Selection for qacA carriage in CC22, but not CC30, methicillin-resistant Staphylococcus aureus bloodstream infection isolates during a successful institutional infection control programme

2013 ◽  
Vol 68 (5) ◽  
pp. 992-999 ◽  
Author(s):  
Jonathan A. Otter ◽  
Amita Patel ◽  
Penelope R. Cliff ◽  
Eugene P. Halligan ◽  
Olga Tosas ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Infection Control ◽  
Bloodstream Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Control Programme ◽  
Methicillin Resistant ◽  
Staphylococcus Aureus Bloodstream Infection ◽  
Selection For ◽  
Infection Control Programme

scholarly journals Methicillin-resistant Staphylococcus aureus bloodstream infection: risk factors and clinical outcome in non-intensive-care units

2012 ◽  
Vol 45 (2) ◽  
pp. 189-193 ◽  
Author(s):  
Karinne Spirandelli Carvalho Naves ◽  
Natália Vaz da Trindade ◽  
Paulo Pinto Gontijo Filho
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Bloodstream Infection ◽  
Antimicrobial Agents ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistance ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Methicillin Resistant ◽  
Staphylococcus Aureus Bloodstream Infection

INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is spread out in hospitals across different regions of the world and is regarded as the major agent of nosocomial infections, causing infections such as skin and soft tissue pneumonia and sepsis. The aim of this study was to identify risk factors for methicillin-resistance in Staphylococcus aureus bloodstream infection (BSI) and the predictive factors for death. METHODS: A retrospective cohort of fifty-one patients presenting bacteraemia due to S. aureus between September 2006 and September 2008 was analysed. Staphylococcu aureus samples were obtained from blood cultures performed by clinical hospital microbiology laboratory from the Uberlândia Federal University. Methicillinresistance was determined by growth on oxacillin screen agar and antimicrobial susceptibility by means of the disk diffusion method. RESULTS: We found similar numbers of MRSA (56.8%) and methicillin-susceptible Staphylococcus aureus (MSSA) (43.2%) infections, and the overall hospital mortality ratio was 47%, predominantly in MRSA group (70.8% vs. 29.2%) (p=0.05). Age (p=0.02) was significantly higher in MRSA patients as also was the use of central venous catheter (p=0.02). The use of two or more antimicrobial agents (p=0.03) and the length of hospital stay prior to bacteraemia superior to seven days (p=0.006) were associated with mortality. High odds ratio value was observed in cardiopathy as comorbidity. CONCLUSIONS: Despite several risk factors associated with MRSA and MSSA infection, the use of two or more antimicrobial agents was the unique independent variable associated with mortality.

scholarly journals Methicillin-Resistant Staphylococcus aureus Bloodstream Infection Surveillance: National Healthcare Safety Network’s Laboratory-Identified Event Reporting versus Traditional Laboratory-Confirmed Bloodstream Infection Surveillance

2014 ◽  
Vol 35 (10) ◽  
pp. 1286-1289 ◽  
Author(s):  
Arthur W. Baker ◽  
Michael J. Durkin ◽  
Kristen V. Dicks ◽  
Sarah S. Lewis ◽  
Rebekah W. Moehring ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Bloodstream Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Healthcare Facility ◽  
Event Reporting ◽  
Methicillin Resistant ◽  
National Healthcare ◽  
Infection Surveillance ◽  
Staphylococcus Aureus Bloodstream Infection ◽  
Traditional Surveillance

Hospitals must report cases of methicillin-resistant Staphylococcus aureus bloodstream infection (BSI) using a new laboratory-identified (LabID) event reporting module. BSI rates obtained using LabID differ from rates of BSI obtained from traditional surveillance (concordance of healthcare facility–onset cases, 61%–76%) because definitions used to report LabID events are inconsistent with traditional BSI definitionsInfect Control Hosp Epidemiol 2014;35(10):1286–1289

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