scholarly journals AZFa protein DDX3Y is differentially expressed in human male germ cells during development and in testicular tumours: new evidence for phenotypic plasticity of germ cells

2012 ◽  
Vol 27 (6) ◽  
pp. 1547-1555 ◽  
Author(s):  
B. Gueler ◽  
S. B. Sonne ◽  
J. Zimmer ◽  
B. Hilscher ◽  
W. Hilscher ◽  
...  
Keyword(s):  
Phenotypic Plasticity ◽  
Germ Cells ◽  
Differentially Expressed ◽  
Male Germ Cells ◽  
Testicular Tumours ◽  
Human Male ◽  
New Evidence

scholarly journals O-062. In-vitro maturation of human male germ cells: a new treatment for maturation arrest at the primary spermatocyte stage

1999 ◽  
Vol 14 (Suppl_3) ◽  
pp. 33-34
Author(s):  
J. Tesarik ◽  
C. Mendoza ◽  
M. Bahceci ◽  
C. Özcan ◽  
E. Greco ◽  
...  
Keyword(s):  
Germ Cells ◽  
In Vitro Maturation ◽  
Primary Spermatocyte ◽  
Male Germ Cells ◽  
Maturation Arrest ◽  
Human Male ◽  
New Treatment

DECREASED AMOUNTS OF DESOXYRIBOSE NUCLEIC ACID (DNA) IN MALE GERM CELLS AS A POSSIBLE CAUSE OF HUMAN MALE INFERTILITY

1956 ◽  
Vol 6 (2) ◽  
pp. 272-278
Author(s):  
Cecilie Leuchtenberger ◽  
D.R. Weir ◽  
F. Schrader ◽  
R. Leuchtenberger
Keyword(s):  
Nucleic Acid ◽  
Male Infertility ◽  
Germ Cells ◽  
Male Germ Cells ◽  
Human Male ◽  
Possible Cause

scholarly journals Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells

2019 ◽  
Vol 21 (1) ◽  
pp. 25 ◽  
Author(s):  
Marco Barchi ◽  
Elisa Innocenzi ◽  
Teresa Giannattasio ◽  
Susanna Dolci ◽  
Pellegrino Rossi ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cells ◽  
Cannabinoid Receptors ◽  
Endocannabinoid System ◽  
Male Reproduction ◽  
Metabolizing Enzymes ◽  
Male Germ Cells ◽  
Testicular Tumours ◽  
Germ Cell Differentiation ◽  
Degradative Enzymes

Endocannabinoids are natural lipid molecules whose levels are regulated by specific biosynthetic and degradative enzymes. They bind to and activate two main cannabinoid receptors type 1 (CB1) and type 2 (CB2), and together with their metabolizing enzymes form the “endocannabinoid system” (ECS). In the last years, the relevance of endocannabinoids (eCBs) as critical modulators in various aspects of male reproduction has been pointed out. Mammalian male germ cells, from mitotic to haploid stage, have a complete ECS which is modulated during spermatogenesis. Compelling evidence indicate that in the testis an appropriate “eCBs tone”, associated to a balanced CB receptors signaling, is critical for spermatogenesis and for the formation of mature and fertilizing spermatozoa. Any alteration of this system negatively affects male reproduction, from germ cell differentiation to sperm functions, and might have also an impact on testicular tumours. Indeed, most of testicular tumours develop during early germ-cell development in which a maturation arrest is thought to be the first key event leading to malignant transformation. Considering the ever-growing number and complexity of the data on ECS, this review focuses on the role of cannabinoid receptors CB1 and CB2 signaling in male germ cells development from gonocyte up to mature spermatozoa and in the induction of epigenetic alterations in these cells which might be transmitted to the progeny. Furthermore, we present new evidence on their relevance in testicular cancer.

Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility?

2003 ◽  
Vol 289 (2) ◽  
pp. 295-306 ◽  
Author(s):  
Annie Munier ◽  
Catherine Serres ◽  
Marie-Louise Kann ◽  
Mathieu Boissan ◽  
Corinne Lesaffre ◽  
...  
Keyword(s):  
Sperm Motility ◽  
Germ Cells ◽  
Male Germ Cells ◽  
Human Male

Specific Expression of VCY2 in Human Male Germ Cells and Its Involvement in the Pathogenesis of Male Infertility

2003 ◽  
Vol 69 (3) ◽  
pp. 746-751 ◽  
Author(s):  
J.Y.M. Tse ◽  
E.Y.M. Wong ◽  
A.N.Y. Cheung ◽  
W.S. O ◽  
P.C. Tam ◽  
...  
Keyword(s):  
Male Infertility ◽  
Germ Cells ◽  
Specific Expression ◽  
Male Germ Cells ◽  
Human Male

scholarly journals Tat1, a Novel Sulfate Transporter Specifically Expressed in Human Male Germ Cells and Potentially Linked to RhoGTPase Signaling

2001 ◽  
Vol 276 (23) ◽  
pp. 20309-20315 ◽  
Author(s):  
Aminata Touré ◽  
Laurence Morin ◽  
Charles Pineau ◽  
Frédéric Becq ◽  
Olivier Dorseuil ◽  
...  
Keyword(s):  
Germ Cells ◽  
Sulfate Transporter ◽  
Male Germ Cells ◽  
Human Male
Sign in / Sign up

Export Citation Format

Share Document