The Prevalence and Risk Factors of Undiagnosed Depression and Anxiety Disorders Among Patients With Inflammatory Bowel Disease

2019 ◽  
Vol 25 (10) ◽  
pp. 1674-1680 ◽  
Author(s):  
Kylee Lewis ◽  
Ruth Ann Marrie ◽  
Charles N Bernstein ◽  
Lesley A Graff ◽  
Scott B Patten ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Anxiety Disorders ◽  
Bowel Disease ◽  
Significant Proportion ◽  
Depression And Anxiety ◽  
Immune Mediated ◽  
Lower Education Level ◽  
High Prevalence ◽  
Inflammatory Bowel ◽  
Axis I

Abstract Background Inflammatory bowel disease (IBD) is associated with a high prevalence of comorbid depressive and anxiety disorders. A significant proportion of IBD patients with comorbid psychiatric disorders remain undiagnosed and untreated, but factors associated with diagnosis are unknown. We evaluated the prevalence of undiagnosed depression and anxiety in an IBD cohort, along with the associated demographic and clinical characteristics. Methods We obtained data from the enrollment visit of a cohort study of psychiatric comorbidity in immune-mediated diseases including IBD. Each participant underwent a Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID) to identify participants who met lifetime criteria for a diagnosis of depression or anxiety. Those with a SCID-based diagnosis were classified as diagnosed or undiagnosed based on participant report of a physician diagnosis. Results Of 242 eligible participants, 97 (40.1%) met SCID criteria for depression, and 74 (30.6%) met criteria for anxiety. One-third of participants with depression and two-thirds with anxiety were undiagnosed. Males were more likely to have an undiagnosed depressive disorder (odds ratio [OR], 3.36; 95% confidence interval [CI], 1.28–8.85). Nonwhite participants were less likely to have an undiagnosed anxiety disorder (OR, 0.17; 95% CI, 0.042–0.72). Conclusion Our findings highlight the importance of screening for depression and anxiety in patients with IBD, with particular attention to those of male sex and with a lower education level.

scholarly journals Prevalence of Anxiety and Depression in Patients with Inflammatory Bowel Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Glynis Byrne ◽  
Greg Rosenfeld ◽  
Yvette Leung ◽  
Hong Qian ◽  
Julia Raudzus ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Multivariable Analysis ◽  
Significant Proportion ◽  
Mental Illnesses ◽  
Self Report ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Psychiatric Interview ◽  
Inflammatory Bowel

Background. Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life. Methods. Prevalence of anxiety and depression was assessed in IBD outpatients through retrospective chart review. The presence of anxiety and/or depression was determined using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 self-report questionnaires or by diagnosis through psychiatric interview. Patient demographics, disease characteristics, and medication information were also collected. Multivariable analysis was used to determine associations between patient factors and depression and anxiety. Results. 327 patient charts were reviewed. Rates of depression and anxiety were found to be 25.8% and 21.2%, with 30.3% of patients suffering from depression and/or anxiety. Disease activity was found to be significantly associated with depression and/or anxiety (p=0.01). Females were more likely to have anxiety (p=0.01). Conclusion. A significant proportion of IBD patients suffer from depression and/or anxiety. The rates of these mental illnesses would justify screening and referral for psychiatric treatment in clinics treating this population. Patients with active disease are particularly at risk for anxiety and depression.

scholarly journals The Validity and Reliability of Screening Measures for Depression and Anxiety Disorders in Inflammatory Bowel Disease

2018 ◽  
Vol 24 (9) ◽  
pp. 1867-1875 ◽  
Author(s):  
Charles N Bernstein ◽  
Lixia Zhang ◽  
Lisa M Lix ◽  
Lesley A Graff ◽  
John R Walker ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Anxiety Disorders ◽  
Bowel Disease ◽  
Depression And Anxiety ◽  
Validity And Reliability ◽  
Inflammatory Bowel ◽  
Screening Measures

P210 Depression and anxiety disorders impact in the quality of life of patients with inflammatory bowel disease

2019 ◽  
Vol 13 (Supplement_1) ◽  
pp. S198-S200
Author(s):  
J Yamamoto-Furusho ◽  
K Bozada-Gutiérrez ◽  
A Sarmiento-Aguilar ◽  
A Fresan-Orellana ◽  
P Arguelles-Castro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Anxiety Disorders ◽  
Bowel Disease ◽  
Depression And Anxiety ◽  
Inflammatory Bowel

scholarly journals Depression, anxiety and stress among patients with inflammatory bowel disease during the COVID-19 pandemic: Australian national survey

2021 ◽  
Vol 8 (1) ◽  
pp. e000581
Author(s):  
Madiha Cheema ◽  
Nikola Mitrev ◽  
Leanne Hall ◽  
Maria Tiongson ◽  
Golo Ahlenstiel ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Severe Depression ◽  
Chronic Illnesses ◽  
Electronic Survey ◽  
Validated Questionnaire ◽  
Younger Age ◽  
Modifiable Factors ◽  
High Prevalence ◽  
Inflammatory Bowel

