scholarly journals Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children

2015 ◽  
Vol 44 (4) ◽  
pp. 1288-1304 ◽  
Author(s):  
Gemma C Sharp ◽  
Debbie A Lawlor ◽  
Rebecca C Richmond ◽  
Abigail Fraser ◽  
Andrew Simpkin ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Weight Gain ◽  
Longitudinal Study ◽  
Gestational Weight Gain ◽  
Gestational Weight ◽  
Parents And Children ◽  
Avon Longitudinal Study ◽  
Offspring Adiposity

scholarly journals Associations of maternal diet and nutritional status with offspring hepatic steatosis in the Avon longitudinal study of parents and children

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ahlia Sekkarie ◽  
Jean A. Welsh ◽  
Kate Northstone ◽  
Aryeh D. Stein ◽  
Usha Ramakrishnan ◽  
...  
Keyword(s):  
Weight Gain ◽  
Longitudinal Study ◽  
Nutritional Status ◽  
Hepatic Steatosis ◽  
Free Sugar ◽  
Sugar Intake ◽  
Maternal Nutritional Status ◽  
Gestational Weight ◽  
Parents And Children ◽  
Avon Longitudinal Study

Abstract Background Priming for cardiometabolic diseases, including non-alcoholic fatty liver disease (NAFLD), is hypothesized to begin in utero. The primary objective of this study is to determine whether there is an association between maternal nutritional status and offspring NAFLD. Methods Data come from the Avon Longitudinal Study of Parents and Children (ALSPAC) in the UK. The analytic sample included 3353 participants who had maternal information on pre-pregnancy BMI, gestational weight gain, diabetes, and free sugar intake as percent of total energy and were assessed for mild-severe hepatic steatosis at 24 years by transient elastography (controlled attenuation parameter score ≥ 248 dB/m). Multiple logistic regression was used to evaluate the association between maternal factors and offspring hepatic steatosis at 24 years. Results In confounder-adjusted models the independent associations for each maternal factor with mild to severe vs low hepatic steatosis at 24 years were: pre-pregnancy overweight (OR: 1.84, 95%CL: 1.43–2.38) or obesity (OR: 2.73, 95%CL: 1.84–4.03), more than recommended gestational weight gain (OR: 1.30, 95%CL: 1.04–1.64), diabetes (OR: 1.39, 95%CI: 0.87, 2.21), and high free sugar intake during pregnancy (OR: 1.04, 95% CI: 0.82, 1.33). These associations were largely mediated by BMI at 24 years, but not by birthweight or breastfeeding. Conclusions Our results suggest that maternal nutritional status is associated with the development of NAFLD in their adult offspring, although the relationship is largely mediated by offspring BMI in adulthood.

scholarly journals Association between gestational weight gain and risk of obesity in preadolescence: a longitudinal study (1997-2007) of 5125 children in Greece

2016 ◽  
Vol 30 (1) ◽  
pp. 51-58 ◽  
Author(s):  
S. P. Mourtakos ◽  
K. D. Tambalis ◽  
D. B. Panagiotakos ◽  
G. Antonogeorgos ◽  
C. D. Alexi ◽  
...  
Keyword(s):  
Weight Gain ◽  
Longitudinal Study ◽  
Gestational Weight Gain ◽  
Gestational Weight

scholarly journals Antenatal dietary concordance among mothers and fathers and gestational weight gain: a longitudinal study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Roger Figueroa ◽  
Jaclyn A. Saltzman ◽  
Augustine Kang ◽  
Fernanda Neri Mini ◽  
Kirsten K. Davison ◽  
...  
Keyword(s):  
Weight Gain ◽  
Longitudinal Study ◽  
Gestational Weight Gain ◽  
Mothers And Fathers ◽  
Gestational Weight

A longitudinal study on the relationship between eating style and gestational weight gain

Appetite ◽  
2014 ◽  
Vol 83 ◽  
pp. 304-308 ◽  
Author(s):  
Carla L. van der Wijden ◽  
Stefanie Steinbach ◽  
Hidde P. van der Ploeg ◽  
Willem van Mechelen ◽  
Mireille N.M. van Poppel
Keyword(s):  
Weight Gain ◽  
Longitudinal Study ◽  
Gestational Weight Gain ◽  
Eating Style ◽  
Gestational Weight ◽  
The Relationship

scholarly journals DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort

2014 ◽  
Vol 7 (1) ◽  
pp. 278 ◽  
Author(s):  
Eva Morales ◽  
Alexandra Groom ◽  
Debbie A Lawlor ◽  
Caroline L Relton
Keyword(s):  
Dna Methylation ◽  
Weight Gain ◽  
Cord Blood ◽  
Gestational Weight Gain ◽  
Gestational Weight
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