scholarly journals Evaluation of the in vitro activity of NVP-LMB415 against clinical anaerobic isolates with emphasis on the Bacteroides fragilis group

2005 ◽  
Vol 55 (6) ◽  
pp. 1024-1028 ◽  
Author(s):  
David R. Snydman ◽  
Nilda V. Jacobus ◽  
Laura A. McDermott
2020 ◽  
Vol 64 (9) ◽  
Author(s):  
Ellie J. C. Goldstein ◽  
C. Vreni Merriam ◽  
Diane M. Citron

ABSTRACT Tedizolid’s anaerobic activity is unappreciated. In this study, it was active against all 332 anaerobic isolates tested at ≤2 μg/ml except Bilophila wadsworthia and was more active than linezolid against Bacteroides fragilis group species (MIC90, 1 μg/ml versus 2 to 4 μg/ml). Tedizolid was active against Gram-positive anaerobes (MIC90 for clostridia, 0.25 to 1 μg/ml; MIC90 for anaerobic cocci, ≤0.06 to 0.25 μg/ml). Our data coupled with clinical reports indicate that clinicians should consider its use in mixed infections where Staphylococcus aureus and anaerobes are involved.


1991 ◽  
Vol 27 (5) ◽  
pp. 599-606 ◽  
Author(s):  
J. A. García-Rodriguez ◽  
J. E. García Sánchez ◽  
I. Trujillano ◽  
A. Sánchez de San Lorenzo

Infection ◽  
1991 ◽  
Vol 19 (5) ◽  
pp. 377-379 ◽  
Author(s):  
H. Werner ◽  
W. R. Heizmann ◽  
M. Höflsauer

Anaerobe ◽  
2017 ◽  
Vol 43 ◽  
pp. 1-3 ◽  
Author(s):  
Ellie J.C. Goldstein ◽  
Diane M. Citron ◽  
Kerin L. Tyrrell ◽  
Elisa S. Leoncio ◽  
C. Vreni Merriam

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