Effect of cold storage and cryopreservation of immature non-human primate testicular tissue on spermatogonial stem cell potential in xenografts

2006 ◽  
Vol 22 (4) ◽  
pp. 1060-1067 ◽  
Author(s):  
Kirsi Jahnukainen ◽  
Jens Ehmcke ◽  
Scott D. Hergenrother ◽  
Stefan Schlatt
Keyword(s):  
Stem Cell ◽  
Cold Storage ◽  
Testicular Tissue ◽  
Spermatogonial Stem Cell ◽  
Cell Potential ◽  
Stem Cell Potential ◽  
Human Primate

Spermatogonial stem cell potential of CXCR4-positive cells from prepubertal bull testes

2018 ◽  
Vol 196 ◽  
pp. 219-229 ◽  
Author(s):  
Marcelo D. Goissis ◽  
Mariana I. Giassetti ◽  
Robinson A. Worst ◽  
Camilla M. Mendes ◽  
Pedro V. Moreira ◽  
...  
Keyword(s):  
Stem Cell ◽  
Spermatogonial Stem Cell ◽  
Cell Potential ◽  
Stem Cell Potential

scholarly journals Canine Mesenchymal Stem Cell Potential and the Importance of Dog Breed: Implication for Cell-Based Therapies

2015 ◽  
Vol 24 (10) ◽  
pp. 1969-1980 ◽  
Author(s):  
Alessandro Bertolo ◽  
Frank Steffen ◽  
Cherry Malonzo-Marty ◽  
Jivko Stoyanov
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Potential ◽  
Dog Breed ◽  
Stem Cell Potential

P-glycoprotein expression and stem cell potential

2000 ◽  
Vol 28 (7) ◽  
pp. 68-69
Author(s):  
Fiona Spratt ◽  
Suzanne Micallef ◽  
Brenda Williams ◽  
Michele Cook ◽  
Ivan Bertoncello
Keyword(s):  
Stem Cell ◽  
Cell Potential ◽  
P Glycoprotein ◽  
Stem Cell Potential

scholarly journals iPSC-Derived MSCs Versus Originating Jaw Periosteal Cells: Comparison of Resulting Phenotype and Stem Cell Potential

2020 ◽  
Vol 21 (2) ◽  
pp. 587 ◽  
Author(s):  
Felix Umrath ◽  
Marbod Weber ◽  
Siegmar Reinert ◽  
Hans-Peter Wendel ◽  
Meltem Avci-Adali ◽  
...  
Keyword(s):  
Stem Cell ◽  
Progenitor Cells ◽  
Induced Pluripotent Stem Cell ◽  
Mitochondrial Activity ◽  
Cell Potential ◽  
Differentiation Potential ◽  
Periosteal Cells ◽  
Induced Pluripotent ◽  
Stem Cell Potential ◽  
Promising Source

Induced pluripotent stem cell-derived mesenchymal stem cell-like cells (iMSCs) are considered to be a promising source of progenitor cells for approaches in the field of bone regeneration. In a previous study, we described the generation of footprint-free induced pluripotent stem cells (iPSCs) from human jaw periosteal cells (JPCs) by transfection of a self-replicating RNA (srRNA) and subsequent differentiation into functional osteogenic progenitor cells. In order to facilitate the prospective transfer into clinical practice, xeno-free reprogramming and differentiation methods were established. In this study, we compared the properties and stem cell potential of the iMSCs produced from JPC-derived iPSCs with the parental primary JPCs they were generated from. Our results demonstrated, on the one hand, a comparable differentiation potential of iMSCs and JPCs. Additionally, iMSCs showed significantly longer telomere lengths compared to JPCs indicating rejuvenation of the cells during reprogramming. On the other hand, proliferation, mitochondrial activity, and senescence-associated beta-galactosidase (SA-β-gal) activity indicated early senescence of iMSCs. These data demonstrate the requirement of further optimization strategies to improve mesenchymal development of JPC-derived iPSCs in order to take advantage of the best features of reprogrammed and rejuvenated cells.

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