scholarly journals Effect of first-trimester serum from pregnant women with high-resistance uterine artery Doppler resistance on extravillous trophoblast invasion

2006 ◽  
Vol 21 (5) ◽  
pp. 1295-1298 ◽  
Author(s):  
R. Ganapathy ◽  
L.J. Ayling ◽  
G.S.J. Whitley ◽  
J.E. Cartwright ◽  
B. Thilaganathan
Keyword(s):  
Pregnant Women ◽  
High Resistance ◽  
Uterine Artery ◽  
First Trimester ◽  
Extravillous Trophoblast ◽  
Trophoblast Invasion ◽  
Uterine Artery Doppler

scholarly journals Uterine Artery Doppler Ultrasonography for First Trimester Prediction of Preeclampsia in Individuals at Risk from Low-Resource Settings

Medicina ◽  
2020 ◽  
Vol 56 (9) ◽  
pp. 428
Author(s):  
Mihaela Oancea ◽  
Mihaela Grigore ◽  
Razvan Ciortea ◽  
Doru Diculescu ◽  
Diana Bodean ◽  
...  
Keyword(s):  
At Risk ◽  
Pregnant Women ◽  
Uterine Artery ◽  
Doppler Ultrasonography ◽  
First Trimester ◽  
Prospective Longitudinal Study ◽  
Uterine Artery Doppler ◽  
Doppler Examination ◽  
Non Invasive ◽  
Prospective Longitudinal

Background and objectives: The objective of this study was to evaluate the potential of first trimester uterine artery Doppler ultrasonography for the early prediction of preeclampsia (PE), in at-risk pregnant women. Materials and Methods: This was a prospective longitudinal study, including 120 Caucasian pregnant women with risk factors for PE. The potential of pulsatility indexes (PI) and notch was assessed as a tool for preeclampsia screening. Results: Doppler examination of the uterine artery performed early at 11–14 WA allows the detection of pregnancies that will develop PE with a sensitivity of 61.5% and a specificity of 63.8% based on PI analysis. Predictive power increases slightly by adding bilateral notch (sensitivity = 65.4%; specificity = 66%). Conclusions: Uterine artery Doppler examination is an effective non-invasive screening test for the development of PE in pregnancies at risk, particularly appropriate in health systems with limited means of evaluating other biomarkers.

P08.01: Relationship of uterine artery Doppler and trophoblast invasion in the first trimester of pregnancy

2004 ◽  
Vol 24 (3) ◽  
pp. 313-313 ◽  
Author(s):  
R. Ganapathy ◽  
B. Thilaganathan ◽  
J. Cartwright ◽  
G. Whitley ◽  
L. J. Ayling ◽  
...  
Keyword(s):  
Uterine Artery ◽  
First Trimester ◽  
Trophoblast Invasion ◽  
Uterine Artery Doppler ◽  
First Trimester Of Pregnancy ◽  
Relationship Of

scholarly journals Serum hypoxia-inducible factor-1α and uterine artery Doppler ultrasound during the first trimester for prediction of preeclampsia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wasinee Tianthong ◽  
Vorapong Phupong
Keyword(s):  
Pregnant Women ◽  
Doppler Ultrasound ◽  
Predictive Value ◽  
Uterine Artery ◽  
Hypoxia Inducible Factor ◽  
First Trimester ◽  
Singleton Pregnancy ◽  
Uterine Artery Doppler ◽  
Hypoxia Inducible Factor 1Α ◽  
Sensitivity Specificity

AbstractThe objective of this study was to determine the predictive value of serum hypoxia-inducible factor-1α (HIF-1α) combined with uterine artery Doppler in singleton pregnancy during 11–13+6 weeks of gestation for preeclampsia. This prospective observational study was conducted in singleton pregnant women at 11–13+6 weeks of gestation who visited the King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University for antenatal care between February 2019 and May 2020. Serum HIF-1α levels and uterine artery Doppler ultrasound were performed. Pregnancy outcomes were recorded. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of these tests at the optimal cut-off values were determined to predict preeclampsia. A total of 385 participants were analyzed. Of these, 31 cases had preeclampsia (8.1%), and 6 cases of them had early-onset preeclampsia (1.6%). Preeclamptic women had significantly higher serum HIF-1α levels than normal pregnant women (median 1315.2 pg/ml vs. 699.5 pg/ml, p < 0.001). There was no difference in the mean pulsatility (PI) of the uterine artery. Serum HIF-1α levels were higher than 1.45 multiple of median for the gestational age as a cut-off value for predicting preeclampsia; the sensitivity, specificity, PPV, and NPV were 66.7%, 71.5%, 17.2%, and 96.2%, respectively. When a combination of abnormal serum HIF-1α levels and abnormal uterine artery Doppler PI (above the 95th percentile) were used as a predictive value to predict preeclampsia, the sensitivity, specificity, PPV, and NPV were 74.2%, 67.2%, 16.6%, and 96.8%, respectively. This study showed that the serum HIF-1α levels with or without uterine artery Doppler at 11–13+6 weeks of gestation were effective in predicting preeclampsia.

scholarly journals EP08.13: Performance of first trimester uterine artery Doppler in the prediction of pre-eclampsia

2015 ◽  
Vol 46 ◽  
pp. 212-212
Author(s):  
G.R. Lobo ◽  
P.M. Nowak ◽  
L. Nardozza ◽  
D.S. Pares
Keyword(s):  
Uterine Artery ◽  
First Trimester ◽  
Uterine Artery Doppler

First trimester uterine artery Doppler and subsequent intrauterine growth restriction and preterm birth

2004 ◽  
Vol 191 (6) ◽  
pp. S22
Author(s):  
Lorraine Dugoff ◽  
John Hobbins ◽  
Vincent Faber ◽  
Fergal Malone ◽  
Michael Belfort ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
First Trimester ◽  
Growth Restriction ◽  
Uterine Artery Doppler ◽  
Intrauterine Growth
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