scholarly journals Human semen quality and sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides

2008 ◽  
Vol 23 (8) ◽  
pp. 1932-1940 ◽  
Author(s):  
J. D. Meeker ◽  
D. B. Barr ◽  
R. Hauser
Keyword(s):  
Dna Damage ◽  
Semen Quality ◽  
Urinary Metabolites ◽  
Human Semen ◽  
Pyrethroid Insecticides ◽  
Sperm Dna Damage ◽  
Sperm Dna

Human Semen Quality, Sperm DNA Damage, and the Level of Reproductive Hormones in Relation to Urinary Concentrations of Parabens

2017 ◽  
Vol 59 (11) ◽  
pp. 1034-1040 ◽  
Author(s):  
Joanna Jurewicz ◽  
Michał Radwan ◽  
Bartosz Wielgomas ◽  
Emila Dziewirska ◽  
Anetta Karwacka ◽  
...  
Keyword(s):  
Dna Damage ◽  
Semen Quality ◽  
Reproductive Hormones ◽  
Human Semen ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals Human semen quality and sperm DNA damage assessed bycomet assay in clinical groups

2015 ◽  
Vol 45 ◽  
pp. 729-737 ◽  
Author(s):  
Muhammad Haris RAMZAN ◽  
Muhammad RAMZAN ◽  
Muhammad Mumtaz KHAN ◽  
Faiqah RAMZAN ◽  
Fazal WAHAB ◽  
...  
Keyword(s):  
Dna Damage ◽  
Semen Quality ◽  
Human Semen ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals Urinary Concentrations of Parabens and Serum Hormone Levels, Semen Quality Parameters, and Sperm DNA Damage

2011 ◽  
Vol 119 (2) ◽  
pp. 252-257 ◽  
Author(s):  
John D. Meeker ◽  
Tiffany Yang ◽  
Xiaoyun Ye ◽  
Antonia M. Calafat ◽  
Russ Hauser
Keyword(s):  
Dna Damage ◽  
Semen Quality ◽  
Quality Parameters ◽  
Hormone Levels ◽  
Sperm Dna Damage ◽  
Sperm Dna ◽  
Serum Hormone

scholarly journals Does the gp130 adenine (A)/thymine (T) (rs1900173) gene polymorphism affect semen quality or sperm DNA damage?

2019 ◽  
Vol 112 (3) ◽  
pp. e374
Author(s):  
Joao Batista A. Oliveira ◽  
Claudia G. Petersen ◽  
Ana Lucia Mauri ◽  
Adriana Renzi ◽  
Laura D. Vagnini ◽  
...  
Keyword(s):  
Dna Damage ◽  
Gene Polymorphism ◽  
Semen Quality ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals The aging male: Relationship between male age, sperm quality and sperm DNA damage in an unselected population of 3124 men attending the fertility centre for the first time

2019 ◽  
Vol 90 (4) ◽  
pp. 254-259 ◽  
Author(s):  
Alessandro Colasante ◽  
Maria Giulia Minasi ◽  
Filomena Scarselli ◽  
Valentina Casciani ◽  
Vincenzo Zazzaro ◽  
...  
Keyword(s):  
Dna Damage ◽  
Sperm Morphology ◽  
Semen Quality ◽  
Sperm Quality ◽  
World Health ◽  
Semen Parameters ◽  
Sperm Dna Fragmentation ◽  
Sperm Dna Damage ◽  
Male Age ◽  
Sperm Dna

Objective: the aim of our study was to put forward insights to treat any possible correlation among sperm quality, sperm DNA damage and male age as they may have fertility implications for men who choose to delay fatherhood. Materials and methods: Our study is a non-interventional retrospective analysis of 3124 semen samples from patients that were investigated for the conventional semen parameters. Tunel test assay was set up for the evaluation of the sperm DNA fragmentation index (DFI). We applied the Kappa index to compare both the 1999 and the 2010 World Health Organization (WHO) reference criteria to evaluate the competence of such semen parameters categorization during the standard routine of our laboratory. Results: With regards to our findings, it is possible to underline a significant relationship between aging and semen volume (p = 0.001), motility (p = 0.009), semen viscosity (p < 0.003) and sperm DNA damage (p < 0.009). We found a trend when focusing on the semen concentration (p = 0.05). The analysis of sperm morphology did not show any influence with advancing age (p = 0.606). When comparing both the 1999 and the 2010 WHO scales we found no accordance in the appraisal of sperm morphology but a very good one in the evaluation of the other parameters. Conclusions: Conventional semen analysis represents the opportunity to draw up a proxy insight on the male fertility status even if semen quality can only indirectly assess the probability of pregnancy. Several studies have verified a decay in the male reproductive system, sperm quality and fertility with advancing age although the reported results are not yet conclusive. Our results substantially agree with those findings outlined in the literature. Moreover we find that the discrepancy between the two WHO reference scales would eventually lead to an improper diagnosis of infertility.

scholarly journals Human Semen Quality, Sperm DNA Damage, and the Level of Urinary Concentrations of 1N and TCPY, the Biomarkers of Nonpersistent Insecticides

2018 ◽  
Vol 13 (1) ◽  
pp. 155798831881659 ◽  
Author(s):  
Emila Dziewirska ◽  
Michał Radwan ◽  
Bartosz Wielgomas ◽  
Anna Klimowska ◽  
Paweł Radwan ◽  
...  
Keyword(s):  
Dna Damage ◽  
Environmental Exposure ◽  
Semen Quality ◽  
Semen Analysis ◽  
Positive Association ◽  
Quality Parameters ◽  
Normal Morphology ◽  
Sperm Dna Damage ◽  
Fragmentation Index ◽  
Sperm Dna

The aim of the study was to evaluate the association between environmental exposure to nonpersistent insecticides and semen quality (concentration, motility, morphology, computer-aided semen analysis [CASA] parameters, and sperm DNA damage). Urine samples ( n = 315) collected from men who attended the infertility clinic with normal semen concentration of 15 to 300 mln/ml and age under 45 years were analyzed for two metabolites (1-naphthol [1N] and 3,5,6-trichloro-2-pyridinol [TCPY]) of nonpersistent insecticides. Participants provided semen, blood, and saliva samples; additionally, men filled a detailed questionnaire. The results identified that urinary TCPY concentration was significantly associated with a decrease in motility; also there was a positive association between TCPY and DNA fragmentation index (DFI). 1N concentration was negatively associated with a percentage of sperm with normal morphology and positively with one of the CASA parameters (curvilinear velocity [VCL]). The results suggest that environmental exposure to nonpersistent insecticides may have an impact on semen quality parameters and sperm DNA damage.

scholarly journals Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic☆☆☆

2010 ◽  
Vol 30 (4) ◽  
pp. 532-539 ◽  
Author(s):  
John D. Meeker ◽  
Shelley Ehrlich ◽  
Thomas L. Toth ◽  
Diane L. Wright ◽  
Antonia M. Calafat ◽  
...  
Keyword(s):  
Dna Damage ◽  
Bisphenol A ◽  
Semen Quality ◽  
Sperm Dna Damage ◽  
Sperm Dna
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