scholarly journals Comment on Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK

2006 ◽  
Vol 58 (1) ◽  
pp. 220-220 ◽  
Author(s):  
L. Leibovici
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
The Uk

Methicillin-resistant Staphylococcus aureus in the UK and Ireland. A questionnaire survey

1986 ◽  
Vol 8 (2) ◽  
pp. 143-148 ◽  
Author(s):  
E.M. Cooke ◽  
M.W. Casewell ◽  
A.M. Emmerson ◽  
M. Gaston ◽  
M. de Saxe ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Questionnaire Survey ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
The Uk

scholarly journals Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK

2006 ◽  
Vol 57 (4) ◽  
pp. 589-608 ◽  
Author(s):  
Curtis G. Gemmell ◽  
David I. Edwards ◽  
Adam P. Fraise ◽  
F. Kate Gould ◽  
Geoff L. Ridgway ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
The Uk

scholarly journals Decline of EMRSA-16 amongst methicillin-resistant Staphylococcus aureus causing bacteraemias in the UK between 2001 and 2007

2009 ◽  
Vol 65 (3) ◽  
pp. 446-448 ◽  
Author(s):  
M. J. Ellington ◽  
R. Hope ◽  
D. M. Livermore ◽  
A. M. Kearns ◽  
K. Henderson ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
The Uk

scholarly journals Livestock-Associated Methicillin-Resistant Staphylococcus aureus From Animals and Animal Products in the UK

2019 ◽  
Vol 10 ◽  
Author(s):  
Muna F. Anjum ◽  
Francisco Marco-Jimenez ◽  
Daisy Duncan ◽  
Clara Marín ◽  
Richard P. Smith ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Animal Products ◽  
Methicillin Resistant ◽  
The Uk

scholarly journals Reductions in Methicillin-resistant Staphylococcus aureus, Clostridium difficile Infection and Intensive Care Unit–Acquired Bloodstream Infection Across the United Kingdom Following Implementation of a National Infection Control Campaign

2019 ◽  
Vol 70 (12) ◽  
pp. 2530-2540 ◽  
Author(s):  
Jonathan D Edgeworth ◽  
Rahul Batra ◽  
Jerome Wulff ◽  
David Harrison
Keyword(s):  
Intensive Care Unit ◽  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Infection Control ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Candida Spp ◽  
Methicillin Resistant ◽  
The Uk ◽  
Control Campaign

Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections declined across the UK National Health Service in the decade that followed implementation of an infection control campaign. The national impact on intensive care unit (ICU)-acquired infections has not been documented. Methods Data on MRSA, C. difficile, vancomycin-resistant Enterococcus (VRE), and ICU–acquired bloodstream infections (UABSIs) for 1 189 142 patients from 2007 to 2016 were analyzed. Initial coverage was 139 ICUs increasing to 276 ICUs, representing 100% of general adult UK ICUs. Results ICU MRSA and C. difficile acquisitions per 1000 patients decreased between 2007 and 2016 (MRSA acquisitions, 25.4 to 4.1; and C. difficile acquisitions, 11.1 to 3.5), whereas VRE acquisitions increased from 1.5 to 5.9. There were 13 114 UABSIs in 1.8% of patients who stayed longer than 48 hours on ICU. UABSIs fell from 7.3 (95% confidence interval [CI], 6.9–7.6) to 1.6 (95% CI, 1.5–1.7)/1000 bed days. Adjusting for patient factors, the incidence rate ratio was 0.21 (95% CI, 0.19–0.23, P < .001) from 2007 to 2016. The greatest reduction, comparing rates in 2007/08 and 2015/16, was for MRSA (97%), followed by P. aeruginosa (81%), S. aureus (79%) and Candida spp (72%), with lower reductions for the coliforms (E. coli 57% and Klebsiella 49%). Conclusions Large decreases in ICU-acquired infections occurred across the UK ICU network linked with the first few years of a national infection control campaign, but rates have since been static. Further reductions will likely require a new intervention framework.

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