scholarly journals Creating Females? Developmental Effects of 17 -Ethynylestradiol on the Mangrove Rivulus' Ovotestis

2012 ◽  
Vol 52 (6) ◽  
pp. 769-780 ◽  
Author(s):  
J. L. Farmer ◽  
E. F. Orlando
Keyword(s):  
Developmental Effects ◽  
Mangrove Rivulus

Developmental Effects of Poverty on Part C Recipients

2006 ◽  
Author(s):  
Elizabeth H. Snyder ◽  
Anita A. Scarborough ◽  
Kathleen M. Hebbel ◽  
Erdonna M. Spiker
Keyword(s):  
Part C ◽  
Developmental Effects

Developmental Effects Associated with Exposure to Xylene: A Review

1985 ◽  
Vol 8 (4) ◽  
pp. 281-297 ◽  
Author(s):  
Ronald D. Hood ◽  
Myron S. Ottley
Keyword(s):  
Developmental Effects

Teratogenic Potential of FD&C RED NO. 3 When given by Gavage

1993 ◽  
Vol 9 (4) ◽  
pp. 605-616 ◽  
Author(s):  
T.F.X. Collins ◽  
T.N. Black ◽  
D.I. Ruggles
Keyword(s):  
Clinical Findings ◽  
Feed Consumption ◽  
Maternal Weight ◽  
Entire Treatment Period ◽  
Developmental Effects ◽  
Random Occurrence ◽  
Teratogenic Potential ◽  
Fetal Size ◽  
Dose Levels ◽  
Entire Treatment

FD&C Red No. 3 (erythrosine) is a commonly used food additive. As part of a series of studies on the potential fetal developmental effects of food colors, FD&C Red No. 3 was administered by gavage to pregnant Osborne-Mendel rats at daily dose levels of 15, 30, 100, 200, 400, or 800 mg/kg on days 0-19 of gestation. Control animals were given distilled water by gavage. On gestation day 20, the animals were euthanized and cesarean sections were performed. During the entire treatment period, feed consumption by the animals given 400 mg/kg doses was increased significantly; the increases in the animals given 30 or 800 mg/kg were of borderline significance. The only significant increase in maternal weight gain, on days 0-7 in the animals given 30 mg/kg, was considered a random occurrence. No dose-related changes were seen in maternal clinical findings, implantations, fetal viability, or fetal size (weight and length). No fetal terata were seen, and neither skeletal nor visceral development was affected. FD&C Red No. 3 was neither fetotoxic nor teratogenic at 800 mg/kg when given by gavage.

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