Antibiotic resistance of Enterobacteriaceae causing urinary tract infections in elderly patients living in the community and in the nursing home: a retrospective observational study

2018 ◽  
Vol 74 (3) ◽  
pp. 775-781 ◽  
Author(s):  
Céline Pulcini ◽  
Isabelle Clerc-Urmes ◽  
Cossi Angelo Attinsounon ◽  
Sébastien Fougnot ◽  
Nathalie Thilly
Keyword(s):  
Antibiotic Resistance ◽  
Nursing Home ◽  
Urinary Tract ◽  
Observational Study ◽  
Elderly Patients ◽  
Urinary Tract Infections ◽  
Retrospective Observational Study ◽  
Tract Infections

scholarly journals Antibiotic Resistance and Virulence Phenotypes of Recent Bacterial Strains Isolated from Urinary Tract Infections in Elderly Patients with Prostatic Disease

Pathogens ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 22 ◽  
Author(s):  
Cristina Delcaru ◽  
Paulina Podgoreanu ◽  
Ionela Alexandru ◽  
Nela Popescu ◽  
Luminiţa Măruţescu ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Elderly Patients ◽  
Urinary Tract Infections ◽  
Bacterial Strains ◽  
Prostatic Disease ◽  
Tract Infections

scholarly journals Nitrofurantoin Failure in Elderly Men: A Retrospective Observational Study

Antibiotics ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 211
Author(s):  
Ilse Wolterink ◽  
Theo Verheij ◽  
Tamara Platteel ◽  
Ann van den Bruel ◽  
Arjen Stam ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Observational Study ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
The Elderly ◽  
Retrospective Observational Study ◽  
Elderly Men ◽  
First Choice ◽  
And Gender ◽  
Tract Infections

Urinary tract infections in the elderly are common. Treatment with nitrofurantoin in men may not be sufficient if concomitant tissue involvement is present, resulting in treatment failure. The aim of this study is to determine the prevalence of nitrofurantoin failure in the elderly, and to assess the effect of gender and age. A retrospective observational study was conducted using a Dutch general practice medical record database of 21,789 men and 26,622 women aged 65 years or older in 2015. First, nitrofurantoin prescriptions in 2015 were analyzed. Nitrofurantoin failure (subsequent prescription of antibiotic within 30 days) for men, women, and different age categories were compared. The effect of age and gender was assessed using multivariate logistic regression. A total of 3537 patients had a first nitrofurantoin prescription in 2015; 506 men and 3031 women. Overall, 584 patients (17%) experienced nitrofurantoin failure; 135 (27%) men and 449 (15%) women. Male gender (odds ratio (OR) = 2.09, 95% confidence interval (CI) 1.68–2.61) and age (OR = 1.02, 95% CI 1.01–1.03) was associated with higher treatment failure. Our findings indicate that in a substantial number of elderly men, nitrofurantoin might not be the appropriate treatment. Nitrofurantoin, as a first choice in elderly men with urinary tract infections, should be reconsidered.

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