scholarly journals Optimization of Clonazepam Therapy Adjusted to Patient’s CYP3A Status andNAT2Genotype

2016 ◽  
Vol 19 (12) ◽  
pp. pyw083 ◽  
Author(s):  
Katalin Tóth ◽  
Gábor Csukly ◽  
Dávid Sirok ◽  
Ales Belic ◽  
Ádám Kiss ◽  
...  
Keyword(s):  
Clonazepam Therapy

Psychosis associated with clonazepam therapy for blepharospasm

1982 ◽  
Vol 2 (4) ◽  
pp. 294
Author(s):  
Michael C. White ◽  
Joel J. Silverman ◽  
John W. Harbison
Keyword(s):  
Clonazepam Therapy

scholarly journals Plasma Concentrations of Clonazepam Therapy in Epileptic Children.

1997 ◽  
Vol 23 (1) ◽  
pp. 36-42
Author(s):  
NORIFUMI MORIKAWA ◽  
KAZURO IKAWA ◽  
TATURO IZUMI ◽  
MASAHARU TAKEYAMA
Keyword(s):  
Plasma Concentrations ◽  
Epileptic Children ◽  
Clonazepam Therapy

Psychosis Associated with Clonazepam Therapy for Blepharospasm

1982 ◽  
Vol 170 (2) ◽  
pp. 117-119 ◽  
Author(s):  
MICHAEL C. WHITE ◽  
JOEL J. SILVERMAN ◽  
JOHN W. HARBISON
Keyword(s):  
Clonazepam Therapy

scholarly journals Prediction of treatment outcome in burning mouth syndrome patients using machine learning based on clinical data

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Moon-Jong Kim ◽  
Pil-Jong Kim ◽  
Hong-Gee Kim ◽  
Hong-Seop Kho
Keyword(s):  
Machine Learning ◽  
Treatment Outcomes ◽  
Clinical Data ◽  
Prediction Models ◽  
Burning Mouth Syndrome ◽  
Learning Approach ◽  
Initial Approach ◽  
Machine Learning Approach ◽  
Burning Mouth ◽  
Clonazepam Therapy

AbstractThe purpose of this study is to apply a machine learning approach to predict whether patients with burning mouth syndrome (BMS) respond to the initial approach and clonazepam therapy based on clinical data. Among the patients with the primary type of BMS who visited the clinic from 2006 to 2015, those treated with the initial approach of detailed explanation regarding home care instruction and use of oral topical lubricants, or who were prescribed clonazepam for a minimum of 1 month were included in this study. The clinical data and treatment outcomes were collected from medical records. Extreme Gradient-Boosted Decision Trees was used for machine learning algorithms to construct prediction models. Accuracy of the prediction models was evaluated and feature importance calculated. The accuracy of the prediction models for the initial approach and clonazepam therapy was 67.6% and 67.4%, respectively. Aggravating factors and psychological distress were important features in the prediction model for the initial approach, and intensity of symptoms before administration was the important feature in the prediction model for clonazepam therapy. In conclusion, the analysis of treatment outcomes in patients with BMS using a machine learning approach showed meaningful results of clinical applicability.

Clonazepam therapy in reading epilepsy

Neurology ◽  
1983 ◽  
Vol 33 (1) ◽  
pp. 117-117 ◽  
Author(s):  
P. Watson
Keyword(s):  
Clonazepam Therapy

Clonazepam therapy in reading epilepsy

Neurology ◽  
1981 ◽  
Vol 31 (1) ◽  
pp. 115-115 ◽  
Author(s):  
I. S. LOGIN
Keyword(s):  
Clonazepam Therapy

High-Dose Lorazepam Therapy for Status Epilepticus in a Pediatric Patient

1988 ◽  
Vol 22 (11) ◽  
pp. 889-890 ◽  
Author(s):  
Hanna M. Reincke ◽  
Robin L. Gilmore ◽  
Robert J. Kuhn
Keyword(s):  
Status Epilepticus ◽  
Total Dose ◽  
Respiratory Depression ◽  
Pediatric Patient ◽  
Benzodiazepine Receptor ◽  
High Dose ◽  
Potential Complication ◽  
Down Regulation ◽  
Clonazepam Therapy ◽  
High Total Dose

This report details the management of status epilepticus with high-dose lorazepam in a 14-year-old patient who was receiving oral clonazepam, ethosuximide, and phenobarbital for an intractable seizure disorder. Although respiratory depression is a frequently cited potential complication of therapy, it did not occur in this patient despite an extraordinarily high total dose of lorazepam, possibly because of tolerance associated with benzodiazepine-receptor down-regulation in this patient's chronic clonazepam therapy. Aggressive dosing of a benzodiazepine may be required for patients receiving chronic benzodiazepine therapy.

Buspirone and Sertraline in the Treatment of a Patient with Refractory Obsessive-Compulsive Disorder

1995 ◽  
Vol 11 (2) ◽  
pp. 50-52 ◽  
Author(s):  
Amy J. Veivia ◽  
Gary M. Levin ◽  
Hannah S. Powell
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Subjective Improvement ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Symptoms Of Depression ◽  
Case Summary ◽  
Clonazepam Therapy

Objective: To describe a hospitalized patient with refractory obsessive-compulsive disorder (OCD) and to briefly review the supporting literature. Case Summary: A 33-year-old man was admitted with a diagnosis of depression and OCD. Prior drug therapy included numerous medications, but none improved the OCD. Clonazepam therapy was initiated for treatment of anxiety and propranolol was begun to treat his headaches. Sertraline and buspirone were added sequentially to control the symptoms of depression and OCD. Subjective improvement was noted within a few weeks after the combination therapy was begun. Six and four weeks after starting sertraline and buspirone, respectively, the patient's symptoms remain improved. Discussion: Fluoxetine has been shown to be effective in the management of OCD. Sertraline, another selective serotonin-reuptake inhibitor, also looks promising for OCD therapy. Buspirone is a serotonin1A-receptor agonist, and theoretically could augment the effect of selective serotonin-reuptake inhibitors in the treatment of OCD. Conclusions: This patient's OCD symptoms responded to a combination of sertraline and buspirone therapy. It is difficult to confirm whether buspirone augmented the effects of sertraline in this patient. Clinical trials should be developed to determine whether these regimens are, in fact, beneficial in patients with refractory OCD.

The Long-Term Effectiveness of Clonazepam Therapy in the Control of Partial Seizures in Children Difficult to Control with Carbamazepine Monotherapy

1991 ◽  
Vol 45 (2) ◽  
pp. 471-473 ◽  
Author(s):  
Nozomi Hosoda ◽  
Hisao Miura ◽  
Sakae Takanashi ◽  
Hiroyuki Shirai ◽  
Wataru Sunaoshi
Keyword(s):  
Partial Seizures ◽  
Clonazepam Therapy
Sign in / Sign up

Export Citation Format

Share Document