scholarly journals Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines

2002 ◽  
Vol 14 (7) ◽  
pp. 751-760 ◽  
Author(s):  
A. A. Kulidjian
Keyword(s):  
T Lymphocyte ◽  
Lymphocyte Migration ◽  
Inflammatory Reactions

Characterizing the role of integrin alpha8 in mediating CD4+ T lymphocyte migration across the blood–brain barrier in multiple sclerosis

2014 ◽  
Vol 275 (1-2) ◽  
pp. 99-100
Author(s):  
Elizabeth Gowing ◽  
Steve Gendron ◽  
Marc-andré Lécuyer ◽  
Simone Terouz ◽  
Alexandre Prat
Keyword(s):  
Multiple Sclerosis ◽  
Blood Brain Barrier ◽  
T Lymphocyte ◽  
Brain Barrier ◽  
Lymphocyte Migration ◽  
Blood Brain

scholarly journals Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration

2013 ◽  
Vol 7 (1) ◽  
pp. 38-43 ◽  
Author(s):  
Pascale Giraudon ◽  
Adeline Nicolle ◽  
Sylvie Cavagna ◽  
Claire Benetollo ◽  
Romain Marignier ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Lymphocyte Migration ◽  
Collapsin Response Mediator Protein ◽  
Mediator Protein ◽  
Insight Into

scholarly journals Role of Regulator of G Protein Signaling 16 in Inflammation- Induced T Lymphocyte Migration and Activation

2003 ◽  
Vol 171 (3) ◽  
pp. 1542-1555 ◽  
Author(s):  
Eric Lippert ◽  
David L. Yowe ◽  
Jose-Angel Gonzalo ◽  
J. Paul Justice ◽  
Jeremy M. Webster ◽  
...  
Keyword(s):  
G Protein ◽  
T Lymphocyte ◽  
G Protein Signaling ◽  
Protein Signaling ◽  
Lymphocyte Migration

The Pathophysiology of Asthma

1997 ◽  
Vol 10 (3) ◽  
pp. 176-185
Author(s):  
Thomas G. Vondracek ◽  
Walter F. Stanaszek
Keyword(s):  
Airway Inflammation ◽  
T Lymphocyte ◽  
Inflammatory Cells ◽  
Predisposing Factor ◽  
Inflammatory Reactions ◽  
Acute Exacerbations ◽  
Infiltrating Cells ◽  
Mucosal Edema ◽  
Ige Mediated

Atopy predisposes an individual to the development of asthma, whereby specific triggers may repeatedly cause acute exacerbations and contribute to chronic inflammation. This IgE-mediated response to common allergens is the strongest predisposing factor for developing asthma. Airway inflammation involves release of immunological mediators via T lymphocyte dependent, and IgE dependent and independent mechanisms which attract inflammatory cells from the circulation. The role of the eicosanoids as pivotal mediators in promoting some of the changes in asthma has only recently been fully explored. Inflammatory reactions result when mediators and cytokines released from resident and infiltrating cells interact. This interaction also contributes to the bronchoconstriction, hypersecretion, and mucosal edema in the airways.

The role of the integrin LFA-1 in T-lymphocyte migration

2007 ◽  
Vol 218 (1) ◽  
pp. 135-146 ◽  
Author(s):  
Andrew Smith ◽  
Paula Stanley ◽  
Kristian Jones ◽  
Lena Svensson ◽  
Alison McDowall ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Lymphocyte Migration

Recent Advances in Obesity: The Role of Turmeric Tuber and Its Metabolites in the Prophylaxis and Therapeutical Strategies

2019 ◽  
Vol 25 (37) ◽  
pp. 4837-4853 ◽  
Author(s):  
Agata Jarząb ◽  
Wirginia Kukula-Koch
Keyword(s):  
Body Weight ◽  
21St Century ◽  
The Body ◽  
Excess Body Weight ◽  
Inflammatory Reactions ◽  
Drug Candidates ◽  
Scientific Papers ◽  
Important Health ◽  
High Concern

Background: Obesity in the 21st century society became an important health problem, alarming both the scientists and medicine doctors around the world. That is why, the search for new drug candidates capable to reduce the body weight is of high concern. Objective: This contribution tends to collect current findings on the biochemistry of obesity and on the application of plants and in particular turmeric tuber – a commonly used spice - as an anti-obesity agent. Methods: Following an introduction on the biochemical characteristics of obesity, the description of Curcuma secondary metabolites, their pharmacological applications and a study on the plants’ regulatory properties in obesity was summarized. Particular attention was paid to curcumin – the major metabolite present in the extracts of Curcuma spp., which is known to exhibit a variety of pharmacological actions. Also, the characteristics of some semisynthetic analogues of this ferulic acid derivative, characterized by a higher polarity and better bioavailability will be discussed. Results: Numerous scientific papers treat on the influence of turmeric on weight loss. Additionally, some of them describe its anti-inflammatory properties. Conclusions: This important spice tends to fight the 21st century plague, which is an excessive weight gain, related to the development of metabolic syndrome, to the occurrence of cardiovascular problems and diabetes, and, in consequence, leading to a significant shortening of life span. As herein proven, the extracts of turmeric play an important role in the regulation of inflammatory reactions which are evoked in the overweight patients, helping them reduce the excess body weight.

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