scholarly journals In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans

2000 ◽  
Vol 45 (2) ◽  
pp. 231-233 ◽  
Author(s):  
H. S. Thangaraj ◽  
O. Adjei ◽  
B. W. Allen ◽  
F. Portaels ◽  
M. R. W. Evans ◽  
...  
Keyword(s):  
Mycobacterium Ulcerans ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In Vitro Activity of Selected West African Medicinal Plants against Mycobacterium ulcerans Disease

Molecules ◽  
2016 ◽  
Vol 21 (4) ◽  
pp. 445 ◽  
Author(s):  
Patrick Tsouh Fokou ◽  
Abena Kissi-Twum ◽  
Dorothy Yeboah-Manu ◽  
Regina Appiah-Opong ◽  
Phyllis Addo ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
West African ◽  
Mycobacterium Ulcerans ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In-vitro Activity of Avermectins against Mycobacterium ulcerans

2015 ◽  
Vol 9 (3) ◽  
pp. e0003549 ◽  
Author(s):  
Till F. Omansen ◽  
Jessica L. Porter ◽  
Paul D. R. Johnson ◽  
Tjip S. van der Werf ◽  
Ymkje Stienstra ◽  
...  
Keyword(s):  
Mycobacterium Ulcerans ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In vitro activity of SPR719 against Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera

2021 ◽  
Vol 15 (7) ◽  
pp. e0009636
Author(s):  
Sacha J. Pidot ◽  
Jessica L. Porter ◽  
Troy Lister ◽  
Timothy P. Stinear
Keyword(s):  
Clinical Stage ◽  
Treatment Options ◽  
Active Form ◽  
Mycobacterium Marinum ◽  
Mycobacterium Ulcerans ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
The World

Nontuberculosis mycobacterial (NTM) infections are increasing in prevalence across the world. In many cases, treatment options for these infections are limited. However, there has been progress in recent years in the development of new antimycobacterial drugs. Here, we investigate the in vitro activity of SPR719, a novel aminobenzimidazole antibiotic and the active form of the clinical-stage compound, SPR720, against several isolates of Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera. We show that SPR719 is active against these NTM species with a MIC range of 0.125–4 μg/ml and that this compares favorably with the commonly utilized antimycobacterial antibiotics, rifampicin and clarithromycin. Our findings suggest that SPR720 should be further evaluated for the treatment of NTM infections.

In Vitro Activity of Phytocannabinoids from High Potency Cannabis sativa

Planta Medica ◽  
2012 ◽  
Vol 78 (05) ◽  
Author(s):  
A Husni ◽  
S Ross ◽  
O Dale ◽  
C Gemelli ◽  
G Ma ◽  
...  
Keyword(s):  
Cannabis Sativa ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
High Potency
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