P115 RELATIONS BETWEEN DISEASE STATUS AND BODY COMPOSITION IN PEDIATRIC INFLAMMATORY BOWEL DISEASE

2020 ◽  
Vol 26 (Supplement_1) ◽  
pp. S18-S19
Author(s):  
Saurabh Talathi ◽  
Pooja Nagaraj ◽  
Traci Jester ◽  
Jeanine Maclin ◽  
Taylor Knight ◽  
...  
Keyword(s):  
Physical Activity ◽  
Inflammatory Bowel Disease ◽  
Body Composition ◽  
Bowel Disease ◽  
Active Group ◽  
Lower Percentage ◽  
Physician Global Assessment ◽  
Healthy Controls ◽  
Mineral Density ◽  
Inflammatory Bowel

Abstract Objective To evaluate the effect of remission status on physical activity, and body composition in pediatric patients with inflammatory bowel disease (PIBD) and healthy peers. Methods Single center cohort study including 54 PIBD patients and 33 healthy peers. During initial study visit, a brief demographic questionnaire, physical activity questionnaire completed by participants and instructions on recording dietary intake were given. Physicians completed the Physician Global Assessment (PGA) for disease severity. Medical chart abstraction done to obtain disease variables of interest. DEXA scan completed one week later to obtain information on body composition. Variables of interest were compared between the three groups (IBD-Remission, IBD-Active and healthy controls) using an ANOVA or Chi square test as appropriate. Results IBD patients were older than controls, reported lower quality of life (73.9 vs 80.9) and engaged in less MVPA (195.4 versus 361.1). IBD-Active group had a significantly lower lean body mass, bone mineral density and time spent in MVPA compared to IBD-Remission group and healthy controls. IBD-Remission group had a significantly lower percentage of biologic use (55% vs 87%) and comorbidities (26% vs 44%) compared to IBD-active group. IBD-remission group also had a lower fat mass percentage. Discussion In this study, we report significantly favorable LBM, BMD, and time spent in MVPA in patients with IBD in remission compared to those not in remission with the former demonstrating a body composition resembling to that of healthy peers. While an improvement in BMD was observed with remission, the scores were still lower than controls.

scholarly journals Bone Mineral Density and Bone Remodeling in Tunisian Patients with Inflammatory Bowel Disease

2019 ◽  
Vol 13 (1) ◽  
pp. 22-29
Author(s):  
Samar Ben Jemaa ◽  
Lassaad Chtourou ◽  
Rim Akrout ◽  
Khansa Chaabouni ◽  
Tarek Chaabouni ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Remodeling ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Healthy Controls ◽  
Mineral Density ◽  
High Prevalence ◽  
Inflammatory Bowel

Background:A high prevalence of osteopenia and osteoporosis is observed in patients with Inflammatory Bowel Disease (IBD).Objective:The aim of our study was to investigate the prevalence of bone loss, bone remodeling and risk factors in Tunisian patient with IBD.Patients and Methods:The study included 40 patients with IBD and 32 age- and sex-matched healthy controls subjects. All participants underwent bone densitometry by dual energy X-ray absorptiometry at the femoral neck and lumbar spine. Serum levels of 25-hydroxy vitamin D (25(OH)D), parathyroid hormone (PTH), osteocalcin(OC), and urinary degradation products of C-terminal telopeptide of type I collagen (CTXI) were measured in all participants to assess the bone metabolism status.Results:Twelve (30%) patients were normal, 32.5% were osteopenic and 37.5% were osteoporotic. Osteoporosis was more frequent in IBD patients than controls (p=0.0001). Age and inflammation were associated with low bone mineral density (BMD). Mean calcium, phosphorus and alkaline phosphatase levels were similar in both groups. Median 25(OH) D levels were significantly lower in IBD patients compared with controls (p=0.0001). Median urinary CTXI levels were significantly higher in IBD patients compared with healthy controls (p=0.007). No significant differences between IBD patients and controls concerning the median serum OC and PTH levels were found.Conclusion:In our study, there is a high prevalence of low BMD in IBD patients and an increase in bone resorption without a change of bone formation. Low BMI and hypovitaminoses D were identified as risk factors for low BMD.

Fatigue, Physical Activity, and Mental Health in People Living With Inflammatory Bowel Disease, Fibromyalgia, and in Healthy Controls

2020 ◽  
Vol 43 (2) ◽  
pp. 172-185
Author(s):  
Lisa S. Olive ◽  
Catherine A. Emerson ◽  
Eliza Cooper ◽  
Emily M. Rosenbrock ◽  
Antonina A. Mikocka-Walus
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Healthy Controls ◽  
Inflammatory Bowel

scholarly journals Associations of Lifestyle Factors with Osteopenia and Osteoporosis in Polish Patients with Inflammatory Bowel Disease

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1863
Author(s):  
Anna Maria Rychter ◽  
Alicja Ewa Ratajczak ◽  
Aleksandra Szymczak-Tomczak ◽  
Michał Michalak ◽  
Piotr Eder ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Inflammatory Bowel Disease ◽  
Alcohol Consumption ◽  
Bowel Disease ◽  
Study Group ◽  
Mineral Density ◽  
Reduced Physical Activity ◽  
Inflammatory Bowel ◽  
Made In

Reduced physical activity (PA), smoking, and coffee and alcohol drinking constitute risk factors of osteoporosis in patients with inflammatory bowel disease (IBD). The aim of the study was to measure the bone mineral density (BMD) and frequency of osteopenia and osteoporosis in patients with IBD and their correlation with PA, smoking, coffee, and alcohol. The study group consisted of 208 patients with IBD-103 with Crohn’s disease (CD), 105 suffering from ulcerative colitis (UC). Densitometric measurements were performed using the DXA. All patients completed a questionnaire concerning PA, smoking, and coffee and alcohol consumption. The prevalence of osteopenia and osteoporosis (L2–L4) in the IBD group was 48.1%; in the CD group, it amounted to 48.6%, and in the UC group, the prevalence was equal to 33.3%. Patients with CD who were diagnosed with osteopenia and osteoporosis demonstrated reduced PA compared to patients with a normal BMD who exercised regularly (p = 0.0335). A similar observation was made in the group of women with IBD. Women with a normal BMD exercised significantly more often than women suffering from osteopenia and osteoporosis (p = 0.0146). However, no differences in BMD were observed with regard to coffee use, alcohol consumption, or smoking. Thus, since the incidence of osteoporosis in IBD patients is high, it may be dependent on PA.

scholarly journals Lean body mass, physical activity and quality of life in paediatric patients with inflammatory bowel disease and in healthy controls

2012 ◽  
Vol 6 (6) ◽  
pp. 665-673 ◽  
Author(s):  
Katharina J. Werkstetter ◽  
Jennifer Ullrich ◽  
Stephanie B. Schatz ◽  
Christine Prell ◽  
Berthold Koletzko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Inflammatory Bowel Disease ◽  
Lean Body Mass ◽  
Body Mass ◽  
Bowel Disease ◽  
Healthy Controls ◽  
Paediatric Patients ◽  
Inflammatory Bowel
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