 0.5%, and 0.5% respectively. One of class A; bla KPC was detected in 10.7% of the investigated isolates. blaOXA-24/40, blaIMP, blaGES, blaVEB and blaGIM were not detected in any of the studied isolates. Moreover, 18.4% of the isolates have shown to harbor two or more of the screened bla genes. We concluded that the most prevalent type of ß-lactamases genes among CR-AB isolates collected from Egyptian patients were blaOXA-23 followed by blaNDM-1 and blaKPC.

scholarly journals Characteristics of CTX-M ESBL-producing Escherichia coli isolates from the Lao People's Democratic Republic, 2004-09

2011 ◽  
Vol 67 (1) ◽  
pp. 240-242 ◽  
Author(s):  
N. Stoesser ◽  
D. W. Crook ◽  
C. E. Moore ◽  
R. Phetsouvanh ◽  
V. Chansamouth ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Democratic Republic ◽  
Lao People’S Democratic Republic ◽  
Lao People's Democratic Republic
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