scholarly journals Factors associated with virological response to a switch regimen containing maraviroc for antiretroviral-experienced HIV-1-infected patients

2016 ◽  
Vol 71 (9) ◽  
pp. 2651-2653 ◽  
Author(s):  
L. Bocket ◽  
G. Peytavin ◽  
E. K. Alidjinou ◽  
F. Ajana ◽  
P. Choisy ◽  
...  
Keyword(s):  
Virological Response ◽  
Factors Associated ◽  
Switch Regimen ◽  
Hiv 1

scholarly journals Antiretroviral-Experienced HIV-1-Infected Patients Treated with Maraviroc: Factors Associated with Virological Response

2015 ◽  
Vol 31 (5) ◽  
pp. 475-478 ◽  
Author(s):  
Cathia Soulie ◽  
Gilles Peytavin ◽  
Charlotte Charpentier ◽  
Sidonie Lambert-Niclot ◽  
Sophie Sayon ◽  
...  
Keyword(s):  
Virological Response ◽  
Factors Associated ◽  
Hiv 1

scholarly journals Factors Associated with Virological Response to Etravirine in Nonnucleoside Reverse Transcriptase Inhibitor-Experienced HIV-1-Infected Patients

2009 ◽  
Vol 54 (1) ◽  
pp. 72-77 ◽  
Author(s):  
Anne-Genevieve Marcelin ◽  
Philippe Flandre ◽  
Diane Descamps ◽  
Laurence Morand-Joubert ◽  
Charlotte Charpentier ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Virological Response ◽  
New Drugs ◽  
Resistance Mutations ◽  
Reverse Transcriptase Inhibitors ◽  
Cd4 Cell Count ◽  
Factors Associated ◽  
The Impact ◽  
First Time ◽  
Hiv 1

ABSTRACT To identify factors associated with virological response (VR) to an etravirine (ETR)-based regimen, 243 patients previously treated with nonnucleoside reverse transcriptase inhibitors (NNRTIs) were studied. The impact of baseline HIV-1 RNA, CD4 cell count, past NNRTIs used, 57 NNRTI resistance mutations, genotypic sensitivity score (GSS) for nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), and the number of new drugs used with ETR for the first time on the VR to an ETR regimen were investigated. Among the 243 patients, the median baseline HIV-1 RNA level was 4.4 log10 copies/ml (interquartile range [IQR], 3.7 to 4.9) and the median CD4 count was 175 cells/mm3 (IQR, 69 to 312). Patients had been previously exposed to a median of 6 NRTIs, 1, NNRTI, and 5 PIs. Overall, 82% of patients achieved a VR at month 2, as defined by a decrease of at least 1.5 log10 copies/ml and/or HIV-1 RNA level of <50 copies/ml. No difference in VR was observed between patients receiving or not a boosted PI in combination with ETR. Factors independently associated with a better VR to ETR were the number of drugs (among enfuvirtide, darunavir, or raltegravir) used for the first time in combination with ETR and the presence of the K103N mutation at baseline. Mutations Y181V and E138A were independently associated with poor VR, whereas no effect of the Y181C on VR was observed. In conclusion, ETR was associated with high response rates in NNRTI-experienced patients in combination with other active drugs regardless of the therapeutic class used.

A cohort study of treatment-experienced HIV-1-infected patients treated with raltegravir: factors associated with virological response and mutations selected at failure

2013 ◽  
Vol 42 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Anne-Geneviève Marcelin ◽  
Constance Delaugerre ◽  
Céline Beaudoux ◽  
Diane Descamps ◽  
Laurence Morand-Joubert ◽  
...  
Keyword(s):  
Cohort Study ◽  
Virological Response ◽  
Factors Associated ◽  
Hiv 1

scholarly journals HIV-1 prevalence and factors associated with infection in the conflict-affected region of North Uganda

2007 ◽  
Vol 1 (1) ◽  
Author(s):  
Massimo Fabiani ◽  
Barbara Nattabi ◽  
Chiara Pierotti ◽  
Filippo Ciantia ◽  
Alex A Opio ◽  
...  
Keyword(s):  
Factors Associated ◽  
Hiv 1

Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients

AIDS ◽  
2002 ◽  
Vol 16 (14) ◽  
pp. 1867-1876 ◽  
Author(s):  
Andrea Antinori ◽  
Maria Letizia Giancola ◽  
Susanna Grisetti ◽  
Fabio Soldani ◽  
Lucia Alba ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Virological Response ◽  
Antiretroviral Drugs ◽  
Factors Influencing ◽  
Hiv 1

Factors Associated With Knee Osteoarthritis in an Outpatient HIV-1 Clinic Setting

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Benjamin S. Naovarat ◽  
Marka A. Lyons ◽  
Jonathan D. Dau ◽  
Binh Y. Nguyen ◽  
Gloria A. Salazar ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Factors Associated ◽  
Clinic Setting ◽  
Hiv 1

scholarly journals Factors Associated With CD8+ T-Cell Activation in HIV-1–Infected Patients on Long-term Antiretroviral Therapy

2014 ◽  
Vol 67 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Lu Zheng ◽  
Babafemi Taiwo ◽  
Rajesh T. Gandhi ◽  
Peter W. Hunt ◽  
Ann C. Collier ◽  
...  
Keyword(s):  
T Cell ◽  
Antiretroviral Therapy ◽  
T Cell Activation ◽  
Cell Activation ◽  
Cd8 T Cell ◽  
Factors Associated ◽  
Hiv 1

scholarly journals Factors Associated With Virological Failure in HIV-1–Infected Patients Receiving Darunavir/Ritonavir Monotherapy

2011 ◽  
Vol 204 (8) ◽  
pp. 1211-1216 ◽  
Author(s):  
Sidonie Lambert-Niclot ◽  
Philippe Flandre ◽  
Marc-Antoine Valantin ◽  
Gilles Peytavin ◽  
Claudine Duvivier ◽  
...  
Keyword(s):  
Virological Failure ◽  
Factors Associated ◽  
Hiv 1
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