Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure–response relationships

Anke E Kip; María del Mar Castro; Maria Adelaida Gomez; Alexandra Cossio; Jan H M Schellens; Jos H Beijnen; Nancy Gore Saravia; Thomas P C Dorlo

doi:10.1093/jac/dky143

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure–response relationships

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dky143 ◽

2018 ◽

Vol 73 (8) ◽

pp. 2104-2111 ◽

Cited By ~ 4

Author(s):

Anke E Kip ◽

María del Mar Castro ◽

Maria Adelaida Gomez ◽

Alexandra Cossio ◽

Jan H M Schellens ◽

...

Keyword(s):

Cutaneous Leishmaniasis ◽

New World ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Exposure Response ◽

Population Pharmacokinetic Modelling

Download Full-text

Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2011.04108.x ◽

2012 ◽

Vol 73 (3) ◽

pp. 391-401 ◽

Cited By ~ 20

Author(s):

Cornelia B. Landersdorfer ◽

Yan-Ling He ◽

William J. Jusko

Keyword(s):

Tight Binding ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase Iv ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling

Download Full-text

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability

British Journal of Clinical Pharmacology ◽

10.1046/j.1365-2125.2003.01967.x ◽

2003 ◽

Vol 56 (6) ◽

pp. 639-652 ◽

Cited By ~ 42

Author(s):

Thomas Kerbusch ◽

Ulrika Wählby ◽

Peter A. Milligan ◽

Mats O. Karlsson

Keyword(s):

Population Pharmacokinetic ◽

Cyp2d6 Genotype ◽

Pharmacokinetic Modelling ◽

Pooled Data ◽

Population Pharmacokinetic Modelling ◽

First Pass Metabolism ◽

First Pass ◽

Hydroxylated Metabolite ◽

Pass Metabolism

Download Full-text

Population pharmacokinetic modelling of indium-based quantum dot nanoparticles: preclinical in vivo studies

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2020.105639 ◽

2021 ◽

Vol 157 ◽

pp. 105639

Author(s):

Elnaz Yaghini ◽

Elisa Tacconi ◽

Andrew Pilling ◽

Paula Rahman ◽

Joe Broughton ◽

...

Keyword(s):

Quantum Dot ◽

In Vivo Studies ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling

Download Full-text

Integrated population pharmacokinetic modelling of liposomal irinotecan in patients with various tumour types, including untreated metastatic pancreatic cancer (mPC)

Annals of Oncology ◽

10.1093/annonc/mdz247.018 ◽

2019 ◽

Vol 30 ◽

pp. v263 ◽

Cited By ~ 1

Author(s):

T. Macarulla ◽

K. Brendel ◽

C. Lieu ◽

Z. Wainberg ◽

F. Dayyani ◽

...

Keyword(s):

Pancreatic Cancer ◽

Metastatic Pancreatic Cancer ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling ◽

Liposomal Irinotecan

Download Full-text

Population pharmacokinetic modelling and simulation of single and multiple dose administration of meloxicam in cats

Journal of Veterinary Pharmacology and Therapeutics ◽

10.1111/j.1365-2885.2009.01134.x ◽

2009 ◽

Vol 33 (3) ◽

pp. 277-286 ◽

Cited By ~ 17

Author(s):

T. LEHR ◽

R. NARBE ◽

O. JÖNS ◽

C. KLOFT ◽

A. STAAB

Keyword(s):

Multiple Dose ◽

Modelling And Simulation ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Dose Administration ◽

Population Pharmacokinetic Modelling ◽

Multiple Dose Administration

Download Full-text

Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach

British Journal of Clinical Pharmacology ◽

10.1111/bcp.12118 ◽

2013 ◽

Vol 76 (6) ◽

pp. 868-879 ◽

Cited By ~ 26

Author(s):

Christian Bartels ◽

Michael Looby ◽

Romain Sechaud ◽

Guenther Kaiser

Keyword(s):

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling ◽

Modelling Approach

Download Full-text

Population pharmacokinetic modelling of repaglinide in healthy volunteers by using Non-Parametric Adaptive Grid Algorithm

Journal of Clinical Pharmacy and Therapeutics ◽

10.1111/j.1365-2710.2009.01042.x ◽

2010 ◽

Vol 35 (1) ◽

pp. 105-112 ◽

Cited By ~ 2

Author(s):

A. B. Ruzilawati ◽

A. W. Mohd Suhaimi ◽

S. H. Gan

Keyword(s):

Healthy Volunteers ◽

Adaptive Grid ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling ◽

Grid Algorithm ◽

Non Parametric

Download Full-text

Population pharmacokinetic modelling of total and unbound cefazolin plasma concentrations as a guide for dosing in preterm and term neonates

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkt527 ◽

2014 ◽

Vol 69 (5) ◽

pp. 1330-1338 ◽

Cited By ~ 20

Author(s):

R. F. W. De Cock ◽

A. Smits ◽

K. Allegaert ◽

J. de Hoon ◽

V. Saegeman ◽

...

Keyword(s):

Plasma Concentrations ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Term Neonates ◽

Population Pharmacokinetic Modelling

Download Full-text

Pharmacodynamic evaluation of biapenem in peritoneal fluid using population pharmacokinetic modelling and Monte Carlo simulation

International Journal of Antimicrobial Agents ◽

10.1016/j.ijantimicag.2008.03.011 ◽

2008 ◽

Vol 32 (4) ◽

pp. 339-343 ◽

Cited By ~ 6

Author(s):

Kazuro Ikawa ◽

Norifumi Morikawa ◽

Kayo Ikeda ◽

Hiroki Ohge ◽

Taijiro Sueda

Keyword(s):

Monte Carlo Simulation ◽

Monte Carlo ◽

Peritoneal Fluid ◽

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling

Download Full-text

Population pharmacokinetic modelling and evaluation of different dosage regimens for darunavir and ritonavir in HIV-infected individuals

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dku131 ◽

2014 ◽

Vol 69 (9) ◽

pp. 2489-2498 ◽

Cited By ~ 25

Author(s):

M. Arab-Alameddine ◽

R. Lubomirov ◽

A. Fayet-Mello ◽

M. Aouri ◽

M. Rotger ◽

...

Keyword(s):

Population Pharmacokinetic ◽

Pharmacokinetic Modelling ◽

Population Pharmacokinetic Modelling ◽

Dosage Regimens

Download Full-text