BackgroundThe global COVID-19 pandemic has impacted on the mental health of individuals, particularly those with chronic illnesses. We aimed to quantify stress, anxiety and depression among individuals with Inflammatory bowel disease (IBD) in Australia during the pandemic.MethodsAn electronic survey was made available to IBD patients Australia-wide from 17 June to 12 July 2020. Respondents with an underlying diagnosis of IBD and over 18 years of age were included. A validated questionnaire (Depression, Anxiety, Stress Score-21, DASS21) was used to assess depression, anxiety and stress. Data on potential predictors of depression, anxiety and stress were collected.Results352 participated in the survey across Australia. 60.5% of respondents fulfilled DASS criteria for at least moderate depression, anxiety or stress. 45% reported a pre-existing diagnosis of depression and/or anxiety. Over 2/3 of these respondents reported worsening of their pre-existing depression/anxiety due to the current pandemic. Of those without a pre-existing diagnosis of anxiety or depression, high rates of at least moderate to severe depression (34.9%), anxiety (32.0%) and stress (29.7%) were noted. Younger age (OR 0.96, 95% CI 0.94 to 0.98, p<0.001), lack of access to an IBD nurse (OR 1.81, 95% CI 1.03 to 3.19, p=0.04) and lack of education on reducing infection risk (OR 1.99, 95% CI 1.13 to 3.50, p=0.017) were associated with significant stress, anxiety and/or depression.ConclusionHigh prevalence of undiagnosed depression, anxiety and stress was identified among respondents. Improved access to IBD nurse support and greater attention to education are modifiable factors that may reduce depression, anxiety and/or stress among patients with IBD during the pandemic.

scholarly journals Controversies surrounding the comorbidity of depression and anxiety in inflammatory bowel disease patients

2007 ◽  
Vol 13 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Antonina A. Mikocka-Walus ◽  
Deborah A. Turnbull ◽  
Nicole T. Moulding ◽  
Ian G. Wilson ◽  
Jane M. Andrews ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Depression And Anxiety ◽  
Inflammatory Bowel

scholarly journals High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease

Gut ◽  
2007 ◽  
Vol 56 (5) ◽  
pp. 669-675 ◽  
Author(s):  
R. Kotlowski ◽  
C. N Bernstein ◽  
S. Sepehri ◽  
D. O Krause
Keyword(s):  
Escherichia Coli ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Phylogenetic Group ◽  
High Prevalence ◽  
Inflammatory Bowel

scholarly journals Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature

2020 ◽  
Vol 26 (7) ◽  
pp. 971-973 ◽  
Author(s):  
Melissa H Rosen ◽  
Jordan Axelrad ◽  
David Hudesman ◽  
David T Rubin ◽  
Shannon Chang
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
First Trimester ◽  
Review Of The Literature ◽  
Severe Ulcerative Colitis ◽  
Immune Mediated ◽  
First Trimester Of Pregnancy ◽  
Inflammatory Bowel ◽  
High Level

Abstract First detected in Wuhan, China, the novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped RNA beta-coronavirus responsible for an unprecedented, worldwide pandemic caused by COVID-19. Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 infection currently is based on expert opinion, given the novelty of the infection and the corresponding lack of high-level evidence in patients with immune-mediated conditions. There are limited data regarding IBD patients with COVID-19 and no data regarding early pregnancy in the era of COVID-19. This article describes a patient with acute severe ulcerative colitis (UC) during her first trimester of pregnancy who also has COVID-19. The case presentation is followed by a review of the literature to date on COVID-19 in regard to inflammatory bowel disease and pregnancy, respectively.

scholarly journals Combining Biologics in Inflammatory Bowel Disease and Other Immune Mediated Inflammatory Disorders

2018 ◽  
Vol 16 (9) ◽  
pp. 1374-1384 ◽  
Author(s):  
Robert P. Hirten ◽  
Marietta Iacucci ◽  
Shailja Shah ◽  
Subrata Ghosh ◽  
Jean-Frederic Colombel
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Inflammatory Disorders ◽  
Immune Mediated ◽  
Inflammatory Bowel

scholarly journals Su1143 Inflammatory Bowel Disease Patients Have a High Prevalence of Anal Human Papillomavirus and Anal Dysplasia

2013 ◽  
Vol 144 (5) ◽  
pp. S-410 ◽  
Author(s):  
Ross Cranston ◽  
Jonathan Baker ◽  
Carly Mowrey ◽  
Laura Janocko ◽  
Shaun Burneisen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Human Papillomavirus ◽  
Bowel Disease ◽  
Anal Dysplasia ◽  
High Prevalence ◽  
Inflammatory Bowel
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