scholarly journals Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites

2002 ◽  
Vol 50 (3) ◽  
pp. 411-420 ◽  
Author(s):  
E. J. C. Goldstein
1998 ◽  
Vol 42 (4) ◽  
pp. 984-986 ◽  
Author(s):  
Hannah M. Wexler ◽  
Eric Molitoris ◽  
Denise Molitoris ◽  
Sydney M. Finegold

ABSTRACT The in vitro activity of levofloxacin was compared to the activities of ofloxacin, ciprofloxacin, ampicillin-sulbactam (2:1), cefoxitin, and metronidazole for a selected group of anaerobes (n = 175) isolated from skin and soft tissue infections by using the National Committee for Clinical Laboratory Standards-approved Wadsworth method. Ampicillin-sulbactam and cefoxitin inhibited 99% of the strains of this select group, levofloxacin and ofloxacin inhibited 73 and 50%, respectively, at 2 μg/ml, and ciprofloxacin inhibited 51% at 1 μg/ml. The geometric mean MIC of levofloxacin was lower than those of ofloxacin and ciprofloxacin for every group except Veillonella.


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