scholarly journals Risk factors for acute kidney injury (AKI) in patients treated with polymyxin B and influence of AKI on mortality: a multicentre prospective cohort study

2015 ◽  
Vol 70 (5) ◽  
pp. 1552-1557 ◽  
Author(s):  
Maria Helena Rigatto ◽  
Tainá F. Behle ◽  
Diego R. Falci ◽  
Thiela Freitas ◽  
Natane T. Lopes ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Kidney Injury ◽  
Polymyxin B

scholarly journals Risk Factors and Outcome of Acute Kidney Injury after Isolated CABG Surgery: a Prospective Cohort Study

2019 ◽  
Vol 34 (1) ◽  
Author(s):  
Shahram Amini ◽  
Mona Najaf Najafi ◽  
Seyedeh Parissa Karrari ◽  
Mohammadghasem Etemadi Mashhadi ◽  
Sahereh Mirzaei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Kidney Injury ◽  
Cabg Surgery

Incidence, Risk Factors, and Outcomes of Transition of Acute Kidney Injury to Chronic Kidney Disease in Cirrhosis: A Prospective Cohort Study

Hepatology ◽  
2019 ◽  
Vol 71 (3) ◽  
pp. 1009-1022 ◽  
Author(s):  
Rakhi Maiwall ◽  
Samba Siva Rao Pasupuleti ◽  
Chhagan Bihari ◽  
Archana Rastogi ◽  
Pawan Kumar Singh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Cohort Study ◽  
Kidney Disease ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Kidney Injury ◽  
Incidence Risk

scholarly journals Incidence, Risk Factors, and Outcomes of Neonatal Acute Kidney Injury: Protocol of a Multicentric Prospective Cohort Study [The Indian Iconic Neonatal Kidney Educational Registry]

2021 ◽  
Vol 9 ◽  
Author(s):  
Gopal Agrawal ◽  
Sanjay Wazir ◽  
Sidharth Kumar Sethi ◽  
Abhishek Tibrewal ◽  
Rohan Dhir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Data Entry ◽  
Kidney Injury ◽  
Data Repository ◽  
Discharge Data ◽  
Neonatal Kidney

Background: Acute kidney injury (AKI) is a significant problem in neonates, but the evidence is sparse. Neonatal AKI is an independent risk factor for increased mortality and prolonged hospital stay. There are stark differences in the epidemiology of AKI in neonates amongst the developing and the developed world. Increased prevalence of neonatal sepsis, lack of awareness about neonatal AKI and poor access to pediatric nephrologists add to the improper management of neonatal AKI in the developing countries.Methods: This study is a multicentric, national, prospective cohort study [The Indian iconic Neonatal Kidney Educational Registry (TINKER)] conducted in level 2–3 NICUs in 11 centers across India. We have enrolled nearly 2,000 neonates over the study period. Neonates (≤ 28 days) who were admitted in NICU and those who received intravenous (IV) fluids for at least 48 h for hydration and/or nutrition have been included. Data collection included: (1) baseline demographics (2) daily physiologic and laboratory parameters (3) discharge data. KDIGO workgroup AKI definition modified for neonates was used for defining AKI. Data entry was carried out by individual participating centers using a web-based database (akiregistry.org). De-identified data has been maintained and handled by the principal investigator (PI). This collaboration plans to disseminate data through peer-reviewed publications and through presentations at educational conferences.Conclusions: The purpose of this study is to create the first prospective neonatal all-cause AKI data repository and describe the incidence of neonatal AKI in NICUs in the country and determine the risk factors as well as the outcomes of such neonates—both short-term and long-term outcomes. This will eventually spur therapeutic advancements, facilitate decipherment of epidemiological trends, risk factors as well as outcomes and identify disparities in management across the nation.

Incidence, risk factors, and outcome of neonatal acute kidney injury: a prospective cohort study

2018 ◽  
Vol 33 (9) ◽  
pp. 1617-1624 ◽  
Author(s):  
Mohamed A. Shalaby ◽  
Zinab A. Sawan ◽  
Esraa Nawawi ◽  
Saad Alsaedi ◽  
Heidi Al-Wassia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Kidney Injury ◽  
Incidence Risk

Urinary exosomal CD26 is associated with recovery from acute kidney injury in intensive care units: a prospective cohort study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Juan Du ◽  
Yihui Li ◽  
Qiang Sun ◽  
Zhihao Wang ◽  
Feng Wang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Kidney Injury ◽  
Prediction Performance ◽  
Control Cohort ◽  
Clinical Factors ◽  
Qilu Hospital ◽  
Major Adverse Kidney Events

Abstract Objectives Currently there is no validated method to predict renal reversal and recovery after acute kidney injury (AKI). As exosomes have the potential for AKI prognosis and CD26 is involved in the mechanisms in AKI, this study aims to investigate whether urinary exosomal CD26 is associated with renal-related outcomes and explore its prospect as a novel prognosis biomarker. Methods This was a single-center, prospective cohort study. A total of 133 AKI patients and 68 non-AKI patients admitted to ICU in Qilu Hospital Shandong University from January 2017 to January 2018. Urine samples were collected at enrollment and the relative expression of CD26 (CD26 percentage) in urinary exosomes was examined, that was then categorized into a low-CD26 level and a high-CD26 level. Results CD26 percentage was significantly lower in the AKI cohort than in the control cohort. Within the AKI cohort, a high-CD26 level was associated with lower incidence of major adverse kidney events within 90 days, but higher incidence of reversal within 28 days. In AKI survivors, a high-CD26 level had a 4.67-, 3.50- and 4.66-fold higher odds than a low-CD26 level for early reversal, recovery and reversal, respectively, after adjustment for clinical factors. Prediction performance was moderate for AKI survivors but improved for non-septic AKI survivors. Conclusions Urinary exosomal CD26 is associated with renal reversal and recovery from AKI and is thus a promising prognosis biomarker.

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