scholarly journals In vivo efficacy of telithromycin on cytokine and nitric oxide formation in lipopolysaccharide-induced acute systemic inflammation in mice

2006 ◽  
Vol 58 (3) ◽  
pp. 615-621 ◽  
Author(s):  
K. Lotter
Keyword(s):  
Nitric Oxide ◽  
Systemic Inflammation ◽  
Oxide Formation ◽  
In Vivo Efficacy ◽  
Nitric Oxide Formation

In vivo monitoring of radiation-induced hepatic nitric oxide formation. Inhibition by antioxidants

1998 ◽  
Vol 25 ◽  
pp. S108
Author(s):  
Hong Sang ◽  
Yashige Kotake ◽  
Danny R. Moore ◽  
Lester A. Reinke ◽  
Toshihiko Ozawa
Keyword(s):  
Nitric Oxide ◽  
Oxide Formation ◽  
In Vivo Monitoring ◽  
Nitric Oxide Formation ◽  
Radiation Induced

Tempol Enhances the Nitrite-derived Nitric oxide Formation in Vitro and in Vivo

2010 ◽  
Vol 49 ◽  
pp. S14
Author(s):  
Jefferson Henrich Amaral ◽  
Marcelo Montenegro ◽  
Lucas Pinheiro ◽  
Graziele Ferreira ◽  
Jose Eduardo Tanus Santos
Keyword(s):  
Nitric Oxide ◽  
Oxide Formation ◽  
Nitric Oxide Formation

Inhibition of nitric oxide formation in vivo enhances superoxide release by the perfused liver

1994 ◽  
Vol 266 (5) ◽  
pp. G783-G788 ◽  
Author(s):  
A. P. Bautista ◽  
J. J. Spitzer
Keyword(s):  
Nitric Oxide ◽  
Superoxide Anion ◽  
Tissue Injury ◽  
Protective Mechanism ◽  
Perfused Liver ◽  
Oxide Formation ◽  
Free Radical Damage ◽  
Nitric Oxide Formation ◽  
Superoxide Release

Nitric oxide, a known scavenger of toxic oxygen-derived radicals, has been shown to have a protective effect against tissue injury in endotoxemia. Based on the hypothesis that under normal physiological conditions, a balance between superoxide and nitric oxide exists in vivo, this work examines hepatic superoxide release after nitric oxide formation is inhibited in vivo. Male Sprague-Dawley rats were treated intravenously with N omega-nitro-L-arginine methyl ester (L-NAME; 50 mg/kg body wt), an inhibitor of nitric oxide synthase. One hour later, superoxide anion release by the perfused liver was determined. Results show that a significant amount of superoxide was released after L-NAME treatment. Likely sources of this radical are the Kupffer cells. Inhibition of nitric oxide formation in vivo did not enhance superoxide release by hepatocytes or sinusoidal endothelial cells. The effect of L-NAME treatment on superoxide release in endotoxemic rats was also examined 12 h after lipopolysaccharide treatment, when toxic oxygen-derived radical formation could not be detected. Inhibition of nitric oxide release in vivo in these rats enhanced the formation of superoxide anion. The interaction between nitric oxide and superoxide anion under normal conditions may represent an important protective mechanism of the host against free radical damage.

P43. Tempol enhances the nitrite-derived nitric oxide formation in vitro and in vivo

Nitric Oxide ◽  
2011 ◽  
Vol 24 ◽  
pp. S31
Author(s):  
Jefferson Amaral ◽  
Marcelo Montenegro ◽  
Lucas Pinheiro ◽  
Graziele Ferreira ◽  
José Eduardo Tanus-Santos
Keyword(s):  
Nitric Oxide ◽  
Oxide Formation ◽  
Nitric Oxide Formation

Nitric oxide formation in the dog sphincter of Oddi from nitric oxide donors as measured with in vivo micro-dialysis

2000 ◽  
Vol 14 (8) ◽  
pp. 1095-1101 ◽  
Author(s):  
I. Yamamoto ◽  
M. Fujimura ◽  
N. Kihara ◽  
K. Kumano ◽  
T. Yamada ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sphincter Of Oddi ◽  
Nitric Oxide Donors ◽  
Oxide Formation ◽  
Nitric Oxide Formation

URINARY NO3− EXCRETION AS AN INDICATOR OF NITRIC OXIDE FORMATION IN VIVO DURING ORAL ADMINISTRATION OF l-ARGININE OR l-NAME IN RATS

2010 ◽  
Vol 23 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Rainer H. Böger ◽  
Stefanie M. Bode-Böger ◽  
Uwe Gerecke ◽  
Frank-M Gutzki ◽  
Dimitrios Tsikas ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Oral Administration ◽  
Oxide Formation ◽  
Nitric Oxide Formation

Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction

Diabetes ◽  
1992 ◽  
Vol 41 (4) ◽  
pp. 552-556 ◽  
Author(s):  
J. A. Corbett ◽  
R. G. Tilton ◽  
K. Chang ◽  
K. S. Hasan ◽  
Y. Ido ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Vascular Dysfunction ◽  
Oxide Formation ◽  
Nitric Oxide Formation
